FBN3 and C11orf58

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		FBN3	C11orf58
Gene Name		fibrillin 3	chromosome 11 open reading frame 58
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix	Cellular_component
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding	Molecular_function
	Biological Process		Biological_process
Pathways		Molecules associated with elastic fibres Elastic fibre formation Degradation of the extracellular matrix
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ANXA7 BID C11orf58 CDKN1A DAZAP2 GADD45A GSK3B NUDT21 PIK3R3 RPN2 RPS6KA6 TK1 TSC22D1	16 interactors: A2M EEF1G FBN3 KIAA1377 MBTPS1 POLR2C PTN RNF19A RPLP1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP TRA2A ZBTB48
Entrez ID		84467	10944
HPRD ID		10538	18069
Ensembl ID		ENSG00000142449
Uniprot IDs		Q75N90	O00193
PDB IDs
Enriched GO Terms of Interacting Partners?		Signal Transduction In Response To DNA Damage Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Negative Regulation Of Phosphorylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Protein Kinase Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Mitochondrion Organization Cellular Response To Ionizing Radiation Negative Regulation Of Transferase Activity Regulation Of Apoptotic Process Negative Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Cellular Response To Heat Regulation Of Phosphorus Metabolic Process Response To Metal Ion Fetal Process Involved In Parturition Cellular Response To Stress Regulation Of Cell Death Apoptotic Signaling Pathway Cellular Response To DNA Damage Stimulus Cellular Response To Mechanical Stimulus Response To Organic Substance Response To Organic Cyclic Compound DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Reactive Oxygen Species Metabolic Process Response To Hormone Regulation Of Mitochondrion Organization Negative Regulation Of Type B Pancreatic Cell Development Skeletal Muscle Cell Proliferation Superior Temporal Gyrus Development Apoptotic Process Protein Oligomerization Regulation Of Intracellular Transport Programmed Cell Death Protein Tetramerization Extrinsic Apoptotic Signaling Pathway Response To External Stimulus Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Death Death Phosphorylation Intracellular Signal Transduction Response To Heat Signal Transduction By P53 Class Mediator Response To Inorganic Substance Re-entry Into Mitotic Cell Cycle	MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity RNA Splicing Negative Regulation Of Complement Activation, Lectin Pathway Endoplasmic Reticulum Unfolded Protein Response
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