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FBN3 and GADD45A
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
FBN3
GADD45A
Gene Name
fibrillin 3
growth arrest and DNA-damage-inducible, alpha
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Proteinaceous Extracellular Matrix
Nucleus
Cytoplasm
Molecular Function
Extracellular Matrix Structural Constituent
Calcium Ion Binding
Core Promoter Binding
Protein Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Activation Of MAPKKK Activity
DNA Repair
Negative Regulation Of Protein Kinase Activity
Apoptotic Process
Cell Cycle Arrest
Centrosome Cycle
Signal Transduction In Response To DNA Damage
Positive Regulation Of Apoptotic Process
Positive Regulation Of JNK Cascade
Cellular Response To Mechanical Stimulus
Cellular Response To Ionizing Radiation
Positive Regulation Of P38MAPK Cascade
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Molecules associated with elastic fibres
Elastic fibre formation
Degradation of the extracellular matrix
Drugs
Diseases
GWAS
Protein-Protein Interactions
13 interactors:
ANXA7
BID
C11orf58
CDKN1A
DAZAP2
GADD45A
GSK3B
NUDT21
PIK3R3
RPN2
RPS6KA6
TK1
TSC22D1
65 interactors:
ADAP1
ASCC2
AURKA
BAG6
C14orf1
CCNB1
CDK1
CDK11A
CDKN1A
CENPB
CHD3
CLEC3B
DCTN2
DNAJC13
EEF1A1
EEF1G
FAM83D
FAS
FBN3
FTL
GADD45GIP1
GAPDH
GBP2
GNB2
HIST1H1A
HIST1H2AL
HIST2H2BE
HIST3H3
HIST4H4
IGHM
IGSF21
JMJD1C
KHSRP
LMO4
MAP3K4
MAPK14
MASP1
MDM2
MICAL1
MIDN
MPP1
NPM1
NRBP1
NUCB2
PCNA
PFKFB4
PPARA
PSMC3
PTN
PTPRK
QARS
RAI1
RBPJ
RPS2
RXRA
SH3GLB1
SPTBN4
SYNE4
TLE1
TP53
UBE2D1
UBR1
VIM
ZHX1
ZNF135
Entrez ID
84467
1647
HPRD ID
10538
00528
Ensembl ID
ENSG00000142449
ENSG00000116717
Uniprot IDs
Q75N90
A5JUZ3
P24522
PDB IDs
2KG4
Enriched GO Terms of Interacting Partners
?
Signal Transduction In Response To DNA Damage
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Negative Regulation Of Phosphorylation
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Apoptotic Process
Negative Regulation Of Kinase Activity
Regulation Of Phosphorylation
Positive Regulation Of Mitochondrion Organization
Cellular Response To Ionizing Radiation
Negative Regulation Of Transferase Activity
Regulation Of Apoptotic Process
Negative Regulation Of Protein Phosphorylation
Regulation Of Kinase Activity
Cellular Response To Heat
Regulation Of Phosphorus Metabolic Process
Response To Metal Ion
Fetal Process Involved In Parturition
Cellular Response To Stress
Regulation Of Cell Death
Apoptotic Signaling Pathway
Cellular Response To DNA Damage Stimulus
Cellular Response To Mechanical Stimulus
Response To Organic Substance
Response To Organic Cyclic Compound
DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Response To Hormone
Regulation Of Mitochondrion Organization
Negative Regulation Of Type B Pancreatic Cell Development
Skeletal Muscle Cell Proliferation
Superior Temporal Gyrus Development
Apoptotic Process
Protein Oligomerization
Regulation Of Intracellular Transport
Programmed Cell Death
Protein Tetramerization
Extrinsic Apoptotic Signaling Pathway
Response To External Stimulus
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Cell Death
Death
Phosphorylation
Intracellular Signal Transduction
Response To Heat
Signal Transduction By P53 Class Mediator
Response To Inorganic Substance
Re-entry Into Mitotic Cell Cycle
Regulation Of Metabolic Process
Cell Cycle
Cell Cycle Process
Regulation Of Gene Expression
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Cellular Response To Organic Substance
Regulation Of Protein Metabolic Process
Organelle Organization
DNA Packaging
DNA Conformation Change
Negative Regulation Of Cellular Metabolic Process
Apoptotic Process
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Chromosome Organization
Cell Aging
Protein Complex Assembly
Chromatin Organization
Negative Regulation Of Cell Cycle
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Cell Death
Death
Positive Regulation Of Protein Metabolic Process
Cell Cycle Checkpoint
Positive Regulation Of Cellular Protein Catabolic Process
Response To Organic Substance
DNA Damage Checkpoint
Chromatin Assembly Or Disassembly
Stress-induced Premature Senescence
Immune Response
Mitotic Cell Cycle Checkpoint
Positive Regulation Of Cellular Protein Metabolic Process
Signal Transduction In Response To DNA Damage
Negative Regulation Of Gene Expression
Mitotic DNA Damage Checkpoint
Immune System Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Cell Death
Positive Regulation Of Metabolic Process
Innate Immune Response
Mitotic DNA Integrity Checkpoint
Response To Toxic Substance
Positive Regulation Of Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Proteolysis
Cellular Response To Oxygen Levels
Tagcloud
?
2h5
accompanies
anova
dynactin
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Difference)
?
2h5
accompanies
anova
dynactin
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Intersection)
?