RUVBL2 and STOM

Number of citations of the paper that reports this interaction (PMID 10524211)
6

Data Source:
BioGRID (pull down)

		RUVBL2	STOM
Gene Name		RuvB-like AAA ATPase 2	stomatin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Swr1 Complex Intracellular Nucleus Nucleoplasm Nuclear Euchromatin Cytoplasm Membrane Nuclear Matrix Ribonucleoprotein Complex Ino80 Complex NuA4 Histone Acetyltransferase Complex Extracellular Vesicular Exosome MLL1 Complex	Extracellular Space Cytoplasm Cytoskeleton Integral Component Of Plasma Membrane Membrane Vesicle Melanosome Membrane Raft Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding DNA Helicase Activity Damaged DNA Binding ATP-dependent DNA Helicase Activity Protein Binding ATP Binding ATPase Activity Chromatin DNA Binding Identical Protein Binding ATP-dependent 5'-3' DNA Helicase Activity Unfolded Protein Binding	Protein Homodimerization Activity
	Biological Process	DNA Repair DNA Recombination Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Protein Folding DNA Duplex Unwinding Cellular Response To UV Positive Regulation Of Histone Acetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Establishment Of Protein Localization To Chromatin Cellular Response To Estradiol Stimulus Transcriptional Activation By Promoter-enhancer Looping Negative Regulation Of Estrogen Receptor Binding	Protein Homooligomerization Regulation Of Acid-sensing Ion Channel Activity
Pathways		Chromatin modifying enzymes Telomere Maintenance Chromosome Maintenance Chromatin organization Extension of Telomeres Telomere Extension By Telomerase HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: APP APPL1 APPL2 ATF2 BCL3 CCDC103 CDKN2A CTNNB1 DPCD EHMT2 EXOSC10 FBL FDFT1 HDAC1 HDAC4 LIG4 LNX1 MDM2 NDRG1 NUFIP1 PIH1D1 RUVBL1 STOM TAF9 TBP TERT YWHAQ	9 interactors: ASIC1 ASIC2 ASIC3 DVL3 LANCL1 RPL13A RUVBL1 RUVBL2 SLC2A1
Entrez ID		10856	2040
HPRD ID		16070	00585
Ensembl ID		ENSG00000183207	ENSG00000148175
Uniprot IDs		B3KNL2 B3KQ59 Q9Y230	P27105
PDB IDs		2CQA 2XSZ 3UK6
Enriched GO Terms of Interacting Partners?		Chromatin Modification Positive Regulation Of Gene Expression Chromatin Organization Chromosome Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Histone Modification Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Cellular Component Assembly Peptidyl-lysine Modification Apoptotic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Cell Death Death Regulation Of Protein Sumoylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Apoptotic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Death Box C/D SnoRNP Assembly Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Biosynthetic Process Histone H3-K9 Modification Developmental Process Posttranscriptional Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Sexual Reproduction Ribonucleoprotein Complex Biogenesis Gene Expression Cellular Response To DNA Damage Stimulus Negative Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Fungiform Papilla Formation Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Programmed Cell Death Chromatin Remodeling	Sensory Perception Of Sour Taste Response To PH Sensory Perception Of Taste Cellular Response To Stimulus Histone H2A Acetylation Cellular Response To PH Response To Acidic PH Response To Abiotic Stimulus Sodium Ion Transmembrane Transport Response To Stimulus Detection Of Mechanical Stimulus Involved In Sensory Perception Sodium Ion Transport Detection Of Mechanical Stimulus Histone H4 Acetylation DNA Duplex Unwinding DNA Geometric Change Enterobactin Transport Negative Regulation Of Formation Of Translation Preinitiation Complex Regulation Of Systemic Arterial Blood Pressure By Aortic Arch Baroreceptor Feedback Sensory Perception Of Chemical Stimulus Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Siderophore Transport Negative Regulation Of Estrogen Receptor Binding Transcriptional Activation By Promoter-enhancer Looping Protein Acetylation Dehydroascorbic Acid Transport Monovalent Inorganic Cation Transport Non-canonical Wnt Signaling Pathway Via JNK Cascade Detection Of Abiotic Stimulus Sensory Perception Of Mechanical Stimulus Regulation Of Cellular Process Chromatin Remodeling Xenobiotic Transport Non-canonical Wnt Signaling Pathway Via MAPK Cascade Establishment Of Protein Localization To Chromatin Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Transmembrane Transport Sensory Perception Ion Transport Cellular Response To Acidic PH Negative Regulation Of Receptor Binding Response To Mechanical Stimulus Metal Ion Transport DNA Recombination Peptidyl-lysine Modification Cation Transmembrane Transport
Tagcloud ?		ac accessible architecture attenuates baz1b clarify cytoprotective foci gammah2ax h2ax h3k56 h3k9 hubs integrated ints3 irradiation isoform mark matrix mount prevents proteomic respond runx runx2 scaffolding subnuclear supported
Tagcloud (Difference) ?		ac accessible architecture attenuates baz1b clarify cytoprotective foci gammah2ax h2ax h3k56 h3k9 hubs integrated ints3 irradiation isoform mark matrix mount prevents proteomic respond runx runx2 scaffolding subnuclear supported
Tagcloud (Intersection) ?