PPIL1

Name	peptidylprolyl isomerase like 1
Structure
Interactors	25 interactors: COL17A1 CPSF6 DDIT4L GADD45G HNRNPA1 HNRNPUL1 KPRP LHX2 LNX2 N4BP2L2 POU6F2 PPP1R8 PRR22 PRR35 RBM42 RIMBP3 SF3B3 SNW1 SPDYE4 SRPK1 SRPK2 TCF4 THOC5 UFL1 WDR77
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Isomerase Activity Disordered Domain Specific Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization MRNA Processing Protein Folding RNA Splicing Embryonic Brain Development
Pathways	mRNA Splicing - Major Pathway
GWAS	Acne (severe) ( 24927181 ) Blood protein levels ( 30072576 ) Heart rate ( 28610988 ) Heart rate response to exercise ( 29769521 ) Heart rate response to recovery post exercise ( 29769521 ) Heart rate variability traits (pvRSA/HF) ( 28613276 ) Heart rate variability traits (RMSSD) ( 28613276 ) Heart rate variability traits (SDNN) ( 28613276 ) Resting heart rate ( 27798624 ) Weight ( 28552196 )
Entrez ID	51645
HPRD ID	03194
Ensembl ID	ENSG00000137168
Uniprot IDs	Q9Y3C6
PDB IDs	1XWN 2K7N 2X7K 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7QTT 7W59 7W5A 7W5B 8C6J 8CH6 8I0S 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD
GO Terms Enriched among Interactors ?	MRNA Processing RNA Splicing Regulation Of RNA Splicing MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing RNA Processing Spliceosomal Complex Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Spliceosomal Complex Assembly Nucleic Acid Metabolic Process RNA Binding Protein-RNA Complex Assembly Catalytic Step 2 Spliceosome Nuclear Speck Nucleobase-containing Compound Metabolic Process Nucleus MRNA Binding Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Viral Genome Replication Cell Differentiation Ribonuclease E Activity Exon-exon Junction Complex Binding UFM1 Ligase Activity Oocyte Axis Specification Regulation Of RNA Metabolic Process Protein-containing Complex Assembly Positive Regulation Of RNA Splicing Negative Regulation Of Viral Genome Replication