DMD and CADPS2

Number of citations of the paper that reports this interaction (PMID 12659812)
11

Data Source:
HPRD (two hybrid)

		DMD	CADPS2
Gene Name		dystrophin	Ca++-dependent secretion activator 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Plasma Membrane Cell Surface Actin Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Cell Junction Filopodium Filopodium Membrane Sarcolemma Costamere Protein Complex Membrane Raft Postsynaptic Membrane	Cell Junction Cytoplasmic Vesicle Membrane Presynaptic Membrane Postsynaptic Membrane
	Molecular Function	Dystroglycan Binding Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Zinc Ion Binding Structural Constituent Of Muscle Myosin Binding Vinculin Binding Nitric-oxide Synthase Binding	Lipid Binding Metal Ion Binding
	Biological Process	Regulation Of Heart Rate Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Neuron Projection Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction Muscle Filament Sliding Extracellular Matrix Organization Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Protein Localization Peptide Biosynthetic Process Cellular Protein Complex Assembly Motile Cilium Assembly Positive Regulation Of Neuron Differentiation Cardiac Muscle Contraction Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Cell Action Potential Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity	Cellular Response To Starvation Protein Transport Synaptic Vesicle Priming Positive Regulation Of Exocytosis
Pathways		Striated Muscle Contraction Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS		Response to antidepressant treatment ( 22041458)	Brain structure ( 20171287)
Protein-Protein Interactions		27 interactors: ACTA1 ACTC1 APP CADPS CADPS2 CDC25A CTNNAL1 DAG1 DGKZ DISC1 DTNA DTNB FASLG HAUS1 KCNJ12 KRT19 KRT8 MAP3K5 PGM5 SGCZ SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 TRAF3IP1 UTRN	14 interactors: BDNF BZRAP1 DMD DRD2 MEGF10 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2U UBE2W
Entrez ID		1756	93664
HPRD ID		02303	12996
Ensembl ID		ENSG00000198947	ENSG00000081803
Uniprot IDs		A1L0U9 A7E212 P11532 Q16484 Q4G0X0	B7ZM57 Q86UW7
PDB IDs		1DXX 1EG3 1EG4 3UUN
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Muscle Cell Development Myofibril Assembly Actomyosin Structure Organization Organelle Assembly Cellular Component Assembly Muscle Structure Development Muscle Cell Differentiation Skeletal Muscle Thin Filament Assembly Striated Muscle Cell Development Skeletal Myofibril Assembly Synaptic Vesicle Priming Striated Muscle Cell Differentiation Organ Development Cytoskeleton Organization Organelle Organization Muscle Organ Development Positive Regulation Of Proteolysis Cell Development System Development Positive Regulation Of Peptidase Activity Cell Differentiation Involved In Embryonic Placenta Development Actin-myosin Filament Sliding Muscle Filament Sliding Movement Of Cell Or Subcellular Component Regulation Of Sodium Ion Transmembrane Transport Microtubule-based Process Actin-mediated Cell Contraction Programmed Necrotic Cell Death Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Necrotic Cell Death Multicellular Organismal Development Sarcomere Organization Neuromuscular Junction Development Synaptic Vesicle Exocytosis Anatomical Structure Development Actin Filament-based Movement Cell-cell Signaling Heart Contraction Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Calcium-dependent Cell-matrix Adhesion Regulation Of Sodium Ion Transport Anatomical Structure Morphogenesis Viral Process Apoptotic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Toll-like Receptor Signaling Pathway Response To Hypoxia Protein K63-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Histone Ubiquitination Activation Of Innate Immune Response Protein Monoubiquitination Positive Regulation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Acid Secretion TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Proteolysis Regulation Of Innate Immune Response Positive Regulation Of Ligase Activity Cellular Protein Modification Process Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Catabolic Process Cellular Response To Oxygen Levels Response To Auditory Stimulus Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Ubiquitination Glutamate Secretion Positive Regulation Of Protein Modification Process Immune Response-regulating Signaling Pathway Cellular Response To Stress Regulation Of Long-term Neuronal Synaptic Plasticity Cellular Protein Metabolic Process Mitotic Spindle Assembly Checkpoint
Tagcloud ?		2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2	alteration alterations arf frequently gain genomic hot ink4a instability mutants mutation mutations obvious p16 p53 piwil4 point prepared reason restraining resulting saos specificity spot suppresses suppressor transcriptional trim9 tumors
Tagcloud (Difference) ?		2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2	alteration alterations arf frequently gain genomic hot ink4a instability mutants mutation mutations obvious p16 p53 piwil4 point prepared reason restraining resulting saos specificity spot suppresses suppressor transcriptional trim9 tumors
Tagcloud (Intersection) ?