WDR77 and PPIL1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		WDR77	PPIL1
Gene Name		WD repeat domain 77	peptidylprolyl isomerase (cyclophilin)-like 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome	Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Gene Expression NcRNA Metabolic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding
Pathways		Chromatin modifying enzymes snRNP Assembly Chromatin organization Metabolism of non-coding RNA RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: AQR BAG2 COPRS CTDP1 GPKOW HIST2H2AB HNRNPM LSM3 NKX3-1 PCBP2 PPIL1 PPP1R8 PQBP1 PRMT5 QKI RBM5 SAP30BP SF1 SF3A1 SF3B4 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZNF207	15 interactors: CPSF6 GADD45G HNRNPA1 HNRNPUL1 PPP1R8 PRR22 RBM42 RIMBP3 SF3B3 SNW1 SRPK1 SRPK2 TCF4 THOC5 WDR77
Entrez ID		79084	51645
HPRD ID		14387	03194
Ensembl ID		ENSG00000116455	ENSG00000137168
Uniprot IDs		B4DP38 Q9BQA1	Q9Y3C6
PDB IDs		4GQB	1XWN 2K7N 2X7K
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing MRNA Metabolic Process Gene Expression RNA Metabolic Process Ribonucleoprotein Complex Assembly Spliceosomal SnRNP Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Transcription, DNA-templated Histone MRNA Metabolic Process RNA Biosynthetic Process Cellular Metabolic Process Cellular Component Assembly NcRNA Metabolic Process Termination Of RNA Polymerase II Transcription DNA-templated Transcription, Termination MRNA 3'-end Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA 3'-end Processing MRNA 3'-splice Site Recognition Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Histone Methylation Regulation Of RNA Metabolic Process MRNA Splice Site Selection Biosynthetic Process Histone H4-R3 Methylation Protein Methylation Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Alternative MRNA Splicing, Via Spliceosome Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of RNA Splicing Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription	MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Viral Process Positive Regulation Of Viral Genome Replication Regulation Of Viral Process Regulation Of RNA Metabolic Process Viral Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Viral Genome Replication Nucleocytoplasmic Transport Nuclear Transport Nuclear Speck Organization Regulation Of Viral Genome Replication RNA Export From Nucleus Negative Regulation Of Viral Process Cell Differentiation Regulation Of Metabolic Process Positive Regulation Of Vitamin D Receptor Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Regulation Of Cell Cycle Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Nuclear Export MRNA Transport Nucleus Organization Nuclear Import Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint Maintenance Of DNA Repeat Elements Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Cellular Component Assembly Cellular Metabolic Process RNA Transport RNA Localization Regulation Of Vitamin D Receptor Signaling Pathway
Tagcloud ?		androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 ncoa4 p44 pca promotion spliced suppressive switch switches tblr1 versions
Tagcloud (Difference) ?		androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 ncoa4 p44 pca promotion spliced suppressive switch switches tblr1 versions
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