WDR77 and SNRPF

Number of citations of the paper that reports this interaction (PMID 11756452)
51

Data Source:
HPRD (in vitro)

		WDR77	SNRPF
Gene Name		WD repeat domain 77	small nuclear ribonucleoprotein polypeptide F
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome	Nucleoplasm Spliceosomal Complex U7 SnRNP U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity	RNA Binding Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Gene Expression NcRNA Metabolic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing NcRNA Metabolic Process
Pathways		Chromatin modifying enzymes snRNP Assembly Chromatin organization Metabolism of non-coding RNA RMTs methylate histone arginines	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Metabolism of non-coding RNA mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs snRNP Assembly Processing of Capped Intronless Pre-mRNA SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: AQR BAG2 COPRS CTDP1 GPKOW HIST2H2AB HNRNPM LSM3 NKX3-1 PCBP2 PPIL1 PPP1R8 PQBP1 PRMT5 QKI RBM5 SAP30BP SF1 SF3A1 SF3B4 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZNF207	22 interactors: CLNS1A COIL DDX20 GEMIN5 GEMIN6 HOMER3 IKZF1 IL7R LNX1 LSM5 LSM6 LSM7 PSMA3 PUF60 SMN2 SNRPA1 SNRPD2 SNRPE SNRPG SRRT SRSF5 WDR77
Entrez ID		79084	6636
HPRD ID		14387	04645
Ensembl ID		ENSG00000116455
Uniprot IDs		B4DP38 Q9BQA1	P62306
PDB IDs		4GQB	1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing MRNA Metabolic Process Gene Expression RNA Metabolic Process Ribonucleoprotein Complex Assembly Spliceosomal SnRNP Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Transcription, DNA-templated Histone MRNA Metabolic Process RNA Biosynthetic Process Cellular Metabolic Process Cellular Component Assembly NcRNA Metabolic Process Termination Of RNA Polymerase II Transcription DNA-templated Transcription, Termination MRNA 3'-end Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA 3'-end Processing MRNA 3'-splice Site Recognition Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Histone Methylation Regulation Of RNA Metabolic Process MRNA Splice Site Selection Biosynthetic Process Histone H4-R3 Methylation Protein Methylation Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Alternative MRNA Splicing, Via Spliceosome Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of RNA Splicing Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Cellular Macromolecular Complex Assembly Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Component Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Termination Of RNA Polymerase II Transcription Cellular Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay DNA-templated Transcription, Termination MRNA 3'-end Processing Lymph Node Development RNA 3'-end Processing Histone MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Neutrophil Differentiation Metabolic Process Interleukin-7-mediated Signaling Pathway Cellular Process Positive Regulation Of T Cell Differentiation Positive Regulation Of Lymphocyte Differentiation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of T Cell Mediated Cytotoxicity Primary MiRNA Processing Regulation Of T Cell Differentiation Positive Regulation Of NK T Cell Differentiation Aromatic Compound Catabolic Process Positive Regulation Of Granulocyte Differentiation T Cell Differentiation Regulation Of Lymphocyte Differentiation B Cell Activation
Tagcloud ?		androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 ncoa4 p44 pca promotion spliced suppressive switch switches tblr1 versions
Tagcloud (Difference) ?		androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 ncoa4 p44 pca promotion spliced suppressive switch switches tblr1 versions
Tagcloud (Intersection) ?