ZNF417 and IKZF1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZNF417	IKZF1
Gene Name		zinc finger protein 417	IKAROS family zinc finger 1 (Ikaros)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Pericentric Heterochromatin Cytoplasm Protein Complex
	Molecular Function	DNA Binding Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Natural Killer Cell Differentiation Transcription, DNA-templated Cell Cycle Mesoderm Development Chromatin Modification B Cell Differentiation T Cell Differentiation Forebrain Development Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lymph Node Development Thymus Development Peyer's Patch Development Positive Regulation Of NK T Cell Differentiation Retina Development In Camera-type Eye
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 23512250 19684603 19684604) Crohn's disease ( 21102463) Hippocampal atrophy ( 19668339) IgG glycosylation ( 23382691) Inflammatory bowel disease ( 23128233) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517) Systemic lupus erythematosus ( 23273568 19838193)
Protein-Protein Interactions		66 interactors: ADAMTSL4 BEGAIN BEND5 CARD9 CCDC136 CCDC57 CCDC85B CEP44 CEP70 CEP72 CSRNP1 EFS FHL2 FHL3 FSD2 GOLGA2 HMBOX1 IKZF1 KLC3 KRT15 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KXD1 LURAP1 LZTS2 MDFI MEOX2 MID2 MTUS2 NDEL1 NINL NOTCH2NL PHC2 PLSCR1 PNMA2 REL RPGRIP1 RUNDC3A SPRY2 SSX2IP STX11 TCF4 TFIP11 TMCC2 TNS2 TRAF1 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSGA10 ZBTB1 ZBTB10 ZBTB43 ZBTB8A ZNF587	75 interactors: AEN ALKBH3 ANKRD11 AP1M1 AP2M1 ARMC7 BYSL C19orf66 C1orf109 C1orf174 C8orf33 CBX8 CDK2AP2 CEP57L1 CHD3 CKS1B CSNK1G1 CTBP1 CTBP2 DCX DDX6 DYRK2 FAM161A FAM214B FAM50B FAM74A4 FGF12 FRMD6 GLRX3 GMCL1P1 GTF2B HDAC1 HDAC2 IKZF2 IKZF3 IKZF4 IKZF5 ISCU KIF9 LMO3 LSM4 MAD2L2 MCRS1 MORF4L1 MORF4L2 MTA1 NEK6 NOC4L NUDT21 PIN1 PNKP PRKAB2 PSMA1 PSMA4 RAD51D RBBP8 RWDD2B SAP18 SCNM1 SDCBP SH2D4A SIN3A SIN3B SMARCA4 SNRPF SNW1 SPATC1L SYT17 TBP TDG UBE2I WTAP ZMAT2 ZNF417 ZNF581
Entrez ID		147687	10320
HPRD ID		18341	04318
Ensembl ID			ENSG00000185811
Uniprot IDs		Q8TAU3	Q13422
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression RNA Metabolic Process Negative Regulation Of Viral Release From Host Cell Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Viral Process Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Microtubule-based Process Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Viral Transcription Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Viral Release From Host Cell Positive Regulation Of Intracellular Signal Transduction Developmental Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cell Cycle Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cytoskeleton Organization Organ Development G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Positive Regulation Of NF-kappaB Transcription Factor Activity Mitotic Cell Cycle Process Microtubule-based Transport Positive Regulation Of Neutrophil Differentiation Spliceosomal Complex Disassembly Positive Regulation Of Pro-T Cell Differentiation Cellular Localization Cytoskeleton-dependent Intracellular Transport Face Morphogenesis Organelle Organization Positive Regulation Of Gene Expression Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway	RNA Metabolic Process Gene Expression Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Organelle Organization Chromosome Organization Chromatin Modification Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Negative Regulation Of Gene Expression Histone Deacetylation Protein Deacetylation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA Repair Regulation Of Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Metabolic Process Regulation Of Cell Cycle Phase Transition RNA Splicing
Tagcloud ?			agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Difference) ?			agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Intersection) ?