TXNDC17 and DYNLL1

Number of citations of the paper that reports this interaction (PMID 14607843)
14

Data Source:
HPRD (in vitro)

		TXNDC17	DYNLL1
Gene Name		thioredoxin domain containing 17	dynein, light chain, LC8-type 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Kinetochore Nucleus Cytoplasm Mitochondrion Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane COP9 Signalosome Membrane Extracellular Vesicular Exosome Primary Cilium Mitotic Spindle Ciliary Tip
	Molecular Function	Peroxidase Activity Protein Binding Electron Carrier Activity Protein-disulfide Reductase Activity	Motor Activity Protein Binding Protein C-terminus Binding Enzyme Binding Protein Domain Specific Binding Nitric-oxide Synthase Regulator Activity Protein Homodimerization Activity
	Biological Process	Tumor Necrosis Factor-mediated Signaling Pathway Oxidation-reduction Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transport Apoptotic Process Organelle Organization Microtubule-based Process Female Gamete Generation Anatomical Structure Morphogenesis Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Substantia Nigra Development Actin Cytoskeleton Organization Negative Regulation Of Phosphorylation Regulation Of Catalytic Activity Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways			Organelle biogenesis and maintenance Activation of BH3-only proteins Assembly of the primary cilium G2/M Transition Anchoring of the basal body to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic Intraflagellar transport Loss of proteins required for interphase microtubule organizationÂ from the centrosome Activation of BIM and translocation to mitochondria Loss of Nlp from mitotic centrosomes MHC class II antigen presentation Programmed Cell Death Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes Adaptive Immune System Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AVP DYNLL1 EXOSC8 INS OXT RUFY1 TINF2 TXNRD1	77 interactors: ACTB ACTC1 ACTG1 ALDOA AMBRA1 AMOTL2 B3GALT4 BCAS1 BCL2L11 BMF C14orf1 CA2 CACNB1 CCDC36 CLIP2 CS DAZ1 DLG4 DLGAP1 DNAJB9 DNM2 DNM3 DNMT1 DYNC1H1 DYNC1I1 EEF1A1 GAPDH GLUD1 GLUL GNB2L1 GPHN GRIN3A HIP1R HSPA8 INPP1 IQUB KANK2 LDHA MAP1B MARK3 MAST2 ME2 MTA1 MTR MYO10 MYO5A NDUFA4L2 NFKBIA NOS1 NRF1 NTRK1 NTRK2 NTRK3 PAK1 PAN2 PARD3 PAX6 PFKM PFKP PKIA PKIB PKIG POLH RAB4A RGS2 SHROOM3 TERT THAP8 TNFRSF14 TP53BP1 TUBA3C TUBB TXNDC17 VIM ZHX1 ZMYND11 ZNF354A
Entrez ID		84817	8655
HPRD ID		11656	03334
Ensembl ID		ENSG00000129235	ENSG00000088986
Uniprot IDs		Q9BRA2	P63167 Q6FGH9
PDB IDs		1WOU	1CMI 3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?		Maternal Aggressive Behavior Hyperosmotic Salinity Response Aggressive Behavior Regulation Of Cellular Component Organization Regulation Of Female Receptivity Maternal Behavior Female Mating Behavior Grooming Behavior Regulation Of Renal Sodium Excretion Copulation Hyperosmotic Response Regulation Of Excretion Homeostatic Process Mating Behavior Positive Regulation Of Transport Response To Salt Stress Positive Regulation Of Blood Pressure Social Behavior Positive Regulation Of Secretion Mating Regulation Of Organelle Organization Regulation Of Neurological System Process Positive Regulation Of Lipid Biosynthetic Process Regulation Of Cellular Localization Positive Regulation Of Organelle Organization Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Hindgut Contraction Regulation Of Fatty Acid Metabolic Process Response To Osmotic Stress Regulation Of Mitochondrion Organization Renal System Process Regulation Of Protein ADP-ribosylation Negative Regulation Of Glycogen Catabolic Process Regulation Of Hindgut Contraction Ion Homeostasis Positive Regulation Of Cell Growth Regulation Of DNA Replication Regulation Of Lipid Biosynthetic Process Regulation Of Anion Transport Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Negative Regulation Of NAD(P)H Oxidase Activity Regulation Of Secretion Positive Regulation Of DNA Metabolic Process Response To Alkaloid Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Cellular Homeostasis Regulation Of Ion Homeostasis Positive Regulation Of Cellular PH Reduction Positive Regulation Of Norepinephrine Secretion	Nervous System Development Movement Of Cell Or Subcellular Component Cell Differentiation Developmental Process Regulation Of Cellular Component Organization Response To Organic Substance Regulation Of Cellular Localization Neuron Projection Morphogenesis Axonogenesis Cellular Response To Stimulus Synapse Organization Neuron Projection Development Neuron Development Regulation Of Cellular Protein Metabolic Process Response To Stimulus Neuron Differentiation Regulation Of Protein Metabolic Process Axon Development Cell Projection Morphogenesis Response To External Stimulus Anatomical Structure Morphogenesis Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Cell Part Morphogenesis Cellular Process Negative Regulation Of CAMP-dependent Protein Kinase Activity Positive Regulation Of Protein Homooligomerization Cell Morphogenesis Axon Guidance Negative Regulation Of Phosphorylation Regulation Of Cellular Process Glycolytic Process Locomotion Cell Development Negative Regulation Of Protein Phosphorylation Cytoskeleton Organization Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Membrane Organization Regulation Of CAMP-dependent Protein Kinase Activity Cell Morphogenesis Involved In Differentiation Anatomical Structure Development Generation Of Neurons System Development Response To Stress Regulation Of Protein Phosphorylation Multicellular Organismal Development Neuromuscular Junction Development Pyruvate Metabolic Process Actin Filament-based Process
Tagcloud ?			1inq53a 250viqd 52gqvd adapter attempt capsid defective dynein hiv immunodeficiency integrase interaction kd ma motifs mutational p150glued particulate predicts proper q252a replication requirement reverse steps tctex transcriptase uncoating
Tagcloud (Difference) ?			1inq53a 250viqd 52gqvd adapter attempt capsid defective dynein hiv immunodeficiency integrase interaction kd ma motifs mutational p150glued particulate predicts proper q252a replication requirement reverse steps tctex transcriptase uncoating
Tagcloud (Intersection) ?