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WDR77 and HNRNPM
Number of citations of the paper that reports this interaction (PubMedID
22365833
)
0
Data Source:
BioGRID
(two hybrid, two hybrid)
WDR77
HNRNPM
Description
WD repeat domain 77
heterogeneous nuclear ribonucleoprotein M
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Cul4B-RING E3 Ubiquitin Ligase Complex
Methylosome
Transferase Complex
Nucleus
Nucleoplasm
Spliceosomal Complex
Nucleolus
Membrane
Nuclear Matrix
Paraspeckles
Synapse
Extracellular Exosome
Catalytic Step 2 Spliceosome
Ribonucleoprotein Complex
Molecular Function
Transcription Coactivator Activity
Protein Binding
Methyl-CpG Binding
Ubiquitin-like Ligase-substrate Adaptor Activity
Nucleic Acid Binding
RNA Binding
MRNA Binding
Protein Binding
Protein Domain Specific Binding
Biological Process
Protein Polyubiquitination
Spliceosomal SnRNP Assembly
Regulation Of Transcription By RNA Polymerase II
Ubiquitin-dependent Protein Catabolic Process
Oocyte Axis Specification
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of MRNA Splicing, Via Spliceosome
Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development
Epithelial Cell Proliferation Involved In Prostate Gland Development
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Pathways
snRNP Assembly
RMTs methylate histone arginines
FGFR2 alternative splicing
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS
Appendicular lean mass (
33097823
)
Coronary artery disease (
29212778
)
Interacting Genes
46 interacting genes:
AQR
BAG2
CDK19
CDK8
CLNS1A
CREBBP
CTDP1
EIF4A1
GLI1
GPKOW
H2AC21
HNRNPM
LSM3
NKX3-1
PCBP2
PDCD4
PPIL1
PPP1R8
PQBP1
PRKG1
PRKG2
PRMT5
QKI
RBM5
SAP30BP
SF1
SF3A1
SF3B4
SIRT7
SMAD1
SMYD1
SNRPB
SNRPC
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNRPF
SUZ12
THOC1
TOE1
UBC
YWHAB
YWHAQ
ZMYND19
ZNF207
117 interacting genes:
AKAP9
APC
CDC5L
CEACAM5
DUX4
ECPAS
FXR1
FXR2
GMCL2
GSK3A
GSK3B
HGS
HNRNPF
HNRNPH1
JUN
LENG8
LINC00624
LMO1
LMO2
LMO3
LONRF2
LYST
MAGEA6
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
OGT
PLRG1
PRRC2A
RBM4
RBM4B
SMARCB1
STAT3
SUMO2
TCERG1
TEKT4
TNKS
TRAF1
TSC1
TSGA10
U2AF1
UBC
UBE2I
USP7
WDR77
WEE2-AS1
YWHAG
ZNF207
Entrez ID
79084
4670
HPRD ID
14387
01188
Ensembl ID
ENSG00000116455
ENSG00000099783
Uniprot IDs
A0A024R0H7
Q9BQA1
P52272
Q59ES8
PDB IDs
4GQB
4X60
4X61
4X63
5C9Z
5EMJ
5EMK
5EML
5EMM
5FA5
6CKC
6K1S
6RLL
6RLQ
6UGH
6UXX
6UXY
6V0N
6V0O
6V0P
7BO7
7KIB
7KIC
7KID
7L1G
7M05
7MX7
7MXA
7MXC
7MXG
7MXN
7S0U
7S1P
7S1Q
7S1R
7S1S
7SER
7SES
7U30
7UOH
7UY1
7UYF
7ZUP
7ZUQ
7ZUU
7ZUY
7ZV2
7ZVL
7ZVU
8CSG
8CTB
8CYI
8G1U
8VEO
8VET
8VEU
8VEW
8VEX
8VEY
8X6L
9C10
9DOD
9E3A
9E3B
9EYU
9EYV
9EYW
9EYX
9MGL
9MGM
9MGN
9MGP
9MGQ
9MGR
9N3N
9N3O
9N3P
9N3Q
9N3R
2DGV
2DH9
2DO0
2OT8
Enriched GO Terms of Interacting Partners
?
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Spliceosomal Complex
RNA Splicing
MRNA Processing
MRNA Metabolic Process
Methylosome
RNA Processing
RNA Metabolic Process
Spliceosomal Complex Assembly
PICln-Sm Protein Complex
Catalytic Step 2 Spliceosome
U2-type Prespliceosome Assembly
Spliceosomal SnRNP Assembly
U2 SnRNP
Protein-RNA Complex Assembly
Nucleic Acid Metabolic Process
U2-type Spliceosomal Complex
RNA Binding
7-methylguanosine Cap Hypermethylation
U2-type Catalytic Step 2 Spliceosome
U2-type Precatalytic Spliceosome
Nucleoplasm
U1 SnRNP
Nucleus
U4 SnRNP
U12-type Spliceosomal Complex
Nucleobase-containing Compound Metabolic Process
Small Nuclear Ribonucleoprotein Complex
SMN-Sm Protein Complex
Precatalytic Spliceosome
U5 SnRNP
U4/U6 X U5 Tri-snRNP Complex
Macromolecule Metabolic Process
U7 SnRNP
Ribonucleoprotein Complex
MRNA Binding
Macromolecule Methylation
Methylation
RNA Methylation
Commitment Complex
Protein-containing Complex Assembly
Nucleic Acid Binding
Protein-containing Complex Organization
RNA Modification
CGMP-dependent Protein Kinase Activity
MRNA Cis Splicing, Via Spliceosome
U2-type Prespliceosome
Telomerase Holoenzyme Complex
Histone Pre-mRNA DCP Binding
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA 3'-UTR Binding
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Extracellular Vesicle
Negative Regulation Of Translation
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
MRNA Destabilization
Positive Regulation Of MRNA Catabolic Process
RNA Destabilization
Positive Regulation Of MRNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Translation
Negative Regulation Of Cell Migration
Regulation Of Metabolic Process
Negative Regulation Of Cell Motility
Negative Regulation Of Locomotion
Negative Regulation Of Angiogenesis
Negative Regulation Of Cytokine Production
Negative Regulation Of Vasculature Development
Regulation Of Angiogenesis
Regulation Of MRNA Stability
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of Vasculature Development
Regulation Of RNA Stability
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Multicellular Organismal Process
Negative Regulation Of Developmental Process
Regulation Of MRNA Metabolic Process
Negative Regulation Of Signal Transduction
Regulation Of Cell Migration
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Cell Motility
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Locomotion
Regulation Of Cellular Response To Growth Factor Stimulus
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