POLR2M and RPL7A

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLR2M	RPL7A
Gene Name		polymerase (RNA) II (DNA directed) polypeptide M	ribosomal protein L7a
Image
Gene Ontology Annotations	Cellular Component	Nuclear Envelope DNA-directed RNA Polymerase II, Holoenzyme Neuronal Cell Body	Nucleus Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome Extracellular Vesicular Exosome
	Molecular Function	DNA-directed RNA Polymerase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	RNA Biosynthetic Process Maintenance Of ER Location	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosome Biogenesis Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: AHSP ANKHD1 APOD CEBPG DGKZ HIGD1B KIAA1377 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410	7 interactors: CCDC47 CTBP2 MKNK2 POLR2M SGOL1 SOCS3 STAU1
Entrez ID		81488	6130
HPRD ID		07575	01712
Ensembl ID		ENSG00000255529	ENSG00000148303
Uniprot IDs		P0CAP1 P0CAP2 Q6EEV4	P62424
PDB IDs		2KXS	3J3B
Enriched GO Terms of Interacting Partners?		Viral Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of T Cell Migration Negative Regulation Of Lipoprotein Lipid Oxidation Transmission Of Virus Development Involved In Symbiotic Interaction Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Subthalamus Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Lipoprotein Lipid Oxidation Mitotic DNA Damage Checkpoint Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Interaction With Host Regulation Of Mitotic Cell Cycle Negative Regulation Of Lymphocyte Migration Regulation Of Intracellular Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Progesterone Receptor Signaling Pathway Developmental Process	Maintenance Of ER Location Maintenance Of Location In Cell Positive Regulation By Virus Of Viral Protein Levels In Host Cell Endoplasmic Reticulum Localization Spongiotrophoblast Differentiation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Centriole-centriole Cohesion Positive Regulation Of Chromatin Binding
Tagcloud ?			arranged birds caenorhabditis clustered clustering dilysine drosophila elegans evolutionary genomes homologs integral invertebrate juxtaposition lineages mammals melanogaster polymorphic requirement seryl surf surfeit synthetase tata tight tightest transcribed trna vertebrate
Tagcloud (Difference) ?			arranged birds caenorhabditis clustered clustering dilysine drosophila elegans evolutionary genomes homologs integral invertebrate juxtaposition lineages mammals melanogaster polymorphic requirement seryl surf surfeit synthetase tata tight tightest transcribed trna vertebrate
Tagcloud (Intersection) ?