SVIL and KIF22

Number of citations of the paper that reports this interaction (PMID 20309963)
11

Data Source:
BioGRID (two hybrid)

		SVIL	KIF22
Gene Name		supervillin	kinesin family member 22
Image
Gene Ontology Annotations	Cellular Component	Podosome Nucleus Cytoplasm Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere Invadopodium	Kinetochore Chromatin Nucleus Nucleoplasm Cytoplasm Spindle Cytosol Kinesin Complex Microtubule Focal Adhesion
	Molecular Function	Protein Binding Actin Filament Binding	DNA Binding Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Cytoskeleton Organization Skeletal Muscle Tissue Development Positive Regulation Of Cytokinesis	DNA Repair Microtubule-based Movement Sister Chromatid Cohesion Mitotic Nuclear Division Mitotic Metaphase Plate Congression Blood Coagulation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways			MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS		Normalized brain volume ( 19010793)	Red blood cell traits ( 23222517)
Protein-Protein Interactions		37 interactors: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LIMA1 LMNA LMNB2 LUC7L2 MIF4GD MKL2 MPHOSPH9 NME2 NR3C1 ODF2 P2RX7 PAN3 PCNXL3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG	6 interactors: ATXN1 GDF9 IMMT PJA1 SIAH1 SVIL
Entrez ID		6840	3835
HPRD ID		04992	04445
Ensembl ID		ENSG00000197321	ENSG00000079616
Uniprot IDs		O95425 Q569J5	B7Z9T5 Q14807
PDB IDs		2K6M 2K6N	2EDU 3BFN
Enriched GO Terms of Interacting Partners?		Organelle Organization Regulation Of Cellular Component Organization Mitotic Cell Cycle Process Regulation Of Organelle Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Mitotic Nuclear Division Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Component Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Nitrogen Compound Metabolic Process Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Positive Regulation Of Gene Expression Establishment Of Organelle Localization Apoptotic Process Transcription, DNA-templated Programmed Cell Death Regulation Of Signaling Microtubule-based Process Steroid Hormone Mediated Signaling Pathway Developmental Process Cell Death Death Establishment Of Localization In Cell RNA Biosynthetic Process Metaphase Plate Congression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Positive Regulation Of Organelle Organization Transcription From RNA Polymerase II Promoter Response To Organic Substance G2/M Transition Of Mitotic Cell Cycle Organelle Localization Heterocycle Metabolic Process Establishment Of Protein Localization Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process
Tagcloud ?		10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin	advance amelanotic behaviour colonization doi ezh2 heterogeneity heterogeneous intravital kif2c melanoma motile motility moving notch november oca2 onc online ordinated overlapping pigment polycomb publication repressive singly srf streams suppressing
Tagcloud (Difference) ?		10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin	advance amelanotic behaviour colonization doi ezh2 heterogeneity heterogeneous intravital kif2c melanoma motile motility moving notch november oca2 onc online ordinated overlapping pigment polycomb publication repressive singly srf streams suppressing
Tagcloud (Intersection) ?