Wiki-Pi
About
Search
People
Updates
Search
YWHAB and DHX15
Number of citations of the paper that reports this interaction (PubMedID
15324660
)
0
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
YWHAB
DHX15
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
DEAH-box helicase 15
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Vacuole
Vacuolar Membrane
Cytosol
Focal Adhesion
Membrane
Transcription Repressor Complex
Protein-containing Complex
Melanosome
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Nucleus
Nucleoplasm
Spliceosomal Complex
U12-type Spliceosomal Complex
Nucleolus
Nuclear Speck
U2-type Post-mRNA Release Spliceosomal Complex
Molecular Function
Protein Kinase Inhibitor Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
Enzyme Binding
Protein Domain Specific Binding
Identical Protein Binding
Histone Deacetylase Binding
Protein-containing Complex Binding
Cadherin Binding
Phosphoserine Residue Binding
Phosphoprotein Binding
Protein Sequestering Activity
Nucleotide Binding
Nucleic Acid Binding
RNA Binding
RNA Helicase Activity
Double-stranded RNA Binding
Helicase Activity
Protein Binding
ATP Binding
ATP-dependent Activity, Acting On RNA
Hydrolase Activity
ATP Hydrolysis Activity
Biological Process
Protein Targeting
Signal Transduction
Intracellular Protein Localization
Negative Regulation Of Protein Import Into Nucleus
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
MRNA Splicing, Via Spliceosome
Immune System Process
MRNA Processing
RNA Splicing
Response To Toxic Substance
Defense Response To Bacterium
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Response To Alkaloid
Innate Immune Response
Defense Response To Virus
Antiviral Innate Immune Response
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
MTOR signalling
mTORC1-mediated signalling
Frs2-mediated activation
Frs2-mediated activation
ARMS-mediated activation
Signaling by Hippo
Rap1 signalling
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
RAF activation
MAP2K and MAPK activation
Negative regulation of MAPK pathway
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF1 fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
Signaling downstream of RAS mutants
Signaling by RAF1 mutants
SHOC2 M1731 mutant abolishes MRAS complex function
Gain-of-function MRAS complexes activate RAF signaling
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Transcriptional and post-translational regulation of MITF-M expression and activity
mRNA Splicing - Major Pathway
Drugs
Copper
Phenethyl Isothiocyanate
Diseases
GWAS
Basophil count (
32888494
)
Basophil percentage of white cells (
32888494
)
Blood protein levels (
30072576
)
Breakfast cereal skipping frequency (
31190057
)
Breakfast skipping (
31190057
)
Mean platelet volume (
32888494
)
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Myopia (pathological) (
23049088
)
Pulmonary emphysema (
24383474
)
Sense of smell (
26632684
)
Interacting Genes
147 interacting genes:
ABL1
ADAM22
AFDN
AKAP13
ALS2
APP
ATP5F1A
BAD
BAX
BCL2L11
BCR
BID
BRAF
C1QBP
CAMK2A
CAMK2B
CBL
CDC25A
CDC25B
CDC25C
CDK11B
CDK14
CDKN1B
CHAF1A
CRTC2
CSNK2A1
DAPK1
DHX15
DYRK1A
EDC3
EGFR
EPB41
EPB41L1
EPB41L3
ERRFI1
EXO1
FER
FILNC1
FRMD6
GAPVD1
GEM
H3C1
HDAC5
HES1
HSP90AB1
HSPA1A
HSPA1B
HSPA5
HSPB1
IGF1R
IKBKB
ING1
INSR
IRS1
IRS2
ITGB1
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIAA0930
KIF1C
KIF23
KIF5B
KLC1
KRT18
LARP1
LYST
MAP3K3
MAPK7
MAPT
MARK2
MARK4
MDM4
MICALL1
MINK1
MLXIP
MPRIP
MST1R
MTNR1A
MTNR1B
NCAM2
NEDD4L
OSBPL3
PARD3
PARD6B
PDCL2
PDE3B
PDE4B
PI4KB
PIK3R2
PIK3R4
PRKCD
PRKCG
PRKCZ
PRPF6
PTPN3
RABGEF1
RACGAP1
RADIL
RAF1
RAI14
RALGPS2
RASGRF1
RGS3
RGS7
RIN1
RIOK1
RIPK2
RMDN3
RNPS1
RPS6KA1
SAMSN1
SKP2
SLC4A7
SLC8A1
SLC8A2
SLC8A3
SLC9A1
SNCA
SNRNP200
SON
SRC
SRRM2
SRSF10
SRSF3
STK38
STK38L
TESK1
TESK2
TH
TJP2
TNFAIP3
TPD52L1
TSC1
TSC2
TUBB
UBC
UCP2
UCP3
WDR77
WEE1
YWHAE
YWHAG
ZFP36
ZFP36L1
23 interacting genes:
AGGF1
APBB1
CAMSAP3
CEBPA
DDX42
DYSF
FXR1
GPANK1
KRT75
NKAP
NKRF
PIN1
PRPF40A
PTEN
PTP4A2
SPOP
TRA2A
UBC
USP7
WBP4
YWHAB
YWHAG
ZGPAT
Entrez ID
7529
1665
HPRD ID
03184
04553
Ensembl ID
ENSG00000166913
ENSG00000109606
Uniprot IDs
P31946
V9HWD6
O43143
PDB IDs
2BQ0
2C23
4DNK
5N10
6A5Q
6BYK
6GN0
6GN8
6GNJ
6GNK
6GNN
6HEP
8DP5
8EQ8
8EQH
5XDR
6ID1
6SH6
6SH7
8EJM
8RO2
Enriched GO Terms of Interacting Partners
?
Kinase Activity
Protein Kinase Activity
Regulation Of Intracellular Signal Transduction
Intracellular Signal Transduction
Cytosol
Protein Serine Kinase Activity
Regulation Of Cell Communication
Regulation Of Signaling
Protein Serine/threonine Kinase Activity
Regulation Of Signal Transduction
Positive Regulation Of Cell Communication
Cytoplasm
Protein Phosphorylation
ATP Binding
Positive Regulation Of Signaling
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Phosphorylation
Negative Regulation Of Signal Transduction
Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Intracellular Signal Transduction
Nucleotide Binding
Positive Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Programmed Cell Death
Regulation Of Protein Modification Process
Signal Transduction
Cellular Response To Oxygen-containing Compound
Protein Tyrosine Kinase Activity
Response To Stress
Cellular Response To Stress
Regulation Of Cell Cycle
Regulation Of Membrane Potential
Intracellular Signaling Cassette
Cellular Response To Hormone Stimulus
Cadherin Binding
Regulation Of Protein-containing Complex Assembly
Regulation Of Phosphorus Metabolic Process
Cellular Response To Insulin Stimulus
Regulation Of Protein Phosphorylation
Regulation Of Biological Quality
Plasma Membrane
Response To Insulin
Positive Regulation Of Catabolic Process
Phosphate-containing Compound Metabolic Process
Cellular Response To Peptide Hormone Stimulus
Regulation Of Phosphorylation
Nucleic Acid Binding
Nuclear Speck
Negative Regulation Of Macromolecule Metabolic Process
Phosphoserine Residue Binding
Nucleoplasm
Negative Regulation Of Metabolic Process
Nucleus
Ubiquitin Ligase Activator Activity
Negative Regulation Of Protein Metabolic Process
RNA Binding
MRNA Cis Splicing, Via Spliceosome
Proline-rich Region Binding
Protein Stabilization
U2-type Prespliceosome
Negative Regulation Of Protein Phosphorylation
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Hematopoietic Stem Cell Proliferation
Regulation Of Protein Metabolic Process
Dentate Gyrus Development
Negative Regulation Of Phosphorylation
Granulocyte Differentiation
Molecular Function Inhibitor Activity
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Primary Metabolic Process
Negative Regulation Of Cell Cycle
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Regulation Of Protein Stability
Cis-trans Isomerase Activity
Phosphoprotein Binding
Negative Regulation Of Synaptic Vesicle Clustering
Negative Regulation Of Phosphate Metabolic Process
Monocyte Activation Involved In Immune Response
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Regulation Of Protein Phosphorylation
Protein Sequestering Activity
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?