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NUP62 and IPO5
Number of citations of the paper that reports this interaction (PubMedID
9114010
)
34
Data Source:
HPRD
(in vitro, in vivo)
NUP62
IPO5
Description
nucleoporin 62
importin 5
Image
GO Annotations
Cellular Component
Spindle Pole
Nucleus
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Cytoplasm
Centrosome
Cytoskeleton
Nuclear Membrane
Nuclear Pore Central Transport Channel
Mitotic Spindle
Flemming Body
Ribonucleoprotein Complex
Nucleus
Nuclear Pore
Nucleoplasm
Nucleolus
Cytoplasm
Golgi Apparatus
Cytosol
Membrane
Nuclear Membrane
Molecular Function
Chromatin Binding
Protein Binding
Phospholipid Binding
Structural Constituent Of Nuclear Pore
Signaling Receptor Complex Adaptor Activity
Hsp70 Protein Binding
SH2 Domain Binding
Ubiquitin Binding
PTB Domain Binding
Hsp90 Protein Binding
RNA Binding
GTPase Inhibitor Activity
Protein Binding
Nuclear Localization Sequence Binding
Small GTPase Binding
Nuclear Import Signal Receptor Activity
Biological Process
RNA Export From Nucleus
Protein Import Into Nucleus
Nucleocytoplasmic Transport
Mitotic Metaphase Chromosome Alignment
Centrosome Cycle
Mitotic Centrosome Separation
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Regulation Of Signal Transduction
Protein Transport
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of DNA-templated Transcription
Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Centriole Replication
MRNA Transport
Regulation Of Mitotic Spindle Organization
Cellular Senescence
Centriole Assembly
Positive Regulation Of Mitotic Cytokinetic Process
Positive Regulation Of Protein Localization To Centrosome
Cytoplasmic Pattern Recognition Receptor Signaling Pathway
Protein Import Into Nucleus
NLS-bearing Protein Import Into Nucleus
Ribosomal Protein Import Into Nucleus
Intracellular Protein Transport
Protein Transport
Positive Regulation Of Protein Import Into Nucleus
Negative Regulation Of Cell Cycle
Cellular Response To Amino Acid Stimulus
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
IPs transport between nucleus and cytosol
IP3 and IP4 transport between cytosol and nucleus
IP6 and IP7 transport between cytosol and nucleus
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
vRNP Assembly
Drugs
Diseases
GWAS
Peripheral artery disease (
26488411
)
Smooth-surface caries (
24556642
)
Interacting Genes
88 interacting genes:
ABI2
ADAM15
AGR3
ARFIP2
ATF7IP2
ATXN7
BFSP1
BLOC1S6
C14orf119
C1orf216
CAVIN3
CCDC121
CCDC146
CCDC150
CCHCR1
CENPU
CEP57L1
CLIC1
CRCT1
DDX3X
DGCR6
DPPA3
DRC12
DTNB
DYNLT1
FABP3
GOPC
GORASP2
GTF2E2
HAUS1
HGS
HSF2
HSF4
IDH1
IFT20
IFT25
IK
IKBIP
IPO5
ISCU
KANSL1
KIFC3
KLHL32
KPNA1
KPNA2
KPNB1
KRT1
KRT20
KRT3
KRT6A
KRT6B
KRT75
LMO2
LNX1
MUC1
MXD3
MYO15B
NUP153
NUP54
NUP58
NUP98
NUTF2
NXF1
NXF2
OGT
OIP5
OTUD6A
PBX2
PELI2
PIN1
PTMA
RANBP2
SMARCA2
SMARCE1
SNAPC5
SP1
SSC5D
SUOX
THAP1
TLE4
TRAF3
TRIML2
TXLNA
TXN
USHBP1
WASHC3
XPO1
XPO6
31 interacting genes:
ACD
CAB39
CDC42
DPPA3
DTNBP1
GPRASP3
H1-0
NOSIP
NRIP1
NUP153
NUP214
NUP62
NUP98
OGT
PRRC2B
PTEN
RAG2
RAN
RANBP2
RNF10
RPL13
RPL23
RPL23A
RPL5
RPL7
RPS7
SRP19
SUMO2
TERF1
TINF2
WASL
Entrez ID
23636
3843
HPRD ID
05782
03597
Ensembl ID
ENSG00000213024
ENSG00000065150
Uniprot IDs
P37198
B3KWG6
O00410
Q9BVS9
PDB IDs
5IJN
5IJO
7PER
7R5J
7R5K
6XTE
6XU2
9IM6
Enriched GO Terms of Interacting Partners
?
Nuclear Transport
Nucleocytoplasmic Transport
Nuclear Localization Sequence Binding
Nuclear Pore
NLS-bearing Protein Import Into Nucleus
RNA Transport
Protein Import Into Nucleus
Import Into Nucleus
Nuclear Export
MRNA Transport
Intracellular Transport
Nuclear Import Signal Receptor Activity
Protein Localization To Nucleus
Protein Transport
Establishment Of Protein Localization
Structural Constituent Of Nuclear Pore
Intermediate Filament Organization
Nuclear Membrane
Nucleobase-containing Compound Transport
Nuclear Inclusion Body
Protein Binding
Intermediate Filament Cytoskeleton Organization
Structural Constituent Of Skin Epidermis
Intermediate Filament-based Process
Intracellular Protein Transport
Cellular Localization
Protein Localization To Organelle
Establishment Of Localization In Cell
Establishment Of Protein Localization To Organelle
Supramolecular Fiber Organization
Nuclear Envelope
Intracellular Protein Localization
Intracellular Transport Of Virus
Keratin Filament
Host Cell
NLS-dependent Protein Nuclear Import Complex
Cytoskeleton Organization
Small GTPase Binding
Intermediate Filament
Protein Export From Nucleus
Keratinization
Nuclear Pore Nuclear Basket
Regulation Of Nucleocytoplasmic Transport
Nuclear Pore Organization
Identical Protein Binding
RNA Export From Nucleus
Nucleus Organization
Organelle Organization
Ribosomal Protein Import Into Nucleus
Viral Penetration Into Host Nucleus
Cytosolic Ribosome
Import Into Nucleus
Protein Import Into Nucleus
Cytoplasmic Translation
Establishment Of Protein Localization To Organelle
Nuclear Pore
Nucleus
Ribonucleoprotein Complex
Protein Localization To Nucleus
Cytosolic Large Ribosomal Subunit
Structural Constituent Of Nuclear Pore
RNA Binding
Protein Localization To Organelle
Nuclear Export
Shelterin Complex
Nuclear Transport
Nucleocytoplasmic Transport
RNA Transport
Structural Constituent Of Ribosome
RNA Export From Nucleus
Nucleolus
Negative Regulation Of Ubiquitin Protein Ligase Activity
Nuclear Telomere Cap Complex
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Ubiquitin-protein Transferase Activity
Nucleoplasm
Ribosome
Nuclear Inclusion Body
Ubiquitin Ligase Inhibitor Activity
Telomere Capping
Nuclear Pore Nuclear Basket
Nucleobase-containing Compound Transport
Nuclear Envelope
Translation
MRNA Transport
Intracellular Transport
Intracellular Protein Transport
Dendritic Spine Morphogenesis
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Cellular Localization
Negative Regulation Of Telomere Maintenance Via Telomerase
Nuclear Localization Sequence Binding
Negative Regulation Of Protein Ubiquitination
Negative Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Organelle Localization
Nuclear Pore Cytoplasmic Filaments
Negative Regulation Of RNA Export From Nucleus
Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
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Tagcloud (Intersection)
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