GTPBP3 and GNE

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GTPBP3	GNE
Gene Name		GTP binding protein 3 (mitochondrial)	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion	Cytoplasm Cytosol
	Molecular Function	GTPase Activity GTP Binding	Hydrolase Activity, Hydrolyzing O-glycosyl Compounds ATP Binding UDP-N-acetylglucosamine 2-epimerase Activity N-acylmannosamine Kinase Activity Metal Ion Binding
	Biological Process	TRNA Modification	N-acetylglucosamine Biosynthetic Process UDP-N-acetylglucosamine Metabolic Process N-acetylneuraminate Metabolic Process Dolichol-linked Oligosaccharide Biosynthetic Process Cell Adhesion Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process Carbohydrate Phosphorylation
Pathways			Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Post-translational protein modification Defective ALG3 causes ALG3-CDG (CDG-1d) Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Synthesis of substrates in N-glycan biosythesis Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Sialic acid metabolism Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CIC DCAF8 FAM60A GNE PARP11 PFKL PRPF3 PTAFR RIBC2	17 interactors: ADAMTSL4 CRMP1 GTPBP3 KIAA1549 KRT31 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP5-9 KRTAP9-2 NOTCH2NL RIF1 SPRY2 ZBTB16
Entrez ID		84705	10020
HPRD ID		12255	04825
Ensembl ID		ENSG00000130299	ENSG00000159921
Uniprot IDs		B7Z563 Q969Y2	H0YFA7 Q9Y223
PDB IDs			2YHW 2YHY 2YI1 3EO3
Enriched GO Terms of Interacting Partners?		Carbohydrate Phosphorylation N-acetylglucosamine Biosynthetic Process Fructose 1,6-bisphosphate Metabolic Process Inositol Trisphosphate Biosynthetic Process
Tagcloud ?			15s alphap competition contaminant doublet eif2 eif2alpha eif2b exchange gdp germ gtp guanine heme impairs inability insects interact lysates nucleotides p41 presumably residue reticulocyte unable unlike wg wheat x
Tagcloud (Difference) ?			15s alphap competition contaminant doublet eif2 eif2alpha eif2b exchange gdp germ gtp guanine heme impairs inability insects interact lysates nucleotides p41 presumably residue reticulocyte unable unlike wg wheat x
Tagcloud (Intersection) ?