DDX39B and SARNP

Number of citations of the paper that reports this interaction (PubMedID 15338056)
41

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		DDX39B	SARNP
Description		DExD-box helicase 39B	SAP domain containing ribonucleoprotein
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GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nucleoplasm Spliceosomal Complex U4 SnRNP U6 SnRNP Cytoplasm Nuclear Speck	Transcription Export Complex Nucleus Nucleoplasm Nuclear Speck Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On RNA Hydrolase Activity ATP Hydrolysis Activity U6 SnRNA Binding U4 SnRNA Binding Identical Protein Binding ATP-dependent Protein Binding	DNA Binding Chromatin Binding RNA Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA Transport	Negative Regulation Of Transcription By RNA Polymerase II MRNA Export From Nucleus Regulation Of Translation Poly(A)+ MRNA Export From Nucleus MRNA Transport
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination RHOBTB2 GTPase cycle	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Artenimol
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) High light scatter reticulocyte count ( 32888494) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Mean platelet volume ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 27863252) Mosquito bite size ( 28199695) Myositis ( 26291516) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 28067908)	Kawasaki disease ( 33772158) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		31 interacting genes: ALYREF BARD1 DDX39A DNM2 EXOSC9 FANCA HIPK2 HNRNPLL IL7R LUZP4 NCBP2 OGT PIAS2 PKM RBM39 RNF4 RPS15A SARNP SDCBP SNRPA SREBF1 SREK1 SRPK2 STRN4 TDG THOC3 THOC6 TUBB3 UBE2I YWHAG ZHX1	9 interacting genes: CEBPA CSNK2B DAPK1 DDX39A DDX39B ESR1 EXOSC8 VHL YTHDF1
Entrez ID		7919	84324
HPRD ID		00805	16716
Ensembl ID		ENSG00000198563	ENSG00000205323
Uniprot IDs		A0A024RCM3 Q13838	P82979
PDB IDs		1T5I 1T6N 1XTI 1XTJ 1XTK 7APK 7ZNK 7ZNL 8ENK	2DO1
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleoplasm MRNA Metabolic Process Nucleus Nuclear Speck Nuclear Export MRNA Export From Nucleus MRNA Transport MRNA Processing Transcription Export Complex RNA Export From Nucleus RNA Transport RNA Splicing Nucleic Acid Metabolic Process Nucleobase-containing Compound Transport Macromolecule Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process Nuclear Transport Nucleocytoplasmic Transport RNA Metabolic Process PML Body Nucleic Acid Binding Regulation Of Nucleobase-containing Compound Metabolic Process Protein K6-linked Ubiquitination Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II THO Complex Part Of Transcription Export Complex U1 SnRNP Binding MRNA Binding Regulation Of MRNA Processing Negative Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of MRNA 3'-end Processing Regulation Of Macromolecule Metabolic Process Response To Insulin Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process	Identical Protein Binding Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Notch Signaling Pathway Chromatin Binding Nucleoplasm CHOP-C/EBP Complex RNA Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Response To Vitamin B2 White Fat Cell Proliferation Positive Regulation Of RNA Metabolic Process Memory C/EBP Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of NMDA Receptor Activity DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Nuclear Estrogen Receptor Activity TFIIB-class Transcription Factor Binding Prostate Epithelial Cord Elongation Positive Regulation Of Nitric-oxide Synthase Activity Mammary Gland Branching Involved In Pregnancy Antral Ovarian Follicle Growth Helicase Activity RNA Export From Nucleus MRNA Export From Nucleus MRNA Transport Nuclear Export MRNA Binding RNA Helicase Activity Negative Regulation Of RNA Export From Nucleus U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Release From Viral Latency Regulation Of Branching Involved In Prostate Gland Morphogenesis Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Catabolic Process
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