MAPRE1 and CSN3

Number of citations of the paper that reports this interaction (PMID 17350042)
10

Data Source:
BioGRID (pull down, imaging technique)

		MAPRE1	CSN3
Gene Name		microtubule-associated protein, RP/EB family, member 1	casein kappa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Microtubule Cytoplasmic Microtubule Cortical Microtubule Cytoskeleton Cell Projection Membrane Microtubule Plus-end	Extracellular Space
	Molecular Function	Protein Binding Protein C-terminus Binding Poly(A) RNA Binding Microtubule Plus-end Binding	Molecular_function
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Cell Proliferation Negative Regulation Of Microtubule Polymerization Protein Localization To Microtubule Cell Division Positive Regulation Of Microtubule Plus-end Binding	Lactation Protein Stabilization
Pathways		Mitotic Prometaphase Organelle biogenesis and maintenance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: ABCB1 APC APC2 APP AURKB BCL3 CDK5RAP2 CLASP1 CLASP2 CLIP1 COPS5 COPS8 CSN3 CYLD DCTN1 HSPA1A IKBKG KAT2B KAT5 KIF2C LMO2 LRP1 MACF1 MAPRE2 MAPRE3 NAV1 NUPR1 PDE4DIP PIK3R4 POLE2 PQBP1 PSMA1 SPDYE2 STK11 TERF1 TRAF2 TRIO TROAP TUBA1A TUBB	5 interactors: CSN2 CSNK2A2 MAPRE1 PRNP RBPMS
Entrez ID		22919	1448
HPRD ID		04379	03411
Ensembl ID		ENSG00000101367	ENSG00000171209
Uniprot IDs		B4DM33 Q15691	P07498
PDB IDs		1PA7 1TXQ 1UEG 1VKA 1WU9 1YIB 1YIG 2HKQ 2HL3 2HL5 2QJZ 2R8U 3GJO 3TQ7
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Mitotic Cell Cycle Process Cell Cycle Mitotic Cell Cycle Mitotic Nuclear Division Regulation Of Microtubule-based Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Division Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Cycle G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Cell Cycle Microtubule Cytoskeleton Organization Microtubule-based Process Response To Stimulus Organelle Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Complex Assembly Regulation Of Cytoskeleton Organization Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Microtubule Depolymerization Regulation Of Chromosome Segregation Cullin Deneddylation Cellular Localization Regulation Of Wnt Signaling Pathway Establishment Or Maintenance Of Cell Polarity Response To Radiation Protein Deneddylation Negative Regulation Of Microtubule Polymerization Or Depolymerization Cellular Component Assembly Spindle Checkpoint Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Component Organization Microtubule Bundle Formation Response To Light Stimulus Cellular Protein Complex Assembly Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Positive Regulation Of Transferase Activity	Positive Regulation Of Microtubule Plus-end Binding Cell Cycle Process Negative Regulation Of Calcineurin-NFAT Signaling Cascade Neuron Differentiation Cellular Response To Copper Ion Negative Regulation Of Calcium-mediated Signaling Protein Localization To Microtubule Cell Cycle Cullin Deneddylation Negative Regulation Of Interleukin-17 Production Regulation Of Calcineurin-NFAT Signaling Cascade Protein Deneddylation Negative Regulation Of Activated T Cell Proliferation Generation Of Neurons Axon Guidance Positive Regulation Of SMAD Protein Import Into Nucleus Neurogenesis Negative Regulation Of Microtubule Polymerization Negative Regulation Of Cell Cycle Regulation Of SMAD Protein Import Into Nucleus Negative Regulation Of Interleukin-2 Production Cellular Copper Ion Homeostasis Negative Regulation Of T Cell Receptor Signaling Pathway Response To Copper Ion Protein Localization To Cytoskeleton Regulation Of Transcription, DNA-templated Copper Ion Homeostasis Axonogenesis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Regulation Of RNA Metabolic Process Axon Development Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of Cellular Metabolic Process Chemotaxis Regulation Of Microtubule Polymerization Regulation Of Protein Metabolic Process Neuron Projection Morphogenesis Negative Regulation Of Interferon-gamma Production Regulation Of Activated T Cell Proliferation Regulation Of Gene Expression Mitotic Cell Cycle Process Nervous System Development Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Potassium Ion Transmembrane Transport Mitotic Spindle Checkpoint Cell Morphogenesis Involved In Differentiation Cell Proliferation
Tagcloud ?		akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant	0x 1x 25x 2x 4ebp1 4x 5x 8x arg arginine bovine casein conditionally csn1s csn1s1 csn1s2 csn2 devoid except excess experimental gland mammary mtor output resemble s6k stat5 true
Tagcloud (Difference) ?		akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant	0x 1x 25x 2x 4ebp1 4x 5x 8x arg arginine bovine casein conditionally csn1s csn1s1 csn1s2 csn2 devoid except excess experimental gland mammary mtor output resemble s6k stat5 true
Tagcloud (Intersection) ?