PPIL1 and THOC5

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		PPIL1	THOC5
Gene Name		peptidylprolyl isomerase (cyclophilin)-like 1	THO complex 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding	MRNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding	Cell Morphogenesis Blastocyst Development MRNA Processing MRNA Export From Nucleus RNA Splicing Regulation Of MRNA Export From Nucleus Stem Cell Division Monocyte Differentiation Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Macrophage Differentiation Viral MRNA Export From Host Cell Nucleus Primitive Hemopoiesis Negative Regulation Of DNA Damage Checkpoint Regulation Of Stem Cell Division
Pathways
Drugs
Diseases
GWAS			Carotid atherosclerosis in HIV infection ( 20009918)
Protein-Protein Interactions		15 interactors: CPSF6 GADD45G HNRNPA1 HNRNPUL1 PPP1R8 PRR22 RBM42 RIMBP3 SF3B3 SNW1 SRPK1 SRPK2 TCF4 THOC5 WDR77	11 interactors: CSF1R CSNK2A1 DDX39B LIG4 LSM3 NXF1 PPIL1 PRKCA THOC1 THOC7 ZNF830
Entrez ID		51645	8563
HPRD ID		03194	16650
Ensembl ID		ENSG00000137168	ENSG00000100296
Uniprot IDs		Q9Y3C6	Q13769
PDB IDs		1XWN 2K7N 2X7K
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Viral Process Positive Regulation Of Viral Genome Replication Regulation Of Viral Process Regulation Of RNA Metabolic Process Viral Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Viral Genome Replication Nucleocytoplasmic Transport Nuclear Transport Nuclear Speck Organization Regulation Of Viral Genome Replication RNA Export From Nucleus Negative Regulation Of Viral Process Cell Differentiation Regulation Of Metabolic Process Positive Regulation Of Vitamin D Receptor Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Regulation Of Cell Cycle Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Nuclear Export MRNA Transport Nucleus Organization Nuclear Import Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint Maintenance Of DNA Repeat Elements Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Cellular Component Assembly Cellular Metabolic Process RNA Transport RNA Localization Regulation Of Vitamin D Receptor Signaling Pathway	Viral MRNA Export From Host Cell Nucleus MRNA Export From Nucleus RNA Export From Nucleus MRNA Transport Nuclear Export Intracellular Transport Of Virus RNA Splicing RNA Transport RNA Localization MRNA Processing Negative Regulation Of DNA Damage Checkpoint MRNA Metabolic Process Viral Process RNA Processing Nucleocytoplasmic Transport Nuclear Transport Regulation Of DNA Damage Checkpoint Gene Expression Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Positive Regulation Of DNA-templated Transcription, Elongation Viral Life Cycle Regulation Of Cell Cycle Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cytoplasmic Transport DNA Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Proliferation DNA Ligation Involved In DNA Recombination Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Isotype Switching To IgA Isotypes Nitrogen Compound Metabolic Process Apoptotic Process Regulation Of Mitotic Cell Cycle Programmed Cell Death Histone H3-T6 Phosphorylation Macrophage Colony-stimulating Factor Signaling Pathway Cell Death Death DNA-dependent DNA Replication Regulation Of Cell Cycle Process Cellular Metabolic Process Intestinal Epithelial Structure Maintenance RNA Secondary Structure Unwinding
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