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IL7R and RRAGA
Number of citations of the paper that reports this interaction (PMID
23151878
)
3
Data Source:
BioGRID
(unspecified method)
IL7R
RRAGA
Gene Name
interleukin 7 receptor
Ras-related GTP binding A
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
Nucleus
Cytoplasm
Lysosome
Lysosomal Membrane
Golgi Apparatus
EGO Complex
Intracellular Membrane-bounded Organelle
Gtr1-Gtr2 GTPase Complex
Molecular Function
Antigen Binding
Interleukin-7 Receptor Activity
Protein Binding
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Phosphoprotein Binding
Biological Process
Regulation Of DNA Recombination
Cell Morphogenesis
Negative Regulation Of T Cell Mediated Cytotoxicity
Immunoglobulin Production
Immune Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Size
Positive Regulation Of Gene Expression
Cell Growth
T Cell Differentiation
Positive Regulation Of T Cell Differentiation In Thymus
Interleukin-7-mediated Signaling Pathway
B Cell Proliferation
Lymph Node Development
Homeostasis Of Number Of Cells
Apoptotic Process
Cell Death
Cellular Response To Starvation
Regulation Of Autophagy
Modulation By Virus Of Host Morphology Or Physiology
Positive Regulation Of TOR Signaling
Cellular Protein Localization
Positive Regulation Of Cytolysis
Cellular Response To Amino Acid Stimulus
Pathways
Signaling by Interleukins
Interleukin-7 signaling
Cytokine Signaling in Immune system
Drugs
Diseases
GWAS
Multiple sclerosis (
21244703
19525953
21833088
)
Primary biliary cirrhosis (
23000144
21399635
)
Type 1 diabetes (
17554260
)
Ulcerative colitis (
21297633
)
Protein-Protein Interactions
104 interactors:
ALYREF
CIRBP
CPSF1
CRLF2
DDX21
DDX39B
DDX3X
DDX5
DHX36
DHX9
EIF2AK2
ELAVL1
EMG1
FAU
FUS
FYN
G3BP1
GNB2L1
H1FX
HIST1H1C
HIST1H1E
HIST2H2BE
HNRNPA0
HNRNPA3
HNRNPAB
HNRNPC
HNRNPD
HNRNPDL
HNRNPH3
HNRNPL
HNRNPR
HNRNPU
HNRNPUL1
HNRNPUL2
IL2RG
IL7
ILF2
ILF3
JAK1
JAK3
KIT
LYN
MAP4
NCL
NONO
PABPC1
PABPC4
PABPN1
PIK3R1
PTBP1
PTK2B
PTMA
PURA
PURB
QKI
RAD21
RBM3
RBMX
RPL15
RPL18
RPL22
RPL29
RPL30
RPL31
RPL6
RPL7
RPL8
RPS20
RPS3
RPSA
RRAGA
RSL1D1
SAFB
SF1
SF3A1
SF3B1
SNRNP70
SNRPA
SNRPB
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNRPF
SNRPG
SRP14
SRP9
SRSF3
SRSF9
SSB
STAT3
STAT5A
STAT5B
SYNCRIP
TOE1
TOP1
TSLP
U2AF1
U2AF2
YBX1
YBX3
YWHAE
YWHAG
ZNF787
9 interactors:
CPSF1
CPSF4
CSTF3
IL7R
NOL8
PAPOLA
RPTOR
RRAGC
RRAGD
Entrez ID
3575
10670
HPRD ID
00893
10205
Ensembl ID
ENSG00000168685
ENSG00000155876
Uniprot IDs
D6RGV2
D9N160
P16871
Q7L523
PDB IDs
3DI2
3DI3
3UP1
Enriched GO Terms of Interacting Partners
?
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Processing
RNA Splicing
MRNA Processing
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Viral Process
RNA Biosynthetic Process
SRP-dependent Cotranslational Protein Targeting To Membrane
Termination Of RNA Polymerase II Transcription
Cotranslational Protein Targeting To Membrane
Protein Targeting To ER
Establishment Of Protein Localization To Endoplasmic Reticulum
Cellular Macromolecule Biosynthetic Process
Regulation Of MRNA Stability
Regulation Of RNA Stability
Macromolecule Biosynthetic Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Protein Localization To Endoplasmic Reticulum
Viral Life Cycle
Cytoplasmic Transport
Posttranscriptional Regulation Of Gene Expression
MRNA Stabilization
RNA 3'-end Processing
MRNA 3'-end Processing
RNA Catabolic Process
Viral Transcription
Cellular Metabolic Process
Protein Targeting To Membrane
DNA-templated Transcription, Termination
Protein Targeting
Nuclear-transcribed MRNA Catabolic Process
Establishment Of Protein Localization To Organelle
MRNA Catabolic Process
Ribonucleoprotein Complex Assembly
Regulation Of Translation
Ribonucleoprotein Complex Biogenesis
Biosynthetic Process
Protein Localization To Organelle
Translational Termination
Establishment Of Protein Localization To Membrane
Intracellular Transport
Translational Elongation
Positive Regulation Of TOR Signaling
RNA Polyadenylation
Termination Of RNA Polymerase II Transcription
RNA Processing
Regulation Of TOR Signaling
Cellular Response To Amino Acid Stimulus
DNA-templated Transcription, Termination
MRNA 3'-end Processing
RNA Splicing
RNA 3'-end Processing
Response To Amino Acid
MRNA Processing
Cell Growth
MRNA Cleavage
MRNA Metabolic Process
Cellular Response To Acid Chemical
Cellular Response To Nutrient Levels
MRNA Polyadenylation
Cellular Response To Extracellular Stimulus
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Metabolic Process
Response To Nutrient Levels
Response To Extracellular Stimulus
Cellular Response To Organonitrogen Compound
Growth
Regulation Of Autophagy
Interleukin-7-mediated Signaling Pathway
Modification By Virus Of Host MRNA Processing
Regulation Of Cell Size
Cellular Response To Starvation
Negative Regulation Of T Cell Mediated Cytotoxicity
Response To Starvation
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Response To Organonitrogen Compound
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Response To Organic Substance
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase III Promoter
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Negative Regulation Of T Cell Mediated Immunity
Modulation By Virus Of Host Process
Lymph Node Development
Cellular Macromolecule Biosynthetic Process
Nucleic Acid Phosphodiester Bond Hydrolysis
Positive Regulation Of T Cell Differentiation In Thymus
Macromolecule Biosynthetic Process
Tagcloud
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
sqstm1
warranted
wnt1
Tagcloud (Difference)
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
sqstm1
warranted
wnt1
Tagcloud (Intersection)
?