TXNDC17 and TINF2

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		TXNDC17	TINF2
Gene Name		thioredoxin domain containing 17	TERF1 (TRF1)-interacting nuclear factor 2
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Perinucleolar Chromocenter Nuclear Matrix
	Molecular Function	Peroxidase Activity Protein Binding Electron Carrier Activity Protein-disulfide Reductase Activity	DNA Binding Protein Binding Telomeric DNA Binding
	Biological Process	Tumor Necrosis Factor-mediated Signaling Pathway Oxidation-reduction Process	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Protein ADP-ribosylation Telomere Assembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome Negative Regulation Of Epithelial Cell Proliferation Protein Localization To Chromosome, Telomeric Region
Pathways			Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AVP DYNLL1 EXOSC8 INS OXT RUFY1 TINF2 TXNRD1	88 interactors: ACD ACOT7 ACTB ADA AFAP1L2 AIPL1 AK1 ANKMY2 ANXA4 ANXA5 APOBEC3F APPL2 ARHGDIA ARID3B BAG3 BIN2 CALD1 CCDC43 CCDC9 CKB CLK3 CPNE3 CRYGS CTTN DBN1 DCX DHFRL1 DPP3 EEF1D EIF4B ENO2 FAM131B FERMT3 FKBP6 GAPDH GNMT HNMT HOXA3 HSP90AB1 IPO5 KCTD17 LASP1 LDHA LGALSL LTA4H MAP2K3 NCDN NOL3 NUDC NUDCD2 OR2H1 PAGE2 PAK1IP1 PEX5 PFKP PGM1 PGM2 PHPT1 PKM POT1 PPP1R2 PPP6R3 PRKCB REM2 RGS14 RPSA SARS SCRN2 SIAH2 STUB1 SULT1C2 TAGLN TBL1X TERF1 TERF2 TOMM34 TPP1 TRIM15 TRIM16 TRIP10 TUBB TUBB4B TXNDC17 UCHL1 VIPR1 YWHAG ZFP36L1 ZNF790
Entrez ID		84817	26277
HPRD ID		11656	16056
Ensembl ID		ENSG00000129235	ENSG00000092330
Uniprot IDs		Q9BRA2	B4DFJ1 Q9BSI4
PDB IDs		1WOU	3BQO 3BU8
Enriched GO Terms of Interacting Partners?		Maternal Aggressive Behavior Hyperosmotic Salinity Response Aggressive Behavior Regulation Of Cellular Component Organization Regulation Of Female Receptivity Maternal Behavior Female Mating Behavior Grooming Behavior Regulation Of Renal Sodium Excretion Copulation Hyperosmotic Response Regulation Of Excretion Homeostatic Process Mating Behavior Positive Regulation Of Transport Response To Salt Stress Positive Regulation Of Blood Pressure Social Behavior Positive Regulation Of Secretion Mating Regulation Of Organelle Organization Regulation Of Neurological System Process Positive Regulation Of Lipid Biosynthetic Process Regulation Of Cellular Localization Positive Regulation Of Organelle Organization Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Hindgut Contraction Regulation Of Fatty Acid Metabolic Process Response To Osmotic Stress Regulation Of Mitochondrion Organization Renal System Process Regulation Of Protein ADP-ribosylation Negative Regulation Of Glycogen Catabolic Process Regulation Of Hindgut Contraction Ion Homeostasis Positive Regulation Of Cell Growth Regulation Of DNA Replication Regulation Of Lipid Biosynthetic Process Regulation Of Anion Transport Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Negative Regulation Of NAD(P)H Oxidase Activity Regulation Of Secretion Positive Regulation Of DNA Metabolic Process Response To Alkaloid Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Cellular Homeostasis Regulation Of Ion Homeostasis Positive Regulation Of Cellular PH Reduction Positive Regulation Of Norepinephrine Secretion	Negative Regulation Of Telomere Maintenance Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Glycolytic Process Protection From Non-homologous End Joining At Telomere Carbohydrate Catabolic Process Negative Regulation Of DNA Replication Telomere Assembly Catabolic Process Negative Regulation Of DNA Metabolic Process Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Catalytic Activity Positive Regulation Of Telomerase Activity Pyruvate Metabolic Process Telomere Maintenance Telomere Maintenance Via Telomerase Pathogenesis Generation Of Precursor Metabolites And Energy Glucose Metabolic Process Positive Regulation Of Single-stranded Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of Chromosome Organization Small Molecule Metabolic Process Organic Acid Metabolic Process Regulation Of DNA Biosynthetic Process Regulation Of Catalytic Activity Carboxylic Acid Metabolic Process Age-dependent Telomere Shortening Telomeric Loop Formation Nervous System Development Regulation Of Signaling Positive Regulation Of DNA Biosynthetic Process Glycogen Metabolic Process RNA-dependent DNA Replication Nucleoside Metabolic Process Telomere Maintenance Via Telomere Shortening Regulation Of Signal Transduction Hexose Metabolic Process Cellular Process Regulation Of DNA Replication Monocarboxylic Acid Metabolic Process Cellular Carbohydrate Metabolic Process Response To Stimulus Protein Localization To Chromosome Organelle Organization Telomere Maintenance Via Telomere Lengthening Polysaccharide Metabolic Process
Tagcloud ?			acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 terf2 terf2ip yates
Tagcloud (Difference) ?			acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 terf2 terf2ip yates
Tagcloud (Intersection) ?