IL7R and PURA

Number of citations of the paper that reports this interaction (PMID 23151878)
3

Data Source:
BioGRID (unspecified method)

		IL7R	PURA
Gene Name		interleukin 7 receptor	purine-rich element binding protein A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane	Nuclear Chromosome, Telomeric Region Nucleus DNA Replication Factor A Complex Cytoplasm Dendrite Neuronal Cell Body
	Molecular Function	Antigen Binding Interleukin-7 Receptor Activity Protein Binding	Translation Repressor Activity, Nucleic Acid Binding Double-stranded Telomeric DNA Binding Single-stranded DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Purine-rich Negative Regulatory Element Binding Poly(A) RNA Binding SMAD Binding
	Biological Process	Regulation Of DNA Recombination Cell Morphogenesis Negative Regulation Of T Cell Mediated Cytotoxicity Immunoglobulin Production Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Cell Size Positive Regulation Of Gene Expression Cell Growth T Cell Differentiation Positive Regulation Of T Cell Differentiation In Thymus Interleukin-7-mediated Signaling Pathway B Cell Proliferation Lymph Node Development Homeostasis Of Number Of Cells	DNA Unwinding Involved In DNA Replication DNA Replication Initiation Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Nervous System Development Positive Regulation Of Cell Proliferation Negative Regulation Of Translation Negative Regulation Of Transcription, DNA-templated
Pathways		Signaling by Interleukins Interleukin-7 signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS		Multiple sclerosis ( 21244703 19525953 21833088) Primary biliary cirrhosis ( 23000144 21399635) Type 1 diabetes ( 17554260) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		104 interactors: ALYREF CIRBP CPSF1 CRLF2 DDX21 DDX39B DDX3X DDX5 DHX36 DHX9 EIF2AK2 ELAVL1 EMG1 FAU FUS FYN G3BP1 GNB2L1 H1FX HIST1H1C HIST1H1E HIST2H2BE HNRNPA0 HNRNPA3 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPH3 HNRNPL HNRNPR HNRNPU HNRNPUL1 HNRNPUL2 IL2RG IL7 ILF2 ILF3 JAK1 JAK3 KIT LYN MAP4 NCL NONO PABPC1 PABPC4 PABPN1 PIK3R1 PTBP1 PTK2B PTMA PURA PURB QKI RAD21 RBM3 RBMX RPL15 RPL18 RPL22 RPL29 RPL30 RPL31 RPL6 RPL7 RPL8 RPS20 RPS3 RPSA RRAGA RSL1D1 SAFB SF1 SF3A1 SF3B1 SNRNP70 SNRPA SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SRP14 SRP9 SRSF3 SRSF9 SSB STAT3 STAT5A STAT5B SYNCRIP TOE1 TOP1 TSLP U2AF1 U2AF2 YBX1 YBX3 YWHAE YWHAG ZNF787	10 interactors: ADAP1 CCNT1 CDK5 E2F1 IL7R PURB RAF1 RB1 SP1 YBX1
Entrez ID		3575	5813
HPRD ID		00893	02721
Ensembl ID		ENSG00000168685
Uniprot IDs		D6RGV2 D9N160 P16871	Q00577
PDB IDs		3DI2 3DI3 3UP1
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing RNA Splicing MRNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Viral Process RNA Biosynthetic Process SRP-dependent Cotranslational Protein Targeting To Membrane Termination Of RNA Polymerase II Transcription Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Macromolecule Biosynthetic Process Regulation Of MRNA Stability Regulation Of RNA Stability Macromolecule Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Protein Localization To Endoplasmic Reticulum Viral Life Cycle Cytoplasmic Transport Posttranscriptional Regulation Of Gene Expression MRNA Stabilization RNA 3'-end Processing MRNA 3'-end Processing RNA Catabolic Process Viral Transcription Cellular Metabolic Process Protein Targeting To Membrane DNA-templated Transcription, Termination Protein Targeting Nuclear-transcribed MRNA Catabolic Process Establishment Of Protein Localization To Organelle MRNA Catabolic Process Ribonucleoprotein Complex Assembly Regulation Of Translation Ribonucleoprotein Complex Biogenesis Biosynthetic Process Protein Localization To Organelle Translational Termination Establishment Of Protein Localization To Membrane Intracellular Transport Translational Elongation	Positive Regulation Of Metabolic Process Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Enucleate Erythrocyte Differentiation Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process MRNA Stabilization Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Homeostasis Of Number Of Cells Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Viral Transcription Regulation Of Protein Kinase Activity Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Regulation Of Kinase Activity Regulation Of MRNA Stability Regulation Of RNA Stability Neuron Apoptotic Process Signaling Cell Communication Neuron Death Regulation Of Signal Transduction Regulation Of Viral Transcription Regulation Of Cell Cycle Positive Regulation Of Viral Process Death-inducing Signaling Complex Assembly Sequestering Of Nodal From Receptor Via Nodal Binding Regulation Of Transcription, DNA-templated Apoptotic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Organ Development Positive Regulation Of Organelle Organization Cellular Response To Organic Substance Programmed Cell Death
Tagcloud ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	abbott accu aliquoted aviva bayer chek contour electrochemistry freestyle hct hematocrit heparinized lifescan lite lots mard meter meters mylife mystar onetouch performa roche sanofi strip verio xt ypsomed ysi
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	abbott accu aliquoted aviva bayer chek contour electrochemistry freestyle hct hematocrit heparinized lifescan lite lots mard meter meters mylife mystar onetouch performa roche sanofi strip verio xt ypsomed ysi
Tagcloud (Intersection) ?