GTPBP3 and ZNF69

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		GTPBP3	ZNF69
Name		GTP binding protein 3, mitochondrial	zinc finger protein 69
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Transferase Complex	Nucleus
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity TRNA 5-taurinomethyluridine Synthase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	TRNA Wobble Uridine Modification TRNA Modification TRNA Processing TRNA Methylation Mitochondrial TRNA Wobble Uridine Modification	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		tRNA modification in the mitochondrion	None
GWAS		Mitochondrial DNA copy number ( 30704525 )	Mean corpuscular hemoglobin ( 32888494 )
Novel Interactors		None recorded	1 novel interactors: SMARCA4
Interacting Genes		29 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD OGT PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774	12 interacting genes: CFTR FAM124B FRS3 GTPBP3 KATNAL1 KRT31 LMNA LMO3 MEOX2 P4HB SMARCD1 ZNF417
Entrez ID		84705	7620
HPRD ID		12255	11836
Ensembl ID		ENSG00000130299	ENSG00000198429
Uniprot IDs		B7Z563 Q969Y2	Q9UC07
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	NBAF Complex RSC-type Complex NpBAF Complex GBAF Complex Nuclear Matrix Nucleosome Disassembly Protein-DNA Complex Disassembly Isomerase Activity Regulation Of Nucleotide-excision Repair SWI/SNF Complex Regulation Of G0 To G1 Transition Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Chromosome Organization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Stem Cell Population Maintenance Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Myoblast Differentiation Positive Regulation Of Anion Channel Activity DNA Double-strand Break Attachment To Nuclear Envelope Epigenetic Regulation Of Gene Expression Structural Constituent Of Nuclear Lamina Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Procollagen-proline 4-dioxygenase Complex Regulation Of Stem Cell Population Maintenance Transcription Coactivator Activity Regulation Of Myoblast Differentiation Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway TRNA 5-taurinomethyluridine Synthase Activity Mitochondrial TRNA Wobble Uridine Modification Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of Mitotic Metaphase/anaphase Transition ATP Hydrolysis Activity Positive Regulation Of Double-strand Break Repair Structural Constituent Of Cytoskeleton Positive Regulation Of Enamel Mineralization Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Peptidyl-proline Hydroxylation Regulation Of Sister Chromatid Segregation Regulation Of Glucose Mediated Signaling Pathway Transepithelial Water Transport Lamin Filament Nuclear Pore Localization Somite Specification Procollagen-proline 4-dioxygenase Activity Nucleosome Array Spacer Activity Positive Regulation Of T Cell Differentiation