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FBN3 and RPN2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
FBN3
RPN2
Gene Name
fibrillin 3
ribophorin II
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Proteinaceous Extracellular Matrix
Autophagic Vacuole Membrane
Nucleus
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Rough Endoplasmic Reticulum
Oligosaccharyltransferase Complex
Membrane
Integral Component Of Membrane
Molecular Function
Extracellular Matrix Structural Constituent
Calcium Ion Binding
Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity
Ribosome Binding
Biological Process
Translation
Cellular Protein Modification Process
SRP-dependent Cotranslational Protein Targeting To Membrane
Aging
Gene Expression
Protein N-linked Glycosylation Via Asparagine
Response To Drug
Post-translational Protein Modification
Cellular Protein Metabolic Process
Pathways
Molecules associated with elastic fibres
Elastic fibre formation
Degradation of the extracellular matrix
Defective ALG2 causes ALG2-CDG (CDG-1i)
Diseases of glycosylation
Translation
Defective ALG3 causes ALG3-CDG (CDG-1d)
Post-translational protein modification
SRP-dependent cotranslational protein targeting to membrane
Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
Defective MGAT2 causes MGAT2-CDG (CDG-2a)
Defective ALG1 causes ALG1-CDG (CDG-1k)
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective RFT1 causes RFT1-CDG (CDG-1n)
Defective ALG6 causes ALG6-CDG (CDG-1c)
Defective MOGS causes MOGS-CDG (CDG-2b)
Asparagine N-linked glycosylation
Defective ALG8 causes ALG8-CDG (CDG-1h)
Defective ALG9 causes ALG9-CDG (CDG-1l)
Defective MAN1B1 causes MRT15
Defective MPDU1 causes MPDU1-CDG (CDG-1f)
Defective ALG12 causes ALG12-CDG (CDG-1g)
Diseases associated with N-glycosylation of proteins
Defective ALG11 causes ALG11-CDG (CDG-1p)
Drugs
Diseases
GWAS
Hippocampal atrophy (
19668339
)
Protein-Protein Interactions
13 interactors:
ANXA7
BID
C11orf58
CDKN1A
DAZAP2
GADD45A
GSK3B
NUDT21
PIK3R3
RPN2
RPS6KA6
TK1
TSC22D1
8 interactors:
ADRM1
EZH2
FBN3
NDRG1
NGFR
RBBP4
RCHY1
RHOA
Entrez ID
84467
6185
HPRD ID
10538
01609
Ensembl ID
ENSG00000142449
ENSG00000118705
Uniprot IDs
Q75N90
P04844
PDB IDs
Enriched GO Terms of Interacting Partners
?
Signal Transduction In Response To DNA Damage
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Negative Regulation Of Phosphorylation
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Apoptotic Process
Negative Regulation Of Kinase Activity
Regulation Of Phosphorylation
Positive Regulation Of Mitochondrion Organization
Cellular Response To Ionizing Radiation
Negative Regulation Of Transferase Activity
Regulation Of Apoptotic Process
Negative Regulation Of Protein Phosphorylation
Regulation Of Kinase Activity
Cellular Response To Heat
Regulation Of Phosphorus Metabolic Process
Response To Metal Ion
Fetal Process Involved In Parturition
Cellular Response To Stress
Regulation Of Cell Death
Apoptotic Signaling Pathway
Cellular Response To DNA Damage Stimulus
Cellular Response To Mechanical Stimulus
Response To Organic Substance
Response To Organic Cyclic Compound
DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Response To Hormone
Regulation Of Mitochondrion Organization
Negative Regulation Of Type B Pancreatic Cell Development
Skeletal Muscle Cell Proliferation
Superior Temporal Gyrus Development
Apoptotic Process
Protein Oligomerization
Regulation Of Intracellular Transport
Programmed Cell Death
Protein Tetramerization
Extrinsic Apoptotic Signaling Pathway
Response To External Stimulus
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Cell Death
Death
Phosphorylation
Intracellular Signal Transduction
Response To Heat
Signal Transduction By P53 Class Mediator
Response To Inorganic Substance
Re-entry Into Mitotic Cell Cycle
Regulation Of Cell Cycle
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Negative Regulation Of Axonogenesis
Regulation Of Epidermis Development
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Axonogenesis
Regulation Of Cell Morphogenesis
Regulation Of Cell Cycle Process
Positive Regulation Of Cell Development
Negative Regulation Of Cell Morphogenesis Involved In Differentiation
Regulation Of Cell Proliferation
Negative Regulation Of Neuron Projection Development
Neurogenesis
Regulation Of Proteolysis
Negative Regulation Of Cell Projection Organization
Regulation Of Neurogenesis
Negative Regulation Of Hair Follicle Development
Skeletal Muscle Satellite Cell Migration
Regulation Of Axonogenesis
Negative Regulation Of Cell Differentiation
Negative Regulation Of Hair Cycle
Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration
Positive Regulation Of Odontogenesis Of Dentin-containing Tooth
Negative Regulation Of Neuron Differentiation
Regulation Of Cell Development
Positive Regulation Of Cell Differentiation
Regulation Of Gene Expression, Epigenetic
Neurotrophin TRK Receptor Signaling Pathway
Apolipoprotein A-I-mediated Signaling Pathway
Positive Regulation Of Neuron Projection Development
Positive Regulation Of Cell Cycle Process
Neurotrophin Signaling Pathway
Positive Regulation Of Spindle Checkpoint
Cleavage Furrow Formation
Regulation Of Protein Metabolic Process
Central Nervous System Development
Nervous System Development
G1 To G0 Transition
Protein Complex Assembly
Cell Cycle Process
DNA Replication-dependent Nucleosome Assembly
Positive Regulation Of Cell Projection Organization
Positive Regulation Of Cell Cycle
Negative Regulation Of Epidermal Cell Differentiation
Positive Regulation Of Cell Cycle Checkpoint
Proteasome Assembly
Histone H3-K27 Methylation
Negative Regulation Of Neurogenesis
Positive Regulation Of Proteolysis
Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
acc1
adp1
aids
albicans
antiretroviral
candida
candidiasis
decades
diploid
divergence
epidemiology
fluconazole
gln4
haart
heterozygous
immunocompromised
iran
iranian
isolate
loci
mlst
multilocus
phylogeny
polymorphic
scheme
sya1
typed
typing
vps13
Tagcloud (Difference)
?
acc1
adp1
aids
albicans
antiretroviral
candida
candidiasis
decades
diploid
divergence
epidemiology
fluconazole
gln4
haart
heterozygous
immunocompromised
iran
iranian
isolate
loci
mlst
multilocus
phylogeny
polymorphic
scheme
sya1
typed
typing
vps13
Tagcloud (Intersection)
?