FBN3 and DAZAP2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		FBN3	DAZAP2
Description		fibrillin 3	DAZ associated protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Microfibril Extracellular Region Extracellular Matrix	Nucleus Cytoplasm Cytoplasmic Stress Granule Nuclear Body Nuclear Speck Protein-containing Complex
	Molecular Function	Hormone Activity Extracellular Matrix Structural Constituent Calcium Ion Binding Extracellular Matrix Constituent Conferring Elasticity	P53 Binding Transcription Coactivator Activity Protein Binding Receptor Tyrosine Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity WW Domain Binding Protein Serine/threonine Kinase Binding DNA-binding Transcription Factor Binding
	Biological Process	Glucose Metabolic Process Signal Transduction Glucose Homeostasis Camera-type Eye Development Embryonic Eye Morphogenesis	Protein Destabilization Stress Granule Assembly Positive Regulation Of DNA-templated Transcription
Pathways		Degradation of the extracellular matrix Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Attention deficit hyperactivity disorder ( 30563984) Macular telangiectasia type 2 ( 33654266) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399) Pre-treatment viral load in HIV-1 infection ( 31219150) Refractive error ( 32231278) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		13 interacting genes: ANXA7 BID C11orf58 CDKN1A DAZAP2 GADD45A GSK3B NUDT21 PIK3R3 RPN2 RPS6KA6 TK1 TSC22D1	168 interacting genes: AATF ACOT7 AOC1 ARID5A ATXN1 ATXN1L BAG3 BATF2 BHLHE40 C1orf94 CALCOCO2 CAMK2A CAPN15 CCDC120 CDK4 CELF5 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 DESI1 DTX2 EPN1 EPN2 EPN3 ESRP1 EXD3 FAM168A FAM83A FBN3 FOXH1 GGA3 GPS2 GPSM1 HEY1 HGS HIP1 HIPK2 INCA1 KLHL42 KRTAP19-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 LGALS9 LITAF LMO2 MAGED1 MAPK1IP1L MED31 MINDY1 MINDY3 MTURN MYEOV MYOZ3 NDUFA5 NEDD4 NEDD4L NOC4L NOTCH1 OPTN OTUB2 OTUD7B OTULIN PATZ1 PDIK1L PEF1 PITX2 PLEKHB2 PLEKHF2 PLSCR1 PLSCR4 POGZ POLI PROP1 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PRR34 RABGEF1 RAD18 RAD23A RAMAC RBFOX1 RBFOX2 RBM11 RBM24 RBM43 RBPMS RHOXF2 RNF115 RNF208 RNF44 ROR2 RPS27A RUNX1 SEPTIN2 SIAH1 SMAP2 SMURF2 SNRPC SOX10 SOX6 SPMIP9 SQSTM1 STAM2 STAT6 TAX1BP1 TBX6 TCF7L2 TENT5B TENT5C TFG TIAL1 TLE1 TLE5 TNIP1 TNIP3 TOLLIP TOM1 TP53 UBA52 UBAC1 UBAP2 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBE2E3 UBE2V1 UBE3A UBQLN1 UBQLN2 UBQLN4 UBXN6 UBXN7 USP13 USP5 VENTX VEZF1 VHLL VPS37C WDR73 WWOX WWP1 YOD1 ZBTB32 ZC3H10 ZFAND2A ZFAND2B ZFYVE9 ZNF34 ZNF581
Entrez ID		84467	9802
HPRD ID		10538	08463
Ensembl ID		ENSG00000142449	ENSG00000183283
Uniprot IDs		A0A494C0D8 A8KAY2 Q75N90	Q15038
PDB IDs
Enriched GO Terms of Interacting Partners?		Signal Transduction In Response To DNA Damage Positive Regulation Of Programmed Cell Death Ubiquitin Protein Ligase Binding Nuclear Body Protein Serine/threonine Kinase Binding Positive Regulation Of Membrane Permeability Positive Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Catalytic Activity Regulation Of Programmed Cell Death Negative Regulation Of Developmental Process Cysteine-type Endopeptidase Regulator Activity Involved In Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Apoptotic Process Intracellular Signal Transduction Apoptotic Signaling Pathway Regulation Of Membrane Permeability Negative Regulation Of Kinase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Reactive Oxygen Species Metabolic Process PCNA-p21 Complex Cell Cycle G1/S Phase Transition Negative Regulation Of Cardiac Muscle Tissue Regeneration G1/S Transition Of Mitotic Cell Cycle Cellular Response To Ionizing Radiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein P53 Binding Superior Temporal Gyrus Development TOR Signaling Negative Regulation Of Type B Pancreatic Cell Development Regulation Of Stem Cell Differentiation Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Microtubule Anchoring At Centrosome Insulin Receptor Signaling Pathway Thymidine Kinase Activity Positive Regulation Of Pro-B Cell Differentiation Negative Regulation Of Embryonic Development DNA Damage Response Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction DNA Synthesis Involved In Mitotic DNA Replication Protein Tetramerization Positive Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Mesoderm Development Signal Transduction By P53 Class Mediator Regulation Of Apoptotic Process Negative Regulation Of Protein Phosphorylation Cellular Response To Cell-matrix Adhesion Negative Regulation Of TORC2 Signaling Negative Regulation Of Dopaminergic Neuron Differentiation	Protein Binding Polyubiquitin Modification-dependent Protein Binding Post-translational Protein Modification Ubiquitin Binding Nucleus Protein Ubiquitination Protein Modification By Small Protein Conjugation Nucleoplasm Modification-dependent Protein Catabolic Process Proteolysis Proteolysis Involved In Protein Catabolic Process Autophagy Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process K48-linked Deubiquitinase Activity Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Catabolic Process Cytoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin-dependent Protein Catabolic Process Cysteine-type Deubiquitinase Activity Positive Regulation Of Metabolic Process Macroautophagy Protein K48-linked Deubiquitination Negative Regulation Of Signal Transduction Cysteine-type Peptidase Activity Protein Modification Process Ubiquitin-protein Transferase Activity Protein K63-linked Ubiquitination Negative Regulation Of Transcription By RNA Polymerase II Ubiquitin Protein Ligase Binding Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Protein Tag Activity Protein Metabolic Process Identical Protein Binding Cytosol Autophagosome Negative Regulation Of DNA-templated Transcription Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Modification By Small Protein Removal Clathrin Binding Negative Regulation Of RNA Biosynthetic Process Regulation Of Macroautophagy Establishment Of Protein Localization To Vacuole
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