MAPRE1 and CLASP2

Number of citations of the paper that reports this interaction (PMID 23001180)
7

Data Source:
BioGRID (pull down)

		MAPRE1	CLASP2
Gene Name		microtubule-associated protein, RP/EB family, member 1	cytoplasmic linker associated protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Microtubule Cytoplasmic Microtubule Cortical Microtubule Cytoskeleton Cell Projection Membrane Microtubule Plus-end	Condensed Chromosome Kinetochore Cytoplasm Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Kinetochore Microtubule Cytosol Microtubule Cytoplasmic Microtubule Plasma Membrane Cell Cortex Membrane Ruffle Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Poly(A) RNA Binding Microtubule Plus-end Binding	Protein Binding Galactoside 2-alpha-L-fucosyltransferase Activity Microtubule Plus-end Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Cell Proliferation Negative Regulation Of Microtubule Polymerization Protein Localization To Microtubule Cell Division Positive Regulation Of Microtubule Plus-end Binding	Mitotic Cell Cycle Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Mitotic Nuclear Division Establishment Or Maintenance Of Cell Polarity Axon Guidance Microtubule Organizing Center Organization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule-based Process Microtubule Anchoring Fucosylation Cell Division
Pathways		Mitotic Prometaphase Organelle biogenesis and maintenance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes	Role of Abl in Robo-Slit signaling Mitotic Prometaphase Axon guidance Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Signaling by Robo receptor Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: ABCB1 APC APC2 APP AURKB BCL3 CDK5RAP2 CLASP1 CLASP2 CLIP1 COPS5 COPS8 CSN3 CYLD DCTN1 HSPA1A IKBKG KAT2B KAT5 KIF2C LMO2 LRP1 MACF1 MAPRE2 MAPRE3 NAV1 NUPR1 PDE4DIP PIK3R4 POLE2 PQBP1 PSMA1 SPDYE2 STK11 TERF1 TRAF2 TRIO TROAP TUBA1A TUBB	7 interactors: CLIP1 CLIP2 CSNK2A1 FEZ1 FEZ2 MAPRE1 MAPRE2
Entrez ID		22919	23122
HPRD ID		04379	12054
Ensembl ID		ENSG00000101367	ENSG00000163539
Uniprot IDs		B4DM33 Q15691	B2RTR1 O75122
PDB IDs		1PA7 1TXQ 1UEG 1VKA 1WU9 1YIB 1YIG 2HKQ 2HL3 2HL5 2QJZ 2R8U 3GJO 3TQ7
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Mitotic Cell Cycle Process Cell Cycle Mitotic Cell Cycle Mitotic Nuclear Division Regulation Of Microtubule-based Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Division Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Cycle G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Cell Cycle Microtubule Cytoskeleton Organization Microtubule-based Process Response To Stimulus Organelle Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Complex Assembly Regulation Of Cytoskeleton Organization Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Microtubule Depolymerization Regulation Of Chromosome Segregation Cullin Deneddylation Cellular Localization Regulation Of Wnt Signaling Pathway Establishment Or Maintenance Of Cell Polarity Response To Radiation Protein Deneddylation Negative Regulation Of Microtubule Polymerization Or Depolymerization Cellular Component Assembly Spindle Checkpoint Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Component Organization Microtubule Bundle Formation Response To Light Stimulus Cellular Protein Complex Assembly Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Positive Regulation Of Transferase Activity	Cell Cycle Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Microtubule Polymerization Mitotic Nuclear Division Cell Cycle Process Axon Guidance Regulation Of Microtubule Polymerization Or Depolymerization Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cellular Component Organization Protein Transport Into Plasma Membrane Raft Positive Regulation Of Microtubule Plus-end Binding Regulation Of Microtubule-based Process Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Protein Localization To Plasma Membrane Raft Regulation Of Organelle Organization Neuron Development Cell Morphogenesis Protein Localization To Microtubule Neuron Differentiation Cell Projection Organization Protein Transport Into Membrane Raft Protein Localization To Membrane Raft Locomotion Regulation Of Protein Complex Assembly Positive Regulation Of Microtubule Polymerization Negative Regulation Of Macroautophagy Negative Regulation Of Microtubule Polymerization Establishment Of Mitochondrion Localization Movement Of Cell Or Subcellular Component Protein Transport Within Lipid Bilayer Cell Division Generation Of Neurons Protein Localization To Cytoskeleton Neurogenesis Regulation Of Cytoskeleton Organization Cell Development Response To External Stimulus Negative Regulation Of Autophagy Mitochondrion Localization Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation
Tagcloud ?		akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant	1b abortive axon axonal collapsin conditioned cone counteracted crmp cytoskeletal depleted dissect glycogen gsk3beta linker map1b microtubule mimetic myelin neurite optimize outgrowth phospho prevailing regeneration regenerative regrowth scar speed
Tagcloud (Difference) ?		akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant	1b abortive axon axonal collapsin conditioned cone counteracted crmp cytoskeletal depleted dissect glycogen gsk3beta linker map1b mimetic myelin neurite optimize outgrowth phospho prevailing regeneration regenerative regrowth scar speed
Tagcloud (Intersection) ?		microtubule