PPIL1 and HNRNPUL1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, two hybrid)

		PPIL1	HNRNPUL1
Description		peptidylprolyl isomerase like 1	heterogeneous nuclear ribonucleoprotein U like 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Synapse Ribonucleoprotein Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Isomerase Activity Disordered Domain Specific Binding	RNA Binding Protein Binding Enzyme Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization MRNA Processing Protein Folding RNA Splicing Embryonic Brain Development	Alternative MRNA Splicing, Via Spliceosome RNA Processing Response To Virus
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576) Heart rate ( 28610988) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise ( 29769521) Heart rate variability traits (pvRSA/HF) ( 28613276) Heart rate variability traits (RMSSD) ( 28613276) Heart rate variability traits (SDNN) ( 28613276) Resting heart rate ( 27798624) Weight ( 28552196)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 28869591) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		25 interacting genes: COL17A1 CPSF6 DDIT4L GADD45G HNRNPA1 HNRNPUL1 KPRP LHX2 LNX2 N4BP2L2 POU6F2 PPP1R8 PRR22 PRR35 RBM42 RIMBP3 SF3B3 SNW1 SPDYE4 SRPK1 SRPK2 TCF4 THOC5 UFL1 WDR77	56 interacting genes: BRD7 CEBPA CRMP1 DMRTB1 DZIP3 EP300 ERG ERG28 EWSR1 FOXP1 FXR1 GIT2 HNRNPF HNRNPH2 HNRNPH3 IL7R ITCH KLHDC7B MAPK1IP1L MARS1 MED31 NEDD4 NXF1 NXF2 NXF3 PIAS2 PIAS4 PPIL1 PPP1R13B PRMT1 PRMT2 PRPF40A PTEN RBM22 RBM4 RBM4B ROPN1 RPA1 RPA2 SF1 SF3B4 SMN1 SMN2 SNRPB2 SNRPC SORBS3 SRSF9 TGM2 TLX3 TMEM132D TP53 TP53BP2 VPS37C WWP2 YAP1 ZNF207
Entrez ID		51645	11100
HPRD ID		03194	10428
Ensembl ID		ENSG00000137168	ENSG00000105323
Uniprot IDs		Q9Y3C6	A0A0A0MRA5 A8K3W4 B7Z4B8 Q9BUJ2
PDB IDs		1XWN 2K7N 2X7K 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7QTT 7W59 7W5A 7W5B 8C6J 8CH6 8I0S 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD	1ZRJ
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing Regulation Of RNA Splicing MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing RNA Processing Spliceosomal Complex Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Spliceosomal Complex Assembly Nucleic Acid Metabolic Process RNA Binding Protein-RNA Complex Assembly Catalytic Step 2 Spliceosome Nuclear Speck Nucleobase-containing Compound Metabolic Process Nucleus MRNA Binding Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Viral Genome Replication Cell Differentiation Ribonuclease E Activity Exon-exon Junction Complex Binding UFM1 Ligase Activity Oocyte Axis Specification Regulation Of RNA Metabolic Process Protein-containing Complex Assembly Positive Regulation Of RNA Splicing Negative Regulation Of Viral Genome Replication	Nucleoplasm RNA Splicing Nucleus Nucleic Acid Binding RNA Binding MRNA Processing RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing Spliceosomal Complex Macromolecule Metabolic Process Spliceosomal Complex Assembly Nuclear RNA Export Factor Complex PML Body Negative Regulation Of Cell Cycle Regulation Of RNA Splicing Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition P53 Binding Transcription Coregulator Activity Protein-RNA Complex Assembly Regulation Of Androgen Receptor Signaling Pathway Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition MRNA Binding MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Chromatin U1 SnRNP Protein-containing Complex Assembly Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Entrainment Of Circadian Clock By Photoperiod Poly(A)+ MRNA Export From Nucleus Cajal Body Regulation Of Cell Development Negative Regulation Of Mitotic Cell Cycle Nuclear Matrix Circadian Rhythm Regulation Of Macromolecule Metabolic Process Nuclear Androgen Receptor Binding
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