GTPBP3 and CCDC32

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GTPBP3	CCDC32
Description		GTP binding protein 3, mitochondrial	coiled-coil domain containing 32
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Transferase Complex	Clathrin-coated Pit Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity TRNA 5-taurinomethyluridine Synthase Activity	Protein Binding
	Biological Process	TRNA Wobble Uridine Modification TRNA Modification TRNA Processing TRNA Methylation Mitochondrial TRNA Wobble Uridine Modification	Cell Projection Organization Cilium Organization Head Development Regulation Of Clathrin-dependent Endocytosis
Pathways		tRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Mitochondrial DNA copy number ( 30704525)
Interacting Genes		29 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD OGT PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774	4 interacting genes: ANXA2 GTPBP3 HSPB1 POT1
Entrez ID		84705	90416
HPRD ID		12255	14473
Ensembl ID		ENSG00000130299	ENSG00000128891
Uniprot IDs		B7Z563 Q969Y2	H0YLI5 Q9BV29
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport AnxA2-p11 Complex PCSK9-AnxA2 Complex Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Cornified Envelope Negative Regulation Of Receptor Catabolic Process Positive Regulation Of Intracellular Cholesterol Transport Negative Regulation Of Protein Kinase C Signaling Protein Kinase C Inhibitor Activity Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding TRNA 5-taurinomethyluridine Synthase Activity Mitochondrial TRNA Wobble Uridine Modification Positive Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Plasma Membrane Repair Positive Regulation Of Intracellular Lipid Transport Telomeric D-loop Binding Telomere Assembly Myelin Sheath Adaxonal Region Regulation Of Protein Kinase C Signaling Single-stranded Telomeric DNA Binding Regulation Of Plasma Membrane Repair Osteoclast Development Regulation Of Intracellular Cholesterol Transport Regulation Of Intracellular Lipid Transport Phospholipase A2 Inhibitor Activity Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Phospholipase Inhibitor Activity Positive Regulation Of Plasminogen Activation Anterograde Axonal Protein Transport Telomerase Inhibitor Activity Nuclear Telomere Cap Complex Shelterin Complex Telomeric D-loop Disassembly DEAD/H-box RNA Helicase Binding Establishment Of Protein Localization To Telomere Macromolecule Biosynthetic Process G-rich Strand Telomeric DNA Binding Mitochondrial TRNA Modification Schmidt-Lanterman Incisure Telomeric Loop Disassembly Mitochondrial RNA Modification Positive Regulation Of Receptor Recycling Membrane Raft Assembly Protein Transport Along Microtubule Contractile Muscle Fiber
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