PPIL1 and SF3B3

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		PPIL1	SF3B3
Gene Name		peptidylprolyl isomerase (cyclophilin)-like 1	splicing factor 3b, subunit 3, 130kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing Protein Complex Assembly RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: CPSF6 GADD45G HNRNPA1 HNRNPUL1 PPP1R8 PRR22 RBM42 RIMBP3 SF3B3 SNW1 SRPK1 SRPK2 TCF4 THOC5 WDR77	27 interactors: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579
Entrez ID		51645	23450
HPRD ID		03194	12027
Ensembl ID		ENSG00000137168
Uniprot IDs		Q9Y3C6	A8K6V3 Q15393
PDB IDs		1XWN 2K7N 2X7K
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Viral Process Positive Regulation Of Viral Genome Replication Regulation Of Viral Process Regulation Of RNA Metabolic Process Viral Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Viral Genome Replication Nucleocytoplasmic Transport Nuclear Transport Nuclear Speck Organization Regulation Of Viral Genome Replication RNA Export From Nucleus Negative Regulation Of Viral Process Cell Differentiation Regulation Of Metabolic Process Positive Regulation Of Vitamin D Receptor Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Regulation Of Cell Cycle Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Nuclear Export MRNA Transport Nucleus Organization Nuclear Import Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint Maintenance Of DNA Repeat Elements Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Cellular Component Assembly Cellular Metabolic Process RNA Transport RNA Localization Regulation Of Vitamin D Receptor Signaling Pathway	RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Shape Regulation Of Cell Death Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Process Response To Transforming Growth Factor Beta Positive Regulation Of Apoptotic Signaling Pathway Respiratory Burst After Phagocytosis Negative Regulation Of Thymidylate Synthase Biosynthetic Process Negative Regulation Of Potassium Ion Export Cardiac Muscle Contraction Regulation Of Transcription From RNA Polymerase II Promoter Metabolic Process Heart Contraction Positive Regulation Of Response To DNA Damage Stimulus Peptidyl-amino Acid Modification Threonylcarbamoyladenosine Biosynthetic Process Leukocyte Migration Involved In Immune Response Regulation Of Heart Rate By Hormone N-acetylmannosamine Metabolic Process Response To Organic Substance Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Ossification Response To Growth Factor Positive Regulation Of Cell Death Actin Polymerization-dependent Cell Motility Striated Muscle Contraction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Peptide Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway N-acetylneuraminate Catabolic Process
Tagcloud ?			advance albeit ascertain atlas cohorts document doi dx endocrine fulvestrant lcc2 lcc9 mcf modern modpathol november oncotype online paraffin parts publication publicly qrt sets sf3b1 splicing tamoxifen
Tagcloud (Difference) ?			advance albeit ascertain atlas cohorts document doi dx endocrine fulvestrant lcc2 lcc9 mcf modern modpathol november oncotype online paraffin parts publication publicly qrt sets sf3b1 splicing tamoxifen
Tagcloud (Intersection) ?