SVIL and MIF4GD

Number of citations of the paper that reports this interaction (PMID 20309963)
11

Data Source:
BioGRID (two hybrid)

		SVIL	MIF4GD
Gene Name		supervillin	MIF4G domain containing
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Podosome Nucleus Cytoplasm Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere Invadopodium	Nucleolus Cytoplasm
	Molecular Function	Protein Binding Actin Filament Binding	RNA Binding Protein Binding Protein C-terminus Binding
	Biological Process	Cytoskeleton Organization Skeletal Muscle Tissue Development Positive Regulation Of Cytokinesis	Regulation Of Translation
Pathways
Drugs
Diseases
GWAS		Normalized brain volume ( 19010793)
Protein-Protein Interactions		37 interactors: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LIMA1 LMNA LMNB2 LUC7L2 MIF4GD MKL2 MPHOSPH9 NME2 NR3C1 ODF2 P2RX7 PAN3 PCNXL3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG	10 interactors: DDX19A DDX19B EXOSC6 HDAC4 HGS HINFP PDE4DIP PPARG SVIL UBQLN4
Entrez ID		6840	57409
HPRD ID		04992	10629
Ensembl ID		ENSG00000197321	ENSG00000125457
Uniprot IDs		O95425 Q569J5	A9UHW6 J3KSB8
PDB IDs		2K6M 2K6N
Enriched GO Terms of Interacting Partners?		Organelle Organization Regulation Of Cellular Component Organization Mitotic Cell Cycle Process Regulation Of Organelle Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Mitotic Nuclear Division Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Component Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Nitrogen Compound Metabolic Process Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Positive Regulation Of Gene Expression Establishment Of Organelle Localization Apoptotic Process Transcription, DNA-templated Programmed Cell Death Regulation Of Signaling Microtubule-based Process Steroid Hormone Mediated Signaling Pathway Developmental Process Cell Death Death Establishment Of Localization In Cell RNA Biosynthetic Process Metaphase Plate Congression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Positive Regulation Of Organelle Organization Transcription From RNA Polymerase II Promoter Response To Organic Substance G2/M Transition Of Mitotic Cell Cycle Organelle Localization Heterocycle Metabolic Process Establishment Of Protein Localization Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process	Establishment Of Protein Localization Response To Metformin Response To Diuretic Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Protein Localization Cellular Response To Vitamin E Regulation Of Cholesterol Transporter Activity MRNA Transport RNA Transport RNA Localization Protein Transport B Cell Activation Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Receptor Biosynthetic Process Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Gene Expression Immune System Development Cellular Response To Hyperoxia Receptor Biosynthetic Process Negative Regulation Of Multicellular Organismal Metabolic Process Negative Regulation Of Sequestering Of Triglyceride Negative Regulation Of Cholesterol Storage Negative Regulation Of Glycolytic Process Peptidyl-lysine Deacetylation Response To Denervation Involved In Regulation Of Muscle Adaptation Negative Regulation Of Telomerase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA Deamination Response To Inactivity Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cellular Response To Prostaglandin E Stimulus Protein Targeting To Lysosome Negative Regulation Of Acute Inflammatory Response Negative Regulation Of Myotube Differentiation Regulation Of Telomerase Activity Response To Low-density Lipoprotein Particle Positive Regulation Of Protein Sumoylation Positive Regulation Of Phagocytosis, Engulfment Protein Localization To Lysosome Cellular Response To Lithium Ion Positive Regulation Of Fatty Acid Oxidation White Fat Cell Differentiation Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Receptor Biosynthetic Process Cellular Response To Prostaglandin Stimulus Response To Prostaglandin E
Tagcloud ?		10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin	bub1 cenexin cytokinesis eplin flightless flna furrow g6 gelsolin hax1 headpiece interactors kif14 kif16a kifc3 kinesin lima1 midbody odf2 overlaps predominately rhamm sh3pxd2a slip1 stard9 supervillin tks5 tnfaip1 villin
Tagcloud (Difference) ?		10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland hela identity message microvilli nh2 originally s3 salivary sw480 terminus tightly	bub1 cenexin cytokinesis eplin flightless flna furrow g6 gelsolin hax1 interactors kif14 kif16a kifc3 kinesin lima1 midbody odf2 overlaps predominately rhamm sh3pxd2a slip1 stard9 tks5 tnfaip1
Tagcloud (Intersection) ?		headpiece supervillin villin