SVIL and LMNB2

Number of citations of the paper that reports this interaction (PMID 20309963)
11

Data Source:
BioGRID (two hybrid)

		SVIL	LMNB2
Gene Name		supervillin	lamin B2
Image
Gene Ontology Annotations	Cellular Component	Podosome Nucleus Cytoplasm Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere Invadopodium	Nuclear Inner Membrane Lamin Filament
	Molecular Function	Protein Binding Actin Filament Binding	Molecular_function Structural Molecule Activity
	Biological Process	Cytoskeleton Organization Skeletal Muscle Tissue Development Positive Regulation Of Cytokinesis	Biological_process
Pathways
Drugs
Diseases
GWAS		Normalized brain volume ( 19010793)
Protein-Protein Interactions		37 interactors: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LIMA1 LMNA LMNB2 LUC7L2 MIF4GD MKL2 MPHOSPH9 NME2 NR3C1 ODF2 P2RX7 PAN3 PCNXL3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG	3 interactors: PRKCD SVIL TMPO
Entrez ID		6840	84823
HPRD ID		04992	01037
Ensembl ID		ENSG00000197321	ENSG00000176619
Uniprot IDs		O95425 Q569J5	J9JID7 Q03252
PDB IDs		2K6M 2K6N	2LLL
Enriched GO Terms of Interacting Partners?		Organelle Organization Regulation Of Cellular Component Organization Mitotic Cell Cycle Process Regulation Of Organelle Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Mitotic Nuclear Division Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Component Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Nitrogen Compound Metabolic Process Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Positive Regulation Of Gene Expression Establishment Of Organelle Localization Apoptotic Process Transcription, DNA-templated Programmed Cell Death Regulation Of Signaling Microtubule-based Process Steroid Hormone Mediated Signaling Pathway Developmental Process Cell Death Death Establishment Of Localization In Cell RNA Biosynthetic Process Metaphase Plate Congression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Positive Regulation Of Organelle Organization Transcription From RNA Polymerase II Promoter Response To Organic Substance G2/M Transition Of Mitotic Cell Cycle Organelle Localization Heterocycle Metabolic Process Establishment Of Protein Localization Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process	Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Interleukin-10 Production Negative Regulation Of Filopodium Assembly Interleukin-12 Production Positive Regulation Of Ceramide Biosynthetic Process Regulation Of Ceramide Biosynthetic Process Positive Regulation Of Phospholipid Transport Negative Regulation Of Platelet Aggregation Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Superoxide Anion Generation Regulation Of Platelet Aggregation Negative Regulation Of Platelet Activation Positive Regulation Of Protein Dephosphorylation Neutrophil Activation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Lipid Catabolic Process Regulation Of Platelet Activation Cellular Senescence Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cytokinesis B Cell Proliferation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Filopodium Assembly Peptidyl-threonine Phosphorylation Positive Regulation Of Dephosphorylation Activation Of Phospholipase C Activity Negative Regulation Of Blood Coagulation Negative Regulation Of Protein Binding Positive Regulation Of Phospholipase C Activity Positive Regulation Of Transporter Activity Regulation Of Lipid Catabolic Process Regulation Of Cytokinesis Negative Regulation Of Coagulation Positive Regulation Of Lipid Transport Positive Regulation Of Lipid Biosynthetic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Wound Healing Positive Regulation Of Response To DNA Damage Stimulus Termination Of Signal Transduction Cell Aging Negative Regulation Of Actin Filament Polymerization Execution Phase Of Apoptosis Positive Regulation Of Phospholipase Activity Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of MAP Kinase Activity
Tagcloud ?		10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin
Tagcloud (Difference) ?		10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin
Tagcloud (Intersection) ?