TBC1D7 and RPGRIP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TBC1D7	RPGRIP1
Gene Name		TBC1 domain family, member 7	retinitis pigmentosa GTPase regulator interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Membrane-bounded Vesicle Cytoplasmic Vesicle Ciliary Basal Body	Axoneme Photoreceptor Connecting Cilium
	Molecular Function	Rab GTPase Activator Activity Protein Binding Rab GTPase Binding	Protein Binding
	Biological Process	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of Rab GTPase Activity Activation Of Rho GTPase Activity Response To Growth Factor Negative Regulation Of Cilium Assembly	Visual Perception Eye Photoreceptor Cell Development Response To Stimulus Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APP BLZF1 GABARAPL1 HOOK1 IKBKG KRT19 LDOC1 LZTS2 MAP1LC3A NEDD4 NEDD4L RPGRIP1 SSNA1 TRAF4 TSC1 TSC2	24 interactors: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564
Entrez ID		51256	57096
HPRD ID		18165	05673
Ensembl ID		ENSG00000145979	ENSG00000092200
Uniprot IDs		Q5JPB9 Q9P0N9	Q96KN7
PDB IDs		3QWL
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Intracellular Transport Cytoplasmic Transport Cellular Localization Glucose Import Negative Regulation Of Sodium Ion Transport Vacuole Organization Negative Regulation Of Signal Transduction Negative Regulation Of Cell Size Negative Regulation Of Signaling Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Protein Kinase Activity Nucleophagy Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cellular Component Assembly Regulation Of Kinase Activity Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Potassium Ion Transmembrane Transporter Activity Response To Stimulus Mitochondrion Degradation Regulation Of Signal Transduction Negative Regulation Of TOR Signaling Membrane Organization Cell Communication Synapse Organization NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Organelle Assembly Regulation Of Protein Metabolic Process Organ Development Regulation Of Potassium Ion Transmembrane Transport Intracellular Receptor Signaling Pathway Organelle Disassembly Negative Regulation Of Insulin Receptor Signaling Pathway Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Signaling Autophagic Vacuole Assembly Viral Process Cell Surface Receptor Signaling Pathway Lysosomal Transport Regulation Of Protein Phosphorylation Neuromuscular Junction Development Regulation Of TOR Signaling Macroautophagy Nucleocytoplasmic Transport Nuclear Transport Regulation Of Cell Junction Assembly Cellular Response To Stimulus Cell Projection Organization	Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Fatty Acid Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Apoptotic Signaling Pathway Negative Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Negative Regulation Of Lipid Biosynthetic Process Photoreceptor Cell Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Androgen Receptor Activity Negative Regulation Of Lipid Metabolic Process Regulation Of Fatty Acid Metabolic Process Regulation Of Cellular Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Neural Retina Development Negative Regulation Of Cilium Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Eye Development Signal Transduction By P53 Class Mediator Amacrine Cell Differentiation Cellular Response To Indole-3-methanol
Tagcloud ?		2a akt anabolic bub2 cdc16 coimmunoprecipitated constant dephosphorylation homolog mechanistic modulator mtorc1 nutrients phosphorylates pp2a rapamycin redd1 repress represses repressor rheb ser stimulating thr tre2 tsc tsc1 tsc2 tuberous	ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cep76 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 tgl throw ttl
Tagcloud (Difference) ?		2a akt anabolic bub2 cdc16 coimmunoprecipitated constant dephosphorylation homolog mechanistic modulator mtorc1 nutrients phosphorylates pp2a rapamycin redd1 repress represses repressor rheb ser stimulating thr tre2 tsc tsc1 tsc2 tuberous	ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cep76 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 tgl throw ttl
Tagcloud (Intersection) ?