GTPBP3 and TBC1D3G

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GTPBP3	TBC1D3G
Description		GTP binding protein 3, mitochondrial	TBC1 domain family member 3G
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Transferase Complex	Endosome Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity TRNA 5-taurinomethyluridine Synthase Activity	GTPase Activator Activity Protein Binding
	Biological Process	TRNA Wobble Uridine Modification TRNA Modification TRNA Processing TRNA Methylation Mitochondrial TRNA Wobble Uridine Modification
Pathways		tRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Mitochondrial DNA copy number ( 30704525)	Blood protein levels ( 23696881) Body mass index ( 26426971)
Interacting Genes		29 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD OGT PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774	8 interacting genes: BAG3 BAG4 GEM GRB2 GTPBP3 MDFI PSMD2 ZRANB1
Entrez ID		84705	101060321
HPRD ID		12255
Ensembl ID		ENSG00000130299	ENSG00000260287
Uniprot IDs		B7Z563 Q969Y2	Q6DHY5 Q6IPX1
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Adenyl-nucleotide Exchange Factor Activity Positive Regulation Of Actin Filament Polymerization Regulation Of Protein Targeting To Mitochondrion Nucleus Guanyl-nucleotide Exchange Factor Adaptor Activity Negative Regulation Of MRNA Modification Positive Regulation Of Protein Polymerization Grb2-EGFR Complex Proteasome Storage Granule Protein-folding Chaperone Binding Autophagosome Organization Autophagosome Assembly TRNA 5-taurinomethyluridine Synthase Activity Mitochondrial TRNA Wobble Uridine Modification Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Establishment Of Protein Localization Protein K29-linked Deubiquitination Positive Regulation Of Aggrephagy Protein K33-linked Deubiquitination Positive Regulation Of Supramolecular Fiber Organization Neurotrophin TRKA Receptor Binding Vacuole Organization Aggresome Assembly Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
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