DDX39B and HIPK2

Number of citations of the paper that reports this interaction (PMID 14667819)
24

Data Source:
HPRD (two hybrid)

		DDX39B	HIPK2
Gene Name		DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	homeodomain interacting protein kinase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex Nucleus Nucleoplasm Spliceosomal Complex U4 SnRNP U6 SnRNP Cytoplasm Nuclear Speck	Nucleus Cytoplasm Nuclear Body PML Body RNA Polymerase II Transcription Factor Complex
	Molecular Function	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity U6 SnRNA Binding U4 SnRNA Binding ATP-dependent Protein Binding Poly(A) RNA Binding	RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Coactivator Activity Transcription Corepressor Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding SMAD Binding Virion Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome MRNA Export From Nucleus RNA Splicing RNA Secondary Structure Unwinding Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of DNA Damage Checkpoint	Negative Regulation Of Transcription From RNA Polymerase II Promoter Eye Development Positive Regulation Of Protein Phosphorylation Transcription, DNA-templated Protein Phosphorylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Transforming Growth Factor Beta Receptor Signaling Pathway Smoothened Signaling Pathway Adult Walking Behavior Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Retina Layer Formation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Modulation By Virus Of Host Morphology Or Physiology Neuron Differentiation Erythrocyte Differentiation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway PML Body Organization Positive Regulation Of Protein Binding Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of DNA Binding Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Angiogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of JNK Cascade Embryonic Camera-type Eye Morphogenesis Voluntary Musculoskeletal Movement Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Cycle Embryonic Retina Morphogenesis In Camera-type Eye Lens Induction In Camera-type Eye SMAD Protein Signal Transduction Iris Morphogenesis Cellular Response To Hypoxia Intrinsic Apoptotic Signaling Pathway
Pathways			Generic Transcription Pathway YAP1- and WWTR1 (TAZ)-stimulated gene expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ALYREF BARD1 DDX39A DNM2 EXOSC9 FANCA HIPK2 HNRNPLL IL7R NCBP2 PIAS2 RBM39 RPS15A SARNP SREK1 STRN4 TDG THOC3 THOC5 THOC6 THOC7 TUBB3 YWHAG ZHX1	48 interactors: AATF BTRC CHMP4B CREBBP CUL1 CXCL1 DAXX DDX39A DDX39B EP300 FBXW7 HIST2H2BE HMGA1 KAT2B MAP3K7 MBP MDM2 MECP2 MKNK1 MYB MYBL1 NKX2-1 NKX2-5 NKX3-1 NLK PAX6 PML PTCH1 RANBP9 RUNX1 SENP1 SIAH1 SIAH2 SKI SMAD1 SMAD2 SMAD3 SP100 SUMO1 SUMO2 TP53 TP53INP1 TP63 TP73 TRADD UBE2I WSB1 ZBTB4
Entrez ID		7919	28996
HPRD ID		00805	06039
Ensembl ID		ENSG00000198563	ENSG00000064393
Uniprot IDs		Q13838	Q9H2X6
PDB IDs		1T5I 1T6N 1XTI 1XTJ 1XTK
Enriched GO Terms of Interacting Partners?		MRNA Export From Nucleus RNA Export From Nucleus Viral MRNA Export From Host Cell Nucleus MRNA Metabolic Process Nuclear Export MRNA Transport RNA Transport RNA Localization MRNA Processing RNA Splicing Intracellular Transport Of Virus RNA Processing Nucleocytoplasmic Transport Nuclear Transport RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cytoplasmic Transport Viral Life Cycle Viral Process Intracellular Transport Establishment Of Localization In Cell Cellular Metabolic Process Cellular Localization Regulation Of RNA Export From Nucleus Positive Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription, Elongation Nuclear-transcribed MRNA Catabolic Process Regulation Of RNA Metabolic Process MRNA Catabolic Process Termination Of RNA Polymerase II Transcription RNA Catabolic Process Regulation Of Intracellular Transport Aromatic Compound Catabolic Process Regulation Of Nucleocytoplasmic Transport Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Transport Regulation Of DNA-templated Transcription, Elongation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Metabolic Process SnRNA Export From Nucleus	Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Response To Organic Substance Apoptotic Process Transcription, DNA-templated Cellular Response To Organic Substance Tube Development Regulation Of Signaling Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of Cell Death Regulation Of Protein Metabolic Process Response To Stimulus Cell Death Death Regulation Of Signal Transduction Negative Regulation Of Cell Proliferation Regulation Of Apoptotic Process Regulation Of Cell Proliferation Cell Cycle RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Transcription From RNA Polymerase II Promoter Cell Cycle Process Regulation Of Cell Cycle Cell Communication Gene Expression Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway
Tagcloud ?		22c 348c acc agc agt amazon asymptomatic bat1 brazilian categorized cc complicated ga gg ggt haplotypes helicase il6 malaria mild ncoi nlaiii plasmodium polymorphisms postulation restriction snps uninfected vivax	adding complexity decisions determines e3 fail fate favoring feedback finger homeodomain inactivated interferes ligase loop preferentially proline siah2 stimulates switch termination ubiquitin ubiquitination uncovers waf1 xaf1 xiap zinc znf313
Tagcloud (Difference) ?		22c 348c acc agc agt amazon asymptomatic bat1 brazilian categorized cc complicated ga gg ggt haplotypes helicase il6 malaria mild ncoi nlaiii plasmodium polymorphisms postulation restriction snps uninfected vivax	adding complexity decisions determines e3 fail fate favoring feedback finger homeodomain inactivated interferes ligase loop preferentially proline siah2 stimulates switch termination ubiquitin ubiquitination uncovers waf1 xaf1 xiap zinc znf313
Tagcloud (Intersection) ?