DDX39B and THOC6

Number of citations of the paper that reports this interaction (PMID 17190602)
119

Data Source:
BioGRID (affinity chromatography technology, biochemical, pull down)

		DDX39B	THOC6
Gene Name		DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	THO complex 6 homolog (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex Nucleus Nucleoplasm Spliceosomal Complex U4 SnRNP U6 SnRNP Cytoplasm Nuclear Speck	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity U6 SnRNA Binding U4 SnRNA Binding ATP-dependent Protein Binding Poly(A) RNA Binding	RNA Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome MRNA Export From Nucleus RNA Splicing RNA Secondary Structure Unwinding Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of DNA Damage Checkpoint	MRNA Processing MRNA Export From Nucleus Apoptotic Process Central Nervous System Development RNA Splicing Negative Regulation Of Apoptotic Process Viral MRNA Export From Host Cell Nucleus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ALYREF BARD1 DDX39A DNM2 EXOSC9 FANCA HIPK2 HNRNPLL IL7R NCBP2 PIAS2 RBM39 RPS15A SARNP SREK1 STRN4 TDG THOC3 THOC5 THOC6 THOC7 TUBB3 YWHAG ZHX1	2 interactors: ALYREF DDX39B
Entrez ID		7919	79228
HPRD ID		00805	14504
Ensembl ID		ENSG00000198563	ENSG00000131652
Uniprot IDs		Q13838	Q86W42
PDB IDs		1T5I 1T6N 1XTI 1XTJ 1XTK
Enriched GO Terms of Interacting Partners?		MRNA Export From Nucleus RNA Export From Nucleus Viral MRNA Export From Host Cell Nucleus MRNA Metabolic Process Nuclear Export MRNA Transport RNA Transport RNA Localization MRNA Processing RNA Splicing Intracellular Transport Of Virus RNA Processing Nucleocytoplasmic Transport Nuclear Transport RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cytoplasmic Transport Viral Life Cycle Viral Process Intracellular Transport Establishment Of Localization In Cell Cellular Metabolic Process Cellular Localization Regulation Of RNA Export From Nucleus Positive Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription, Elongation Nuclear-transcribed MRNA Catabolic Process Regulation Of RNA Metabolic Process MRNA Catabolic Process Termination Of RNA Polymerase II Transcription RNA Catabolic Process Regulation Of Intracellular Transport Aromatic Compound Catabolic Process Regulation Of Nucleocytoplasmic Transport Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Transport Regulation Of DNA-templated Transcription, Elongation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Metabolic Process SnRNA Export From Nucleus	Viral MRNA Export From Host Cell Nucleus Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation MRNA Export From Nucleus RNA Export From Nucleus Nuclear Export MRNA Transport RNA Transport RNA Localization Viral Life Cycle MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleocytoplasmic Transport Nuclear Transport RNA Splicing RNA Secondary Structure Unwinding Negative Regulation Of DNA Damage Checkpoint MRNA Processing MRNA Metabolic Process Viral Process RNA Processing Cytoplasmic Transport Regulation Of DNA Damage Checkpoint Replication Fork Processing Regulation Of Cell Cycle Checkpoint Positive Regulation Of Transcription, DNA-templated Termination Of RNA Polymerase II Transcription Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Transport Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Spliceosomal Complex Assembly Regulation Of DNA Recombination DNA-templated Transcription, Termination MRNA 3'-end Processing Establishment Of Localization In Cell RNA 3'-end Processing DNA-dependent DNA Replication Cellular Localization Regulation Of Response To DNA Damage Stimulus Osteoblast Differentiation Positive Regulation Of Cellular Metabolic Process Ribonucleoprotein Complex Assembly RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression DNA Replication Ossification Ribonucleoprotein Complex Biogenesis
Tagcloud ?		22c 348c acc agc agt amazon asymptomatic bat1 brazilian categorized cc complicated ga gg ggt haplotypes helicase il6 malaria mild ncoi nlaiii plasmodium polymorphisms postulation restriction snps uninfected vivax
Tagcloud (Difference) ?		22c 348c acc agc agt amazon asymptomatic bat1 brazilian categorized cc complicated ga gg ggt haplotypes helicase il6 malaria mild ncoi nlaiii plasmodium polymorphisms postulation restriction snps uninfected vivax
Tagcloud (Intersection) ?