PPIL1 and PPP1R8

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		PPIL1	PPP1R8
Gene Name		peptidylprolyl isomerase (cyclophilin)-like 1	protein phosphatase 1, regulatory subunit 8
Image
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding	DNA Binding RNA Binding Endonuclease Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Type 1 Regulator Activity Ribonuclease E Activity
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding	Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing RNA Catabolic Process Cell Proliferation RNA Splicing Negative Regulation Of Catalytic Activity RNA Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: CPSF6 GADD45G HNRNPA1 HNRNPUL1 PPP1R8 PRR22 RBM42 RIMBP3 SF3B3 SNW1 SRPK1 SRPK2 TCF4 THOC5 WDR77	24 interactors: APP APPBP2 C14orf1 CDC5L CRMP1 CSNK2A1 CSNK2A2 CTNNBL1 EED FBXO25 GBP2 HDAC2 HMGA1 LYN MELK PPIL1 PPP1CA PPP1CC PRKACA RBM48 SETDB1 SF3B1 STC2 WDR77
Entrez ID		51645	5511
HPRD ID		03194	04028
Ensembl ID		ENSG00000137168	ENSG00000117751
Uniprot IDs		Q9Y3C6	Q12972 Q6ICT4
PDB IDs		1XWN 2K7N 2X7K	3V4Y
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Viral Process Positive Regulation Of Viral Genome Replication Regulation Of Viral Process Regulation Of RNA Metabolic Process Viral Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Viral Genome Replication Nucleocytoplasmic Transport Nuclear Transport Nuclear Speck Organization Regulation Of Viral Genome Replication RNA Export From Nucleus Negative Regulation Of Viral Process Cell Differentiation Regulation Of Metabolic Process Positive Regulation Of Vitamin D Receptor Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Regulation Of Cell Cycle Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Nuclear Export MRNA Transport Nucleus Organization Nuclear Import Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint Maintenance Of DNA Repeat Elements Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Cellular Component Assembly Cellular Metabolic Process RNA Transport RNA Localization Regulation Of Vitamin D Receptor Signaling Pathway	Response To External Stimulus Triglyceride Catabolic Process Cellular Protein Modification Process Acylglycerol Catabolic Process MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression MRNA Metabolic Process RNA Metabolic Process RNA Processing RNA Splicing Chemotaxis Developmental Process Multicellular Organismal Development System Development Axon Guidance Cellular Protein Metabolic Process Chromatin Organization Response To Abiotic Stimulus Circadian Regulation Of Gene Expression Metabolic Process Regulation Of Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Process Neuron Projection Development Cellular Metabolic Process Triglyceride Metabolic Process Regulation Of Platelet Aggregation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Axonogenesis Anatomical Structure Development Neutral Lipid Metabolic Process Axon Development Rhythmic Process Regulation Of Cell Cycle Cell Cycle Cellular Nitrogen Compound Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Chromatin Modification Neuron Development Entrainment Of Circadian Clock By Photoperiod Apoptotic Process Response To Light Stimulus Photoperiodism Entrainment Of Circadian Clock Programmed Cell Death Chromosome Organization
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