BYSL and WASF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BYSL	WASF3
Description		bystin like	WASP family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol Membrane Preribosome, Small Subunit Precursor Apical Part Of Cell	Cytoplasm Cytoskeleton Lamellipodium SCAR Complex Extracellular Exosome Glial Cell Projection Postsynapse Glutamatergic Synapse
	Molecular Function	RNA Binding Protein Binding SnoRNA Binding	Actin Binding Protein Binding Protein Kinase A Regulatory Subunit Binding Arp2/3 Complex Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) In Utero Embryonic Development Blastocyst Formation Trophectodermal Cell Differentiation RRNA Processing Ribosome Biogenesis Stem Cell Proliferation Regulation Of Protein Localization To Nucleolus	Cytoskeleton Organization Regulation Of Cell Shape Oligodendrocyte Development Lamellipodium Assembly Actin Cytoskeleton Organization Actin Filament Polymerization Positive Regulation Of Myelination Protein-containing Complex Assembly Modification Of Postsynaptic Actin Cytoskeleton Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs RAC1 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 19862010 20139978) Mean corpuscular volume ( 19862010 20139978 23263863) Menarche (age at onset) ( 25231870 27182965) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Red blood cell count ( 20139978)	Hallux valgus ( 32131869) Left-handedness ( 32989287) Metabolite levels ( 23823483) Platelet distribution width ( 32888494) Sporadic pituitary adenoma ( 26029870) Systolic blood pressure ( 30224653)
Interacting Genes		138 interacting genes: AIMP2 AMOTL2 APP ATP5F1B AXIN2 BEND7 BFSP1 BHLHE40 C1orf94 CAVIN4 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 DRC4 DVL2 EAPP EIF4ENIF1 EMD EPS8 FAM228A FAM9B FCHO1 FXR1 FXR2 GMCL1 GOLGA2 GOLGA6L9 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF1 IKZF3 JRK KATNAL1 KIFC3 KLHL2 KLHL6 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LDOC1 LHX3 LMNA LMO1 LMO2 LONRF1 LZTS1 LZTS2 MB21D2 MCIDAS MEOX1 MEOX2 MID1 MID2 MIPOL1 MKRN1 MRFAP1L1 MTUS2 NECAB2 NF2 OGT OLIG3 OSBPL3 PDE4DIP PHC2 PICK1 PIH1D1 PNMA1 PNMA2 PRICKLE1 PSMC6 RACGAP1 RALY RALYL RBAK RP9 RUBCN SMN1 SMN2 SNW1 SSX2IP STX11 TBC1D26 TEKT1 TFIP11 THAP1 TLE5 TNIP1 TRAF2 TRAF4 TRAK1 TRIM14 TRIM27 TRIM37 TRIM38 TRIM41 TRIM54 TRIM55 TRIP6 TRO TROAP USH1G USO1 VIM VPS37B VPS52 WASF3 WTAP ZBTB14 ZBTB8A ZC2HC1C ZFP64 ZMAT5 ZNF212 ZNF286A ZNF426 ZNF438 ZNF48 ZNF655 ZNF668 ZNF71 ZNF835 ZSCAN22	12 interacting genes: ABI2 ACTB ACTR3 BYSL CAMK2D CKS1B EGFR KANK2 KIFC3 PIK3R1 PIK3R2 RASAL3
Entrez ID		705	10810
HPRD ID		04848	05458
Ensembl ID		ENSG00000112578	ENSG00000132970
Uniprot IDs		Q13895	Q5T8P4 Q9UPY6
PDB IDs		6G18 6G4S 6G4W 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Microtubule Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Intermediate Filament Microtubule Binding Cytoplasm Cytoskeleton Regulation Of Primary Metabolic Process Negative Regulation Of RNA Metabolic Process Keratin Filament Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Cytosol Fibrillar Center TORC1 Complex Assembly Cellular Response To Muramyl Dipeptide Regulation Of Gene Expression Microtubule-based Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Organelle Organization Ubiquitin Protein Ligase Activity Cajal Body Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Segment Specification Negative Regulation Of Viral Transcription Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cytoskeleton Organization Regulation Of Viral Transcription Centrosome Cycle Microtubule Organizing Center Organization Nuclear Pore Localization Transcription Coactivator Activity Somite Specification Cytoplasmic Ribonucleoprotein Granule Response To Muramyl Dipeptide Supramolecular Fiber Organization Positive Regulation Of Nucleobase-containing Compound Metabolic Process	Regulation Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization To Membrane Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Lamellipodium Organization Regulation Of Lamellipodium Assembly Adherens Junction Organization Regulation Of Lamellipodium Organization 1-phosphatidylinositol-3-kinase Regulator Activity Regulation Of Cellular Localization Regulation Of Protein Localization Phosphatidylinositol 3-kinase Complex, Class IA Phosphatidylinositol 3-kinase Regulatory Subunit Binding Regulation Of Actin Filament Organization Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cell Motility Protein Phosphatase Binding Adherens Junction Assembly Regulation Of Cellular Component Organization Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament-based Process Focal Adhesion Regulation Of Protein Localization To Nucleus Regulation Of G1/S Transition Of Mitotic Cell Cycle Intracellular Signaling Cassette Cell-cell Junction Organization Regulation Of Cell Cycle G1/S Phase Transition Adherens Junction Lamellipodium Regulation Of Mitotic Cell Cycle Cell-cell Junction Positive Regulation Of Protein Import Into Nucleus Regulation Of Cytoskeleton Organization Regulation Of Transcription By RNA Polymerase II Phosphotyrosine Residue Binding Regulation Of Cell Projection Assembly Positive Regulation Of Norepinephrine Uptake Identical Protein Binding Cellular Response To Cytochalasin B Multivesicular Body, Internal Vesicle Lumen GTPase Activator Activity Brush Border Regulation Of Protein Import Into Nucleus Regulation Of Organelle Organization Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Norepinephrine Uptake Positive Regulation Of Protein Localization To Cell Periphery
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?