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NUP62 and XPO6
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
HPRD
(two hybrid)
NUP62
XPO6
Gene Name
nucleoporin 62kDa
exportin 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Spindle Pole
Nuclear Envelope
Nuclear Pore
Cytoplasm
Ribonucleoprotein Complex
Nucleocytoplasmic Shuttling Complex
Nuclear Membrane
Intracellular Membrane-bounded Organelle
Pore Complex
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Plasma Membrane
Molecular Function
Chromatin Binding
Nucleocytoplasmic Transporter Activity
Protein Binding
Structural Constituent Of Nuclear Pore
Receptor Signaling Complex Scaffold Activity
SH2 Domain Binding
Ubiquitin Binding
Thyroid Hormone Receptor Binding
PTB Domain Binding
Protein Binding
Ran GTPase Binding
Protein Transporter Activity
Biological Process
Mitotic Cell Cycle
Carbohydrate Metabolic Process
Transcription, DNA-templated
Nucleocytoplasmic Transport
Mitotic Nuclear Envelope Disassembly
Cell Surface Receptor Signaling Pathway
Cell Aging
Cell Death
Negative Regulation Of Cell Proliferation
Hexose Transport
Pathogenesis
Hormone-mediated Signaling Pathway
Regulation Of Signal Transduction
Gene Expression
Regulation Of Glucose Transport
Protein Transport
Glucose Transport
Viral Process
Viral Life Cycle
Viral Transcription
Cytokine-mediated Signaling Pathway
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of MAP Kinase Activity
Small Molecule Metabolic Process
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Ras Protein Signal Transduction
MRNA Transport
Transmembrane Transport
Protein Export From Nucleus
Pathways
Mitotic Prophase
HIV Infection
Nuclear import of Rev protein
Regulatory RNA pathways
Rev-mediated nuclear export of HIV RNA
Nuclear Envelope Breakdown
SLC-mediated transmembrane transport
M Phase
Influenza Life Cycle
HIV Life Cycle
Influenza Viral RNA Transcription and Replication
Rev-mediated nuclear export of HIV RNA
Myoclonic epilepsy of Lafora
Glycogen storage diseases
Transcriptional regulation by small RNAs
Vpr-mediated nuclear import of PICs
ISG15 antiviral mechanism
Interferon Signaling
Host Interactions of HIV factors
Nuclear Pore Complex (NPC) Disassembly
Regulation of Glucokinase by Glucokinase Regulatory Protein
Cytokine Signaling in Immune system
Interactions of Vpr with host cellular proteins
Interactions of Rev with host cellular proteins
Influenza Infection
Hexose transport
Cell Cycle, Mitotic
Late Phase of HIV Life Cycle
Antiviral mechanism by IFN-stimulated genes
Viral Messenger RNA Synthesis
Metabolism of carbohydrates
Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions
65 interactors:
ABI2
ADAM15
AGR3
ATXN7
BFSP1
BLOC1S6
C1orf216
CCDC121
CCDC146
CCDC150
CCDC153
CCDC53
CCHCR1
CENPU
CEP57L1
CLIC1
CRCT1
DDX3X
DGCR6
DTNB
FABP3
GOPC
GORASP2
GTF2E2
HAUS1
HSF2
IFT20
IK
IKBIP
IPO5
ISCU
KANSL1
KIFC3
KLHL32
KPNA1
KPNA2
KPNB1
KRT20
LMO2
MUC1
MYO15B
NFX1
NUP153
NUP54
NUP98
NUPL1
NUTF2
NXF1
NXF2
OGT
OIP5
PBX2
PHF21A
PIN1
PTMA
RANBP2
SMARCE1
SNAPC5
SP1
SSC5D
THAP1
TRAF3
TXLNA
XPO1
XPO6
5 interactors:
ACTB
DIAPH1
NUP62
PFN1
VASP
Entrez ID
23636
23214
HPRD ID
05782
10525
Ensembl ID
ENSG00000213024
ENSG00000169180
Uniprot IDs
P37198
B3KW08
D3DWF9
Q96QU8
PDB IDs
2H4D
Enriched GO Terms of Interacting Partners
?
Nucleocytoplasmic Transport
Nuclear Transport
Viral Process
Cytoplasmic Transport
MRNA Transport
RNA Transport
RNA Localization
Intracellular Transport
Nuclear Import
Nucleus Organization
Viral Life Cycle
NLS-bearing Protein Import Into Nucleus
Mitotic Nuclear Envelope Disassembly
Nuclear Envelope Disassembly
Establishment Of Localization In Cell
Protein Transport
Protein Localization To Nucleus
Cytokine-mediated Signaling Pathway
Establishment Of Protein Localization
Nuclear Export
Cellular Localization
Protein Import Into Nucleus
Protein Export From Nucleus
Intracellular Transport Of Virus
Nuclear Envelope Organization
Glucose Transport
Protein Localization
Cellular Response To Cytokine Stimulus
Organelle Organization
Protein Import
Mitotic Cell Cycle
Hexose Transport
Cellular Protein Localization
Viral Transcription
Regulation Of Glucose Transport
Response To Cytokine
RNA Biosynthetic Process
Intracellular Protein Transport
Cell Cycle
Carbohydrate Transport
Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis
Cellular Response To Organic Substance
Protein Localization To Organelle
Gene Expression
Response To Organic Substance
Protein Targeting
Nuclear Pore Complex Assembly
Pathogenesis
Establishment Of Protein Localization To Organelle
Ribosomal Protein Import Into Nucleus
Organelle Organization
Actin Polymerization Or Depolymerization
Actin Cytoskeleton Organization
Actin Filament-based Process
Neural Tube Closure
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Protein Polymerization
Neural Tube Formation
Embryonic Epithelial Tube Formation
Epithelial Tube Formation
Neuron Projection Development
Nervous System Development
Tube Formation
Positive Regulation Of Protein Complex Assembly
Morphogenesis Of Embryonic Epithelium
Regulation Of Actin Filament Polymerization
Neuron Development
Platelet Activation
Neural Tube Development
Developmental Process
Cell Junction Assembly
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Positive Regulation Of Cytoskeleton Organization
Cytoskeleton Organization
Neuron Differentiation
Cell Projection Organization
Positive Regulation Of Ruffle Assembly
Immune Response-activating Cell Surface Receptor Signaling Pathway
Protein Localization To Microtubule
Actin Filament Organization
Positive Regulation Of Cellular Component Biogenesis
Cellular Response To Stimulus
Regulation Of Cellular Component Size
Positive Regulation Of Cell Migration
Cellular Response To Histamine
Regulation Of Protein Complex Assembly
Positive Regulation Of Cell Motility
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Locomotion
Regulation Of Actin Cytoskeleton Organization
Negative Regulation Of Stress Fiber Assembly
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Response To Histamine
Epithelial Tube Morphogenesis
Generation Of Neurons
Axon Guidance
Negative Regulation Of Actin Filament Bundle Assembly
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Tagcloud
?
barr
bblf2
bblf4
betaherpesviruses
bglf4
bslf1
cotransfected
dilation
ebv
egress
epstein
fg
gammaherpesviruses
gateways
import
importin
lytic
mpm
nls
nlss
nucleocapsids
nucleocytoplasmic
nucleoporins
nup153
nups
pore
reorganization
replicating
vca
Tagcloud (Difference)
?
barr
bblf2
bblf4
betaherpesviruses
bglf4
bslf1
cotransfected
dilation
ebv
egress
epstein
fg
gammaherpesviruses
gateways
import
importin
lytic
mpm
nls
nlss
nucleocapsids
nucleocytoplasmic
nucleoporins
nup153
nups
pore
reorganization
replicating
vca
Tagcloud (Intersection)
?