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MAPRE1 and APC2
Number of citations of the paper that reports this interaction (PubMedID
10644998
)
0
Data Source:
HPRD
(in vitro)
MAPRE1
APC2
Description
microtubule associated protein RP/EB family member 1
APC regulator of Wnt signaling pathway 2
Image
No pdb structure
GO Annotations
Cellular Component
Spindle Pole
Cytoplasm
Golgi Apparatus
Centrosome
Microtubule Organizing Center
Spindle
Cytosol
Cytoskeleton
Microtubule
Cytoplasmic Microtubule
Focal Adhesion
Microtubule Cytoskeleton
Cortical Microtubule Cytoskeleton
Cell Projection Membrane
Microtubule Plus-end
Ciliary Basal Body
Cell Projection
Spindle Midzone
Mitotic Spindle Pole
Mitotic Spindle Astral Microtubule End
Mitotic Spindle Microtubule
Cytoplasm
Golgi Apparatus
Cytosol
Cytoskeleton
Microtubule
Cytoplasmic Microtubule
Actin Filament
Microtubule Cytoskeleton
Catenin Complex
Midbody
Beta-catenin Destruction Complex
Leading Edge Membrane
Lamellipodium Membrane
Filamentous Actin
Intercellular Bridge
Perinuclear Region Of Cytoplasm
Plasma Membrane Bounded Cell Projection
Molecular Function
RNA Binding
Protein Binding
Microtubule Binding
Identical Protein Binding
Cadherin Binding
Microtubule Plus-end Binding
Protein Serine/threonine Kinase Binding
Protein Binding
Beta-catenin Binding
Microtubule Binding
Gamma-catenin Binding
Biological Process
Establishment Of Mitotic Spindle Orientation
Microtubule Bundle Formation
Intracellular Protein Localization
Cell Migration
Regulation Of Microtubule Polymerization Or Depolymerization
Negative Regulation Of Microtubule Polymerization
Positive Regulation Of Microtubule Polymerization
Protein Localization To Microtubule
Microtubule Polymerization
Spindle Assembly
Cell Division
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Protein Localization To Centrosome
Protein Localization To Mitotic Spindle
Protein Localization To Astral Microtubule
Non-motile Cilium Assembly
Microtubule Cytoskeleton Organization
Cell Fate Specification
Negative Regulation Of Microtubule Depolymerization
Pattern Specification Process
Nervous System Development
Wnt Signaling Pathway
Cell Migration
Negative Regulation Of Wnt Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Activation Of GTPase Activity
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
Colorectal cancer
GWAS
Brain morphology (MOSTest) (
32665545
)
Mean platelet volume (
32888494
)
Oily fish consumption (
32066663
)
Polycystic ovary syndrome (
30566500
)
Pork consumption (
32066663
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Lean body mass (
28552196
)
Interacting Genes
50 interacting genes:
ABCB1
APC
APC2
APP
AURKB
BCL3
C20orf202
CASK
CCSER1
CDC42
CDK5RAP2
CLASP1
CLASP2
COPS5
COPS8
CSN3
CYLD
DCTN1
GTSE1
HSPA1A
IKBKG
KAT2B
KAT5
KLHL12
KLHL21
KNSTRN
LMO2
LRP1
MACF1
MARCHF7
MEOX2
NAV1
NUPR1
PAX6
PIK3R4
POLE2
PQBP1
PRPF3
PSMA1
SLAIN1
SPDYE2
SPDYE2B
SRC
SRPK2
STK11
TERF1
TRAF2
TUBA1A
TUBB
ZNF653
9 interacting genes:
AXIN2
CTNNB1
DSCAM
FXR1
MAPRE1
MAPRE3
NLGN3
SMARCA2
YAP1
Entrez ID
22919
10297
HPRD ID
04379
09802
Ensembl ID
ENSG00000101367
ENSG00000115266
Uniprot IDs
Q15691
O95996
PDB IDs
1PA7
1TXQ
1UEG
1VKA
1WU9
1YIB
1YIG
2HKQ
2HL3
2HL5
2QJZ
2R8U
3GJO
3MTU
3MUD
3TQ7
4XA1
4XA3
4XA6
5JV3
5JVM
5JVP
5JVR
5JVS
5JVU
5JX1
5WLQ
6PF2
6PFP
6YF5
6YSH
Enriched GO Terms of Interacting Partners
?
Regulation Of Microtubule-based Process
Cytoskeleton
Regulation Of Microtubule Polymerization Or Depolymerization
Microtubule
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Regulation Of Microtubule Cytoskeleton Organization
Cytoplasmic Microtubule
Microtubule Cytoskeleton Organization
Regulation Of Cell Cycle
Microtubule-based Process
Establishment Of Mitotic Spindle Localization
Regulation Of Cellular Component Organization
Regulation Of Cytoskeleton Organization
Cytoplasm
Microtubule Cytoskeleton
Regulation Of Organelle Organization
Establishment Of Organelle Localization
Organelle Localization
Mitotic Spindle
Microtubule Plus-end
Positive Regulation Of Cellular Component Organization
Cytoskeleton Organization
Regulation Of Supramolecular Fiber Organization
Establishment Of Spindle Localization
Kinetochore
Spindle Localization
Centrosome
Positive Regulation Of Supramolecular Fiber Organization
Regulation Of Microtubule Polymerization
Positive Regulation Of Microtubule Polymerization
Microtubule Binding
Cellular Component Assembly
Regulation Of Microtubule Depolymerization
Microtubule Cytoskeleton Organization Involved In Mitosis
Cytosol
Establishment Of Localization In Cell
Establishment Of Spindle Orientation
Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Protein Metabolic Process
Microtubule Plus-end Binding
Spindle
Perinuclear Region Of Cytoplasm
Protein Kinase Binding
Negative Regulation Of Cellular Component Organization
Regulation Of Cell Cycle Process
Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Cytoskeleton Organization
Regulation Of Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Cell Development
Regulation Of Multicellular Organismal Development
Positive Regulation Of Developmental Process
Positive Regulation Of Cell Differentiation
Regulation Of Nervous System Development
Regulation Of Cellular Component Organization
Positive Regulation Of Nervous System Development
Positive Regulation Of Multicellular Organismal Process
Regulation Of Organelle Organization
Regulation Of Neurogenesis
Mitotic Spindle Astral Microtubule End
Positive Regulation Of Cell Development
Regulation Of Centromeric Sister Chromatid Cohesion
Regulation Of Cell Differentiation
Regulation Of Developmental Process
Positive Regulation Of Neurogenesis
Regulation Of Microtubule Polymerization
Neuron To Neuron Synapse
Beta-catenin Destruction Complex
Regulation Of Nephron Tubule Epithelial Cell Differentiation
Cell Projection Membrane
Canonical Wnt Signaling Pathway
Regulation Of Multicellular Organismal Process
Regulation Of Microtubule Polymerization Or Depolymerization
Dorsal/ventral Axis Specification
Negative Regulation Of Microtubule Polymerization
Protein Localization To Microtubule
Regulation Of Epithelial Cell Differentiation Involved In Kidney Development
I-SMAD Binding
Regulation Of Sister Chromatid Cohesion
Developmental Growth Involved In Morphogenesis
Microtubule Plus-end Binding
Cell Development
Regulation Of Osteoblast Differentiation
Protein Serine/threonine Kinase Binding
Cellular Component Assembly
Microtubule Plus-end
Glandular Epithelial Cell Differentiation
Regulation Of Microtubule Cytoskeleton Organization
Spindle Midzone
Lung Epithelial Cell Differentiation
Lung Cell Differentiation
Germ Cell Development
Positive Regulation Of Cellular Component Organization
Negative Regulation Of Microtubule Polymerization Or Depolymerization
Regulation Of Chromosome Organization
Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Epithelial Cell Differentiation
Synapse Organization
Positive Regulation Of Stem Cell Population Maintenance
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Tagcloud (Intersection)
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