GPT and CDC7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GPT	CDC7
Gene Name		glutamic-pyruvate transaminase (alanine aminotransferase)	cell division cycle 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	L-alanine:2-oxoglutarate Aminotransferase Activity Pyridoxal Phosphate Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding
	Biological Process	Cellular Amino Acid Biosynthetic Process Cellular Nitrogen Compound Metabolic Process L-alanine Catabolic Process Small Molecule Metabolic Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Double-strand Break Repair Via Break-induced Replication DNA Replication DNA Replication Initiation Phagocytosis Positive Regulation Of Cell Proliferation Regulation Of Cell Shape Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Peptidyl-serine Phosphorylation Cell Cycle Phase Transition Cell Division
Pathways		Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives	G1/S Transition G2/M Checkpoints Activation of ATR in response to replication stress Activation of the pre-replicative complex DNA Replication Pre-Initiation M/G1 Transition Cell Cycle Checkpoints Activation of the pre-replicative complex Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs		Pyridoxal Phosphate L-Glutamic Acid L-Alanine Phenelzine
Diseases
GWAS			Optic disc parameters ( 20548946 21307088)
Protein-Protein Interactions		2 interactors: CAPN1 CDC7	24 interactors: APP CDK2 CDK4 CDK9 CDKN1A CDKN2A CHAF1A CLSPN DBF4 DBF4B DIAPH1 GPT GRHPR MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC5 ORC6 TOB1
Entrez ID		2875	8317
HPRD ID		00689	10345
Ensembl ID		ENSG00000167701	ENSG00000097046
Uniprot IDs		P24298	B2R6V2 J3KQS2 O00311
PDB IDs			4F99 4F9A 4F9B 4F9C
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Break-induced Replication Positive Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Nuclear Cell Cycle DNA Replication Receptor Catabolic Process Positive Regulation Of Cell Proliferation Positive Regulation Of DNA-dependent DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle DNA Replication Initiation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Cell Proliferation Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of DNA Replication Receptor Metabolic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Extracellular Matrix Disassembly DNA-dependent DNA Replication Positive Regulation Of Mitotic Cell Cycle Peptidyl-serine Phosphorylation Regulation Of DNA Replication Positive Regulation Of DNA Metabolic Process Double-strand Break Repair G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Shape	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication Mitotic Cell Cycle Process Mitotic Cell Cycle DNA Replication Initiation DNA-dependent DNA Replication Cell Cycle Cell Cycle Process DNA Metabolic Process DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation DNA Duplex Unwinding DNA Geometric Change DNA Unwinding Involved In DNA Replication DNA Conformation Change Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Cell Cycle Process Chromosome Organization Macromolecule Biosynthetic Process Regulation Of Cell Cycle Arrest Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Biosynthetic Process Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Phosphorylation Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Arrest Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Kinase Activity Cellular Response To Stress Organelle Organization Regulation Of Kinase Activity
Tagcloud ?		acth adrenocortical amphotericin anergy calcitriol candidiasis capsules clouding constellation electrocautery exclude gluconate got hypoparathyroidism manifest merieux microgram mucocutaneous multitest noninfectious occipital parathormone phpt pointing poliosis polyglandular transaminases truncal vitiligo	af ana antinuclear assignment beads blots cdc10 cdc2 cdc4 cdc5 cdc9 dilutions foundation immunodiffusion intensities jo monospecific originally purposes reagents reference rnp ro semiquantitative sera ss u1 weaker
Tagcloud (Difference) ?		acth adrenocortical amphotericin anergy calcitriol candidiasis capsules clouding constellation electrocautery exclude gluconate got hypoparathyroidism manifest merieux microgram mucocutaneous multitest noninfectious occipital parathormone phpt pointing poliosis polyglandular transaminases truncal vitiligo	af ana antinuclear assignment beads blots cdc10 cdc2 cdc4 cdc5 cdc9 dilutions foundation immunodiffusion intensities jo monospecific originally purposes reagents reference rnp ro semiquantitative sera ss u1 weaker
Tagcloud (Intersection) ?