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NUP62 and SMARCE1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
NUP62
SMARCE1
Description
nucleoporin 62
SWI/SNF related BAF chromatin remodeling complex subunit E1
Image
GO Annotations
Cellular Component
Spindle Pole
Nucleus
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Cytoplasm
Centrosome
Cytoskeleton
Nuclear Membrane
Nuclear Pore Central Transport Channel
Mitotic Spindle
Flemming Body
Ribonucleoprotein Complex
Nuclear Chromosome
Kinetochore
Chromatin
Nucleus
Nucleoplasm
Nuclear Matrix
SWI/SNF Complex
RSC-type Complex
Protein-containing Complex
Brahma Complex
NpBAF Complex
NBAF Complex
BBAF Complex
Molecular Function
Chromatin Binding
Protein Binding
Phospholipid Binding
Structural Constituent Of Nuclear Pore
Signaling Receptor Complex Adaptor Activity
Hsp70 Protein Binding
SH2 Domain Binding
Ubiquitin Binding
PTB Domain Binding
Hsp90 Protein Binding
DNA Binding
Chromatin Binding
Transcription Coactivator Activity
RNA Binding
Protein Binding
N-acetyltransferase Activity
Nuclear Receptor Binding
Nucleosomal DNA Binding
Biological Process
RNA Export From Nucleus
Protein Import Into Nucleus
Nucleocytoplasmic Transport
Mitotic Metaphase Chromosome Alignment
Centrosome Cycle
Mitotic Centrosome Separation
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Regulation Of Signal Transduction
Protein Transport
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of DNA-templated Transcription
Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Centriole Replication
MRNA Transport
Regulation Of Mitotic Spindle Organization
Cellular Senescence
Centriole Assembly
Positive Regulation Of Mitotic Cytokinetic Process
Positive Regulation Of Protein Localization To Centrosome
Chromatin Organization
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Neurogenesis
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Myoblast Differentiation
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Regulation Of G0 To G1 Transition
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Double-strand Break Repair
Regulation Of Nucleotide-excision Repair
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
IPs transport between nucleus and cytosol
IP3 and IP4 transport between cytosol and nucleus
IP6 and IP7 transport between cytosol and nucleus
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Formation of the canonical BAF (cBAF) complex
Formation of the polybromo-BAF (pBAF) complex
Formation of the embryonic stem cell BAF (esBAF) complex
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
Allergic disease (asthma, hay fever and/or eczema) (age of onset) (
32603359
)
Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) (
32603359
)
Allergic disease (asthma, hay fever or eczema) (
29083406
29785011
)
Allergic rhinitis (
31361310
)
Asthma (
30929738
31619474
31959851
)
Asthma (childhood onset) (
30929738
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Eczema (
31361310
)
Triglyceride levels in HIV infection (
33109212
)
Interacting Genes
88 interacting genes:
ABI2
ADAM15
AGR3
ARFIP2
ATF7IP2
ATXN7
BFSP1
BLOC1S6
C14orf119
C1orf216
CAVIN3
CCDC121
CCDC146
CCDC150
CCHCR1
CENPU
CEP57L1
CLIC1
CRCT1
DDX3X
DGCR6
DPPA3
DRC12
DTNB
DYNLT1
FABP3
GOPC
GORASP2
GTF2E2
HAUS1
HGS
HSF2
HSF4
IDH1
IFT20
IFT25
IK
IKBIP
IPO5
ISCU
KANSL1
KIFC3
KLHL32
KPNA1
KPNA2
KPNB1
KRT1
KRT20
KRT3
KRT6A
KRT6B
KRT75
LMO2
LNX1
MUC1
MXD3
MYO15B
NUP153
NUP54
NUP58
NUP98
NUTF2
NXF1
NXF2
OGT
OIP5
OTUD6A
PBX2
PELI2
PIN1
PTMA
RANBP2
SMARCA2
SMARCE1
SNAPC5
SP1
SSC5D
SUOX
THAP1
TLE4
TRAF3
TRIML2
TXLNA
TXN
USHBP1
WASHC3
XPO1
XPO6
94 interacting genes:
AMOTL2
AR
ARID2
BAZ1B
BRAP
BRMS1
CCDC136
CCDC172
CCDC183
CCHCR1
CDR2
CEBPA
CEP170P1
CEP63
CEP70
CYSRT1
DISC1
EPS8
ERG
ESR1
ESR2
EXOC4
EXOC7
FAM217B
FSD2
GATA1
GOLGA2
GOLGA6L9
GRIPAP1
HUNK
IFT74
IFT88
ING5
ITCH
JAKMIP2
KIFC3
KLF1
KRT14
KRT15
KRT16
KRT19
KRT27
KRT31
KRT34
KRT35
KRT37
KRT39
KRT40
KRTAP1-1
KRTAP10-8
KRTAP10-9
KRTAP6-3
MDM2
MED4
MEOX2
MIPOL1
MRFAP1L1
MTUS2
NBPF22P
NCOA1
NCOA2
NCOA3
NOTCH2NLA
NR0B2
NR3C1
NUP62
OGT
OIP5
PGR
PSMC6
RALBP1
RARB
RCOR1
RELB
RINT1
RSPH1
SIN3A
SIN3B
SMAD1
SMARCA4
SPAG5
SRC
STX11
SYCE1
TEX12
TFE3
TFIP11
TIAM1
TNIK
TRIM54
TRIP10
TXLNA
USHBP1
VPS52
Entrez ID
23636
6605
HPRD ID
05782
04382
Ensembl ID
ENSG00000213024
ENSG00000073584
Uniprot IDs
P37198
Q969G3
PDB IDs
5IJN
5IJO
7PER
7R5J
7R5K
6LTH
6LTJ
7CYU
7VDV
7Y8R
Enriched GO Terms of Interacting Partners
?
Nuclear Transport
Nucleocytoplasmic Transport
Nuclear Localization Sequence Binding
Nuclear Pore
NLS-bearing Protein Import Into Nucleus
RNA Transport
Protein Import Into Nucleus
Import Into Nucleus
Nuclear Export
MRNA Transport
Intracellular Transport
Nuclear Import Signal Receptor Activity
Protein Localization To Nucleus
Protein Transport
Establishment Of Protein Localization
Structural Constituent Of Nuclear Pore
Intermediate Filament Organization
Nuclear Membrane
Nucleobase-containing Compound Transport
Nuclear Inclusion Body
Protein Binding
Intermediate Filament Cytoskeleton Organization
Structural Constituent Of Skin Epidermis
Intermediate Filament-based Process
Intracellular Protein Transport
Cellular Localization
Protein Localization To Organelle
Establishment Of Localization In Cell
Establishment Of Protein Localization To Organelle
Supramolecular Fiber Organization
Nuclear Envelope
Intracellular Protein Localization
Intracellular Transport Of Virus
Keratin Filament
Host Cell
NLS-dependent Protein Nuclear Import Complex
Cytoskeleton Organization
Small GTPase Binding
Intermediate Filament
Protein Export From Nucleus
Keratinization
Nuclear Pore Nuclear Basket
Regulation Of Nucleocytoplasmic Transport
Nuclear Pore Organization
Identical Protein Binding
RNA Export From Nucleus
Nucleus Organization
Organelle Organization
Ribosomal Protein Import Into Nucleus
Viral Penetration Into Host Nucleus
Keratin Filament
Intermediate Filament
Structural Constituent Of Skin Epidermis
Intermediate Filament Organization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Nuclear Receptor-mediated Signaling Pathway
Morphogenesis Of An Epithelium
Cytoskeleton
Tissue Morphogenesis
Estrogen Response Element Binding
Chromatin
Structural Molecule Activity
Protein Binding
Intracellular Receptor Signaling Pathway
Cytoskeleton Organization
Organelle Organization
Hormone-mediated Signaling Pathway
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Chromatin Binding
Steroid Binding
Nuclear Receptor Activity
Supramolecular Fiber Organization
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Epithelial Cell Differentiation
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Intracellular Signal Transduction
Anatomical Structure Morphogenesis
Cellular Developmental Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Steroid Receptor Activity
Sin3-type Complex
Estrogen Receptor Signaling Pathway
Positive Regulation Of Stem Cell Population Maintenance
Cytosol
Positive Regulation Of RNA Metabolic Process
Epidermis Development
Cell Differentiation
DNA-binding Transcription Factor Activity
Protein-containing Complex
Cellular Response To Hormone Stimulus
Negative Regulation Of Transcription By RNA Polymerase II
Nucleoplasm
Developmental Process
Transcription Repressor Complex
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
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Tagcloud (Intersection)
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