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YWHAB and BID
Number of citations of the paper that reports this interaction (PubMedID
12871587
)
0
Data Source:
HPRD
(in vitro)
YWHAB
BID
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
BH3 interacting domain death agonist
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Vacuole
Vacuolar Membrane
Cytosol
Focal Adhesion
Membrane
Transcription Repressor Complex
Protein-containing Complex
Melanosome
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Membrane
Mitochondrial Membrane
Molecular Function
Protein Kinase Inhibitor Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
Enzyme Binding
Protein Domain Specific Binding
Identical Protein Binding
Histone Deacetylase Binding
Protein-containing Complex Binding
Cadherin Binding
Phosphoserine Residue Binding
Phosphoprotein Binding
Protein Sequestering Activity
Death Receptor Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Cysteine-type Endopeptidase Regulator Activity Involved In Apoptotic Process
Biological Process
Protein Targeting
Signal Transduction
Intracellular Protein Localization
Negative Regulation Of Protein Import Into Nucleus
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Apoptotic Mitochondrial Changes
Positive Regulation Of Mitochondrial Membrane Potential
Positive Regulation Of Protein-containing Complex Assembly
Cellular Response To Stress
Intracellular Signal Transduction
Regulation Of T Cell Proliferation
Signal Transduction In Response To DNA Damage
Mitochondrial ATP Synthesis Coupled Electron Transport
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Regulation Of Epithelial Cell Proliferation
Neuron Apoptotic Process
Protein-containing Complex Assembly
Establishment Of Protein Localization To Membrane
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Extrinsic Apoptotic Signaling Pathway
Hepatocyte Apoptotic Process
Mitochondrial Outer Membrane Permeabilization
Supramolecular Fiber Organization
Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of Intracellular Signal Transduction
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Fibroblast Apoptotic Process
Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
MTOR signalling
mTORC1-mediated signalling
Frs2-mediated activation
Frs2-mediated activation
ARMS-mediated activation
Signaling by Hippo
Rap1 signalling
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
RAF activation
MAP2K and MAPK activation
Negative regulation of MAPK pathway
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF1 fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
Signaling downstream of RAS mutants
Signaling by RAF1 mutants
SHOC2 M1731 mutant abolishes MRAS complex function
Gain-of-function MRAS complexes activate RAF signaling
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Transcriptional and post-translational regulation of MITF-M expression and activity
Activation of BAD and translocation to mitochondria
Activation and oligomerization of BAK protein
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Activation, translocation and oligomerization of BAX
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Activation, myristolyation of BID and translocation to mitochondria
Drugs
Copper
Phenethyl Isothiocyanate
Diseases
GWAS
Basophil count (
32888494
)
Basophil percentage of white cells (
32888494
)
Blood protein levels (
30072576
)
Breakfast cereal skipping frequency (
31190057
)
Breakfast skipping (
31190057
)
Mean platelet volume (
32888494
)
Adult body size (
32376654
)
Diisocyanate-induced asthma (
25918132
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
Interacting Genes
147 interacting genes:
ABL1
ADAM22
AFDN
AKAP13
ALS2
APP
ATP5F1A
BAD
BAX
BCL2L11
BCR
BID
BRAF
C1QBP
CAMK2A
CAMK2B
CBL
CDC25A
CDC25B
CDC25C
CDK11B
CDK14
CDKN1B
CHAF1A
CRTC2
CSNK2A1
DAPK1
DHX15
DYRK1A
EDC3
EGFR
EPB41
EPB41L1
EPB41L3
ERRFI1
EXO1
FER
FILNC1
FRMD6
GAPVD1
GEM
H3C1
HDAC5
HES1
HSP90AB1
HSPA1A
HSPA1B
HSPA5
HSPB1
IGF1R
IKBKB
ING1
INSR
IRS1
IRS2
ITGB1
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIAA0930
KIF1C
KIF23
KIF5B
KLC1
KRT18
LARP1
LYST
MAP3K3
MAPK7
MAPT
MARK2
MARK4
MDM4
MICALL1
MINK1
MLXIP
MPRIP
MST1R
MTNR1A
MTNR1B
NCAM2
NEDD4L
OSBPL3
PARD3
PARD6B
PDCL2
PDE3B
PDE4B
PI4KB
PIK3R2
PIK3R4
PRKCD
PRKCG
PRKCZ
PRPF6
PTPN3
RABGEF1
RACGAP1
RADIL
RAF1
RAI14
RALGPS2
RASGRF1
RGS3
RGS7
RIN1
RIOK1
RIPK2
RMDN3
RNPS1
RPS6KA1
SAMSN1
SKP2
SLC4A7
SLC8A1
SLC8A2
SLC8A3
SLC9A1
SNCA
SNRNP200
SON
SRC
SRRM2
SRSF10
SRSF3
STK38
STK38L
TESK1
TESK2
TH
TJP2
TNFAIP3
TPD52L1
TSC1
TSC2
TUBB
UBC
UCP2
UCP3
WDR77
WEE1
YWHAE
YWHAG
ZFP36
ZFP36L1
36 interacting genes:
AHCYL1
BAK1
BAX
BCL2
BCL2A1
BCL2L1
BCL2L2
CAPN1
CAPN2
CASP1
CASP10
CASP2
CASP3
CASP8
CRMP1
CRNKL1
CSNK1A1
CSNK1E
CSNK2A1
CSNK2A2
CSNK2B
DDIT4L
ERG28
FBN3
GAPDH
GBP2
GZMB
MCL1
PLEKHM1
RBM48
REL
SETDB1
TLE1
TUBB2B
YWHAB
ZHX1
Entrez ID
7529
637
HPRD ID
03184
03590
Ensembl ID
ENSG00000166913
ENSG00000015475
Uniprot IDs
P31946
V9HWD6
A8ASI8
B2ZP79
B3KT21
P55957
PDB IDs
2BQ0
2C23
4DNK
5N10
6A5Q
6BYK
6GN0
6GN8
6GNJ
6GNK
6GNN
6HEP
8DP5
8EQ8
8EQH
1ZY3
2BID
2KBW
2M5B
2M5I
4BD2
4QVE
4ZEQ
4ZIG
4ZII
5AJJ
5C3F
7M5A
7M5B
7P33
7QTW
8SM5
Enriched GO Terms of Interacting Partners
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Kinase Activity
Protein Kinase Activity
Regulation Of Intracellular Signal Transduction
Intracellular Signal Transduction
Cytosol
Protein Serine Kinase Activity
Regulation Of Cell Communication
Regulation Of Signaling
Protein Serine/threonine Kinase Activity
Regulation Of Signal Transduction
Positive Regulation Of Cell Communication
Cytoplasm
Protein Phosphorylation
ATP Binding
Positive Regulation Of Signaling
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Phosphorylation
Negative Regulation Of Signal Transduction
Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Intracellular Signal Transduction
Nucleotide Binding
Positive Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Programmed Cell Death
Regulation Of Protein Modification Process
Signal Transduction
Cellular Response To Oxygen-containing Compound
Protein Tyrosine Kinase Activity
Response To Stress
Cellular Response To Stress
Regulation Of Cell Cycle
Regulation Of Membrane Potential
Intracellular Signaling Cassette
Cellular Response To Hormone Stimulus
Cadherin Binding
Regulation Of Protein-containing Complex Assembly
Regulation Of Phosphorus Metabolic Process
Cellular Response To Insulin Stimulus
Regulation Of Protein Phosphorylation
Regulation Of Biological Quality
Plasma Membrane
Response To Insulin
Positive Regulation Of Catabolic Process
Phosphate-containing Compound Metabolic Process
Cellular Response To Peptide Hormone Stimulus
Regulation Of Phosphorylation
Bcl-2 Family Protein Complex
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Release Of Cytochrome C From Mitochondria
Apoptotic Process
Cell Death
Programmed Cell Death
Channel Activity
Extrinsic Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Execution Phase Of Apoptosis
Apoptotic Mitochondrial Changes
Intrinsic Apoptotic Signaling Pathway
BH3 Domain Binding
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Apoptotic Signaling Pathway
Positive Regulation Of Neuron Apoptotic Process
Protein Kinase CK2 Complex
Mitochondrial Outer Membrane
Cysteine-type Peptidase Activity
Regulation Of Apoptotic Process
Protein Maturation
Regulation Of Programmed Cell Death
Identical Protein Binding
Leukocyte Apoptotic Process
DNA Damage Response
Regulation Of Neuron Apoptotic Process
Mitochondrial Fusion
Negative Regulation Of Anoikis
Regulation Of Autophagy
Signal Transduction
Programmed Cell Death Involved In Cell Development
Response To Cytokine
Response To Peptide
Negative Regulation Of Programmed Cell Death
Regulation Of Anoikis
Cysteine-type Endopeptidase Activity
Peptidase Activity
B Cell Homeostasis
Cytosol
Negative Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Pyroptotic Inflammatory Response
Mitochondrion Organization
Regulation Of Proteolysis
Negative Regulation Of Apoptotic Process
Regulation Of Apoptotic Signaling Pathway
Response To Stress
B Cell Apoptotic Process
Pyroptotic Inflammatory Response
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Tagcloud (Difference)
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Tagcloud (Intersection)
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