ZNF417 and KIF9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF417	KIF9
Description		zinc finger protein 417	kinesin family member 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Podosome Cytoplasm Cytoskeleton Kinesin Complex Microtubule Cilium Motile Cilium Vesicle Sperm Flagellum Cell Projection
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity Identical Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription	Microtubule-based Movement Extracellular Matrix Disassembly Regulation Of Podosome Assembly Regulation Of Flagellated Sperm Motility Organelle Disassembly
Pathways		Generic Transcription Pathway	COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		Depression in smokers ( 30219690)	Adiponectin levels ( 31178129) Huntington's disease progression ( 28642124) Platelet count ( 32888494) Platelet distribution width ( 32888494) Refractive error ( 32231278) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		170 interacting genes: - ADAMTSL4 AXIN2 BEGAIN BEND5 BEX3 BICD2 C4orf17 CARD9 CBY2 CCDC125 CCDC136 CCDC57 CCDC85B CCNDBP1 CDR2 CDR2L CEP44 CEP70 CEP72 CEP85L CHRDL2 COG6 CSRNP1 CYSRT1 DEF8 DVL3 EFS EZHIP FAM221A FHL2 FHL3 FHL5 FRS3 FSD2 FXR1 GOLGA2 GOLGA6L9 GPRASP3 HMBOX1 HOMEZ HOOK2 HOXA1 HSF2BP IGFBP6 IHO1 IKZF1 INKA1 JADE2 JRK KAT5 KATNBL1 KCTD7 KIF9 KIFC3 KLC3 KRT15 KRT31 KRT35 KRT38 KRT39 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-9 KXD1 LHX3 LIMS1 LMO1 LURAP1 LZTS1 LZTS2 MAGEA8 MAST2 MCC MCCD1 MDFI MEIS3 MEOX2 MID2 MIIP MRFAP1L1 MTUS2 MYF5 MYLIP NAB2 NBPF19 NDEL1 NDUFB7 NINL NKAPL NKX3-1 NOTCH2NLA OIP5 PHC2 PICK1 PIH1D2 PLSCR1 PNMA2 PRICKLE4 PRPF31 RCN3 REL RHOQ RNF187 RORB RPGRIP1 RUNDC3A SH2B2 SMARCD1 SMYD5 SPRED1 SPRED2 SPRY1 SPRY2 SSX2IP STX11 SUV39H1 TADA2A TCF4 TEKT4 TFIP11 TLE5 TMCC2 TNS2 TRAF1 TRAF2 TRIB3 TRIM23 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSC1 TSGA10 TXNDC11 U2AF1 USHBP1 VPS16 VPS52 VWC2 ZBTB1 ZBTB10 ZBTB43 ZBTB8A ZBTB9 ZNF165 ZNF19 ZNF20 ZNF547 ZNF572 ZNF587 ZNF69 ZNF71 ZNF768 ZNF774 ZNF837 ZNF85 ZRANB1	63 interacting genes: ACBD4 ALAS1 AMOTL2 ATP5IF1 BLZF1 CARD9 CCDC125 CYTIP DISC1 EFHC2 EMD FXR1 GOLGA6A HMBOX1 HOOK2 HSF2BP IHO1 IKZF1 IKZF3 INKA1 IQCB1 JAKMIP2 KANK2 KCTD9 KRT75 KRTAP10-3 KRTAP10-6 KRTAP10-9 LZTS1 LZTS2 MAD1L1 MID1 MID2 MIPOL1 NAB2 OIP5 OOEP PIBF1 PNMA5 PPP1R13B PRICKLE1 PRMT6 RBM48 RBM5 ROPN1 SHISA6 SLAIN1 SSX2IP STEEP1 TFIP11 TRIM27 TRIM37 TRIM54 VIM VPS52 ZBTB8A ZC2HC1C ZCCHC7 ZNF417 ZNF436 ZNF566 ZNF572 ZRANB1
Entrez ID		147687	64147
HPRD ID		18341	07444
Ensembl ID		ENSG00000173480	ENSG00000088727
Uniprot IDs		M0R230 Q8TAU3	A8K932 Q6PJI1 Q9HAQ2
PDB IDs			3NWN
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Protein Binding Identical Protein Binding Zinc Ion Binding Negative Regulation Of Lens Fiber Cell Differentiation Regulation Of Lens Fiber Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Structural Constituent Of Skin Epidermis Cytoskeleton Protein Serine/threonine Kinase Inhibitor Activity Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Microtubule Binding Cytoskeleton Organization Microtubule-based Process Regulation Of Nucleobase-containing Compound Metabolic Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Microtubule DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Organelle Organization Hair Cycle Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Stem Cell Factor Receptor Binding	Identical Protein Binding Protein Binding Organelle Organization Microtubule Protein Localization To Cytoskeleton Microtubule-based Process Cytoskeleton Organization Microtubule Cytoskeleton Organization Intermediate Filament Negative Regulation Of Nucleobase-containing Compound Metabolic Process Keratin Filament Zinc Ion Binding Wnt Signaling Pathway
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