GPT

Name	glutamic--pyruvic transaminase
Structure	No pdb structure
Interactors	2 interactors: CAPN1 CDC7
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	L-alanine:2-oxoglutarate Aminotransferase Activity Transaminase Activity Transferase Activity Pyridoxal Phosphate Binding
	Biological Process	L-alanine Catabolic Process
Pathways	Pyruvate metabolism Alanine metabolism
Drugs	Pyridoxal phosphate Glutamic acid Alanine Phenelzine
GWAS	Age at first birth ( 27798627 ) Alanine aminotransferase levels ( 30718733 33339817 ) Educational attainment ( 25201988 ) GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273 )
Entrez ID	2875
HPRD ID	00689
Ensembl ID	ENSG00000167701
Uniprot IDs	P24298
PDB IDs	Not available
GO Terms Enriched among Interactors ?	NMDA Selective Glutamate Receptor Signaling Pathway Calcium-dependent Cysteine-type Endopeptidase Activity Calpain Complex Self Proteolysis Mammary Gland Involution Double-strand Break Repair Via Break-induced Replication Positive Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of DNA-templated DNA Replication Receptor Catabolic Process Positive Regulation Of Cell Population Proliferation Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Ligand-gated Ion Channel Signaling Pathway Positive Regulation Of DNA Replication Receptor Metabolic Process Glutamate Receptor Signaling Pathway Cornified Envelope Tissue Remodeling Regulation Of Cell Population Proliferation Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle