S100A13 and S100A14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		S100A13	S100A14
Description		S100 calcium binding protein A13	S100 calcium binding protein A14
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm	Extracellular Space Cytoplasm Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Copper Ion Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Lipid Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding	Calcium Ion Binding Protein Binding Chemokine Receptor Binding Calcium-dependent Protein Binding
	Biological Process	Positive Regulation Of Cytokine Production Protein Transport Positive Regulation Of Interleukin-1 Alpha Production Positive Regulation Of Canonical NF-kappaB Signal Transduction Mast Cell Degranulation	Apoptotic Process Response To Lipopolysaccharide Toll-like Receptor 4 Signaling Pathway Defense Response To Bacterium Calcium Ion Homeostasis Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Monocyte Chemotaxis
Pathways
Drugs		Olopatadine Amlexanox Calcium chloride Calcium Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Plateletcrit ( 32888494)
Interacting Genes		10 interacting genes: FBXO7 FGF1 IGBP1 IL1A IRF9 PHYHIP PLEKHF2 S100A14 SYT1 TNF	11 interacting genes: AKT1 AURKA CASP8 FGFR2 MAGEA6 S100A13 S100A16 SMAD4 STK11 UCHL5 WEE2-AS1
Entrez ID		6284	57402
HPRD ID		03586	10467
Ensembl ID		ENSG00000189171	ENSG00000189334
Uniprot IDs		Q99584	Q9HCY8
PDB IDs		1YUR 1YUS 1YUT 1YUU 2EGD 2H2K 2K8M 2KI4 2KI6 2KOT 2L5X 2LE9	2M0R
Enriched GO Terms of Interacting Partners?		Positive Regulation Of MAP Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Steroid Biosynthetic Process Regulation Of MAPK Cascade Branch Elongation Involved In Ureteric Bud Branching Cellular Response To Heat Positive Regulation Of Steroid Metabolic Process Immune System Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Mitotic Nuclear Division Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Synchronous Neurotransmitter Secretion Negative Regulation Of Bile Acid Secretion Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Response To Gram-negative Bacterium Negative Regulation Of Branching Involved In Lung Morphogenesis Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of MAP Kinase Activity Response To Lipopolysaccharide Regulation Of Vasculature Development Regulation Of Angiogenesis Regulation Of Anatomical Structure Morphogenesis Regulation Of Steroid Biosynthetic Process Response To Heat Regulation Of Morphogenesis Of An Epithelium Regulation Of Animal Organ Morphogenesis Response To Molecule Of Bacterial Origin Calcium-dependent Protein Binding Syntaxin-3 Binding Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Amine Transport Chronic Inflammatory Response To Antigenic Stimulus Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Fractalkine Production Positive Regulation Of Blood Microparticle Formation Response To Gold Nanoparticle Positive Regulation Of Vitamin D Biosynthetic Process Positive Regulation Of Cell Division Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Lipid Biosynthetic Process Regulation Of Steroid Metabolic Process Fever Generation	Protein Autophosphorylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Reproductive Process Positive Regulation Of Cell Communication Protein Phosphorylation Peptidyl-threonine Phosphorylation Positive Regulation Of Signaling Regulation Of Proteolysis Anoikis Regulation Of Protein Catabolic Process Positive Regulation Of Developmental Process Negative Regulation Of Catabolic Process Protein Homodimerization Activity Phosphorylation Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction By P53 Class Mediator Developmental Growth Fibroblast Growth Factor Binding Developmental Growth Involved In Morphogenesis Regulation Of Cell Development Regulation Of Signal Transduction Regulation Of Multicellular Organismal Development Execution Phase Of Apoptosis Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cell Differentiation Protein Serine/threonine/tyrosine Kinase Activity Apoptotic Process Developmental Process Involved In Reproduction Regulation Of Protein Metabolic Process Outflow Tract Septum Morphogenesis Regulation Of Cell Differentiation Regulation Of Ubiquitin-dependent Protein Catabolic Process Programmed Cell Death Cell Death Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Midbrain Development Protein Kinase Activity Regulation Of Developmental Process Positive Regulation Of Proteolysis Carbohydrate Homeostasis Positive Regulation Of Metabolic Process Glucose Homeostasis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Multicellular Organismal Process Regulation Of Cell Communication Regulation Of Signaling Anterior/posterior Axis Specification Regulation Of Cell Cycle Peptidyl-serine Phosphorylation
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