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SVIL and ODF2
Number of citations of the paper that reports this interaction (PubMedID
20309963
)
81
Data Source:
BioGRID
(two hybrid)
SVIL
ODF2
Description
supervillin
outer dense fiber of sperm tails 2
Image
No pdb structure
GO Annotations
Cellular Component
Podosome
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Focal Adhesion
Actin Cytoskeleton
Membrane
Midbody
Cleavage Furrow
Microtubule Minus-end
Cell Projection
Costamere
Anchoring Junction
Spindle Pole
Nucleus
Cytoplasm
Centrosome
Centriole
Cytosol
Cytoskeleton
Microtubule
Cilium
Microtubule Cytoskeleton
Motile Cilium
Ciliary Basal Body
Sperm Flagellum
Cell Projection
Sperm Midpiece
Sperm Principal Piece
Centriolar Subdistal Appendage
Molecular Function
Actin Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Actin Filament Binding
Structural Molecule Activity
Protein Binding
Small GTPase Binding
Biological Process
Cytoskeleton Organization
Skeletal Muscle Tissue Development
Actin Polymerization Or Depolymerization
Positive Regulation Of Cytokinesis
Actin Filament Severing
Barbed-end Actin Filament Capping
Muscle Structure Development
Spermatogenesis
Intracellular Protein Localization
Centriole-centriole Cohesion
Cell Differentiation
Cilium Organization
Regulation Of Cilium Assembly
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Age-related cognitive decline (language) (slope of z-scores) (
30954325
)
Bone fracture in osteoporosis (
28580392
)
Dilated cardiomyopathy (
33495596
)
Dilated cardiomyopathy (MTAG) (
33495596
)
Estimated glomerular filtration rate (
31152163
)
Lung function (FEV1/FVC) (
28166213
)
Metabolite levels (
23823483
)
Neurofibrillary tangles (
25188341
)
Normalized brain volume (
19010793
)
Platelet thrombus formation (
22550155
)
Plateletcrit (
32888494
)
Body mass index (
26426971
)
Interacting Genes
36 interacting genes:
AR
ATRX
BUB1
CENPF
DYNLT1
ESR1
FLNA
HAX1
HMMR
HSP90AA1
ITGB3BP
KIF22
KIFC3
KMT2A
KRT18
LMNA
LMNB2
LUC7L2
MIF4GD
MPHOSPH9
MRTFB
NME2
NR3C1
ODF2
P2RX7
PAN3
PCNX3
PPARG
SH3PXD2A
STARD9
TGFB1I1
TMEM132D
TNFAIP1
TRIP6
UXT
YWHAG
17 interacting genes:
APP
FBXO25
ING5
LRRK1
MAP3K1
MARK4
MEOX2
NRIP1
ODF1
RAB8A
SMURF1
SNW1
SVIL
TRAF5
TRIM55
TRIM63
ZDHHC17
Entrez ID
6840
4957
HPRD ID
04992
03601
Ensembl ID
ENSG00000197321
ENSG00000136811
Uniprot IDs
A0A6I8PIX7
O95425
Q569J5
A0A024R8A5
A0A8J8YVX4
A0A8J8Z1C3
B3KSD5
B4DUU0
B4DX03
B4DX85
Q5BJF6
PDB IDs
2K6M
2K6N
Enriched GO Terms of Interacting Partners
?
Organelle Organization
Regulation Of MiRNA Transcription
Regulation Of MiRNA Metabolic Process
Estrogen Response Element Binding
Cytoskeleton
Identical Protein Binding
Nucleus
Regulation Of Organelle Organization
Nuclear Receptor Activity
Positive Regulation Of MiRNA Transcription
Positive Regulation Of MiRNA Metabolic Process
Cytoplasm
Regulation Of Apoptotic Process
Steroid Binding
Regulation Of Programmed Cell Death
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Pore Localization
Chromatin Binding
Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Receptor-mediated Signaling Pathway
Apoptotic Process
Regulation Of Cellular Component Organization
Positive Regulation Of Macromolecule Metabolic Process
Cytosol
Cell Death
Programmed Cell Death
Nitric-oxide Synthase Regulator Activity
Positive Regulation Of Macromolecule Biosynthetic Process
Spindle
Regulation Of Gene Expression
Regulation Of Chromosome Organization
Nuclear Matrix
Cytoskeleton Organization
Prostate Gland Growth
Positive Regulation Of Biosynthetic Process
Regulation Of Macromolecule Biosynthetic Process
Intracellular Protein Localization
Chromosome Segregation
Microtubule Binding
Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Microtubule-based Process
Microtubule Motor Activity
Hormone-mediated Signaling Pathway
Regulation Of Primary Metabolic Process
Positive Regulation Of Metabolic Process
Response To Estrogen
Chromatin Organization
Nuclear Lamina
Microtubule Cytoskeleton Organization
Negative Regulation Of Apoptotic Process
Protein Modification Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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