S100A13 and IRF9

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		S100A13	IRF9
Description		S100 calcium binding protein A13	interferon regulatory factor 9
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol ISGF3 Complex
	Molecular Function	Copper Ion Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Lipid Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Cytokine Production Protein Transport Positive Regulation Of Interleukin-1 Alpha Production Positive Regulation Of Canonical NF-kappaB Signal Transduction Mast Cell Degranulation	Immune System Process Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Cell Surface Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus
Pathways			Interferon gamma signaling Interferon alpha/beta signaling
Drugs		Olopatadine Amlexanox Calcium chloride Calcium Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Plateletcrit ( 32888494)
Interacting Genes		10 interacting genes: FBXO7 FGF1 IGBP1 IL1A IRF9 PHYHIP PLEKHF2 S100A14 SYT1 TNF	20 interacting genes: ARID3B DACH2 DMRTC2 HOXC9 IFNA1 ILF3 IRF1 IRF2BP1 MYO1F NFKB1 NR2E3 POU2F1 RELA S100A13 STAT1 STAT2 TLX2 TLX3 TOP1 VENTX
Entrez ID		6284	10379
HPRD ID		03586	00960
Ensembl ID		ENSG00000189171	ENSG00000213928
Uniprot IDs		Q99584	A0A8V8TMJ8 A0A8V8TP83 H0YNP4 Q00978
PDB IDs		1YUR 1YUS 1YUT 1YUU 2EGD 2H2K 2K8M 2KI4 2KI6 2KOT 2L5X 2LE9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of MAP Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Steroid Biosynthetic Process Regulation Of MAPK Cascade Branch Elongation Involved In Ureteric Bud Branching Cellular Response To Heat Positive Regulation Of Steroid Metabolic Process Immune System Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Mitotic Nuclear Division Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Synchronous Neurotransmitter Secretion Negative Regulation Of Bile Acid Secretion Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Response To Gram-negative Bacterium Negative Regulation Of Branching Involved In Lung Morphogenesis Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of MAP Kinase Activity Response To Lipopolysaccharide Regulation Of Vasculature Development Regulation Of Angiogenesis Regulation Of Anatomical Structure Morphogenesis Regulation Of Steroid Biosynthetic Process Response To Heat Regulation Of Morphogenesis Of An Epithelium Regulation Of Animal Organ Morphogenesis Response To Molecule Of Bacterial Origin Calcium-dependent Protein Binding Syntaxin-3 Binding Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Amine Transport Chronic Inflammatory Response To Antigenic Stimulus Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Fractalkine Production Positive Regulation Of Blood Microparticle Formation Response To Gold Nanoparticle Positive Regulation Of Vitamin D Biosynthetic Process Positive Regulation Of Cell Division Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Lipid Biosynthetic Process Regulation Of Steroid Metabolic Process Fever Generation	DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Response To Virus DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleus Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Defense Response To Virus Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process NF-kappaB P50/p65 Complex Interferon-mediated Signaling Pathway RNA Polymerase II Core Promoter Sequence-specific DNA Binding Positive Regulation Of RNA Metabolic Process Nucleoplasm ISGF3 Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cytokine-mediated Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of RNA Metabolic Process Response To Peptide Hormone Transcription Coactivator Binding Type I Interferon-mediated Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Nicotine Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Peptide Hormone Stimulus Regulation Of Interleukin-12 Production Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Response To Mechanical Stimulus Actinin Binding DNA-templated Transcription Type II Interferon-mediated Signaling Pathway
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