SVIL and MRTFB

Number of citations of the paper that reports this interaction (PubMedID 20309963)
81

Data Source:
BioGRID (two hybrid)

		SVIL	MRTFB
Description		supervillin	myocardin related transcription factor B
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane Midbody Cleavage Furrow Microtubule Minus-end Cell Projection Costamere Anchoring Junction	Nucleus Cytoplasm Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	Actin Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding	Transcription Coactivator Activity Protein Binding Cadherin Binding
	Biological Process	Cytoskeleton Organization Skeletal Muscle Tissue Development Actin Polymerization Or Depolymerization Positive Regulation Of Cytokinesis Actin Filament Severing Barbed-end Actin Filament Capping Muscle Structure Development	Muscle Organ Development Cell Differentiation Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Transcription By RNA Polymerase II Smooth Muscle Cell Differentiation Regulation Of Modification Of Postsynaptic Structure Positive Regulation Of MiRNA Transcription
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155) Plateletcrit ( 32888494)
Interacting Genes		36 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A STARD9 TGFB1I1 TMEM132D TNFAIP1 TRIP6 UXT YWHAG	8 interacting genes: KDM3A KPNA4 MRTFA NCOA3 SMAD1 SMAD7 SRF SVIL
Entrez ID		6840	57496
HPRD ID		04992	17577
Ensembl ID		ENSG00000197321	ENSG00000186260
Uniprot IDs		A0A6I8PIX7 O95425 Q569J5	I3L2S3 Q9ULH7
PDB IDs		2K6M 2K6N
Enriched GO Terms of Interacting Partners?		Organelle Organization Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Estrogen Response Element Binding Cytoskeleton Identical Protein Binding Nucleus Regulation Of Organelle Organization Nuclear Receptor Activity Positive Regulation Of MiRNA Transcription Positive Regulation Of MiRNA Metabolic Process Cytoplasm Regulation Of Apoptotic Process Steroid Binding Regulation Of Programmed Cell Death Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Pore Localization Chromatin Binding Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Receptor-mediated Signaling Pathway Apoptotic Process Regulation Of Cellular Component Organization Positive Regulation Of Macromolecule Metabolic Process Cytosol Cell Death Programmed Cell Death Nitric-oxide Synthase Regulator Activity Positive Regulation Of Macromolecule Biosynthetic Process Spindle Regulation Of Gene Expression Regulation Of Chromosome Organization Nuclear Matrix Cytoskeleton Organization Prostate Gland Growth Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Intracellular Protein Localization Chromosome Segregation Microtubule Binding Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Microtubule-based Process Microtubule Motor Activity Hormone-mediated Signaling Pathway Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Response To Estrogen Chromatin Organization Nuclear Lamina Microtubule Cytoskeleton Organization Negative Regulation Of Apoptotic Process	Male Germ Cell Nucleus Heteromeric SMAD Protein Complex Regulation Of MiRNA Transcription Positive Regulation Of MiRNA Metabolic Process Primary MiRNA Binding Positive Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process I-SMAD Binding SMAD Protein Signal Transduction Muscle Tissue Development Smooth Muscle Cell Differentiation Positive Regulation Of Cartilage Development Regulation Of B Cell Antigen Processing And Presentation Regulation Of Cell Differentiation Positive Regulation Of Multicellular Organismal Process Immune Complex Clearance By Monocytes And Macrophages Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of Type I Hypersensitivity Negative Regulation Of Antibody-dependent Cellular Cytotoxicity Ureteric Bud Development Epithelium Development Mesonephric Epithelium Development Chromatin Mesonephric Tubule Development Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Serum Response Element Binding Podosome Formaldehyde Biosynthetic Process Artery Morphogenesis Negative Regulation Of Cell Population Proliferation Cellular Developmental Process Negative Regulation Of Adaptive Immune Response Low-affinity IgG Receptor Activity Tissue Development Homomeric SMAD Protein Complex Regulation Of Cartilage Development Kidney Epithelium Development Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Chondrocyte Development Bronchus Cartilage Development Lung Smooth Muscle Development Regulation Of Stem Cell Population Maintenance PDZ Domain Binding Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Immune Complex Clearance By Monocytes And Macrophages Negative Regulation Of Cytotoxic T Cell Degranulation Regulation Of Multicellular Organismal Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?