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YWHAB and ATP5F1A
Number of citations of the paper that reports this interaction (PubMedID
15324660
)
0
Data Source:
HPRD
(in vivo)
YWHAB
ATP5F1A
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
ATP synthase F1 subunit alpha
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Vacuole
Vacuolar Membrane
Cytosol
Focal Adhesion
Membrane
Transcription Repressor Complex
Protein-containing Complex
Melanosome
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Plasma Membrane
Cell Surface
Membrane
Proton-transporting Two-sector ATPase Complex
Membrane Raft
Proton-transporting ATP Synthase Complex
Extracellular Exosome
Transmembrane Transporter Complex
Molecular Function
Protein Kinase Inhibitor Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
Enzyme Binding
Protein Domain Specific Binding
Identical Protein Binding
Histone Deacetylase Binding
Protein-containing Complex Binding
Cadherin Binding
Phosphoserine Residue Binding
Phosphoprotein Binding
Protein Sequestering Activity
Nucleotide Binding
Protease Binding
RNA Binding
Protein Binding
ATP Binding
ATP Hydrolysis Activity
Adenyl Ribonucleotide Binding
MHC Class I Protein Binding
ADP Binding
Angiostatin Binding
Proton-transporting ATP Synthase Activity, Rotational Mechanism
Biological Process
Protein Targeting
Signal Transduction
Intracellular Protein Localization
Negative Regulation Of Protein Import Into Nucleus
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Endothelial Cell Proliferation
Lipid Metabolic Process
ATP Biosynthetic Process
Monoatomic Ion Transport
Response To Muscle Activity
Proton Motive Force-driven ATP Synthesis
Proton Motive Force-driven Mitochondrial ATP Synthesis
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Response To Ethanol
ATP Metabolic Process
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Proton Transmembrane Transport
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
MTOR signalling
mTORC1-mediated signalling
Frs2-mediated activation
Frs2-mediated activation
ARMS-mediated activation
Signaling by Hippo
Rap1 signalling
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
RAF activation
MAP2K and MAPK activation
Negative regulation of MAPK pathway
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF1 fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
Signaling downstream of RAS mutants
Signaling by RAF1 mutants
SHOC2 M1731 mutant abolishes MRAS complex function
Gain-of-function MRAS complexes activate RAF signaling
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Transcriptional and post-translational regulation of MITF-M expression and activity
Mitochondrial protein import
Formation of ATP by chemiosmotic coupling
Cristae formation
Mitochondrial protein degradation
Drugs
Copper
Phenethyl Isothiocyanate
Quercetin
1-ACETYL-2-CARBOXYPIPERIDINE
AUROVERTIN B
Piceatannol
N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
Artenimol
Diseases
GWAS
Basophil count (
32888494
)
Basophil percentage of white cells (
32888494
)
Blood protein levels (
30072576
)
Breakfast cereal skipping frequency (
31190057
)
Breakfast skipping (
31190057
)
Mean platelet volume (
32888494
)
Interacting Genes
147 interacting genes:
ABL1
ADAM22
AFDN
AKAP13
ALS2
APP
ATP5F1A
BAD
BAX
BCL2L11
BCR
BID
BRAF
C1QBP
CAMK2A
CAMK2B
CBL
CDC25A
CDC25B
CDC25C
CDK11B
CDK14
CDKN1B
CHAF1A
CRTC2
CSNK2A1
DAPK1
DHX15
DYRK1A
EDC3
EGFR
EPB41
EPB41L1
EPB41L3
ERRFI1
EXO1
FER
FILNC1
FRMD6
GAPVD1
GEM
H3C1
HDAC5
HES1
HSP90AB1
HSPA1A
HSPA1B
HSPA5
HSPB1
IGF1R
IKBKB
ING1
INSR
IRS1
IRS2
ITGB1
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIAA0930
KIF1C
KIF23
KIF5B
KLC1
KRT18
LARP1
LYST
MAP3K3
MAPK7
MAPT
MARK2
MARK4
MDM4
MICALL1
MINK1
MLXIP
MPRIP
MST1R
MTNR1A
MTNR1B
NCAM2
NEDD4L
OSBPL3
PARD3
PARD6B
PDCL2
PDE3B
PDE4B
PI4KB
PIK3R2
PIK3R4
PRKCD
PRKCG
PRKCZ
PRPF6
PTPN3
RABGEF1
RACGAP1
RADIL
RAF1
RAI14
RALGPS2
RASGRF1
RGS3
RGS7
RIN1
RIOK1
RIPK2
RMDN3
RNPS1
RPS6KA1
SAMSN1
SKP2
SLC4A7
SLC8A1
SLC8A2
SLC8A3
SLC9A1
SNCA
SNRNP200
SON
SRC
SRRM2
SRSF10
SRSF3
STK38
STK38L
TESK1
TESK2
TH
TJP2
TNFAIP3
TPD52L1
TSC1
TSC2
TUBB
UBC
UCP2
UCP3
WDR77
WEE1
YWHAE
YWHAG
ZFP36
ZFP36L1
24 interacting genes:
ABCC1
AIMP1
AIRE
APP
ATP5F1C
ATPAF2
CSNK2A1
FNDC3B
HSD17B10
HSPB2
LINC00941
LINC01554
NPSR1
OGT
PTEN
PTPRF
SCGN
SHBG
SMARCB1
TNK2
YWHAB
YWHAG
YWHAQ
YWHAZ
Entrez ID
7529
498
HPRD ID
03184
01258
Ensembl ID
ENSG00000166913
ENSG00000152234
Uniprot IDs
P31946
V9HWD6
P25705
V9HW26
PDB IDs
2BQ0
2C23
4DNK
5N10
6A5Q
6BYK
6GN0
6GN8
6GNJ
6GNK
6GNN
6HEP
8DP5
8EQ8
8EQH
8H9E
8H9I
8H9L
8H9P
8H9S
8H9T
8H9U
8H9V
8KI3
Enriched GO Terms of Interacting Partners
?
Kinase Activity
Protein Kinase Activity
Regulation Of Intracellular Signal Transduction
Intracellular Signal Transduction
Cytosol
Protein Serine Kinase Activity
Regulation Of Cell Communication
Regulation Of Signaling
Protein Serine/threonine Kinase Activity
Regulation Of Signal Transduction
Positive Regulation Of Cell Communication
Cytoplasm
Protein Phosphorylation
ATP Binding
Positive Regulation Of Signaling
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Phosphorylation
Negative Regulation Of Signal Transduction
Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Intracellular Signal Transduction
Nucleotide Binding
Positive Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Programmed Cell Death
Regulation Of Protein Modification Process
Signal Transduction
Cellular Response To Oxygen-containing Compound
Protein Tyrosine Kinase Activity
Response To Stress
Cellular Response To Stress
Regulation Of Cell Cycle
Regulation Of Membrane Potential
Intracellular Signaling Cassette
Cellular Response To Hormone Stimulus
Cadherin Binding
Regulation Of Protein-containing Complex Assembly
Regulation Of Phosphorus Metabolic Process
Cellular Response To Insulin Stimulus
Regulation Of Protein Phosphorylation
Regulation Of Biological Quality
Plasma Membrane
Response To Insulin
Positive Regulation Of Catabolic Process
Phosphate-containing Compound Metabolic Process
Cellular Response To Peptide Hormone Stimulus
Regulation Of Phosphorylation
Negative Regulation Of Protein Localization To Nucleus
Protein Targeting
Negative Regulation Of Translational Initiation
Phosphoserine Residue Binding
Protein Sequestering Activity
Identical Protein Binding
TORC1 Signaling
Regulation Of Translation
Protein Domain Specific Binding
TOR Signaling
Protein Localization To Vacuole
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Regulation Of Translational Initiation
Sin3-type Complex
Regulation Of TORC1 Signaling
Post-transcriptional Regulation Of Gene Expression
Central Tolerance Induction To Self Antigen
Peripheral T Cell Tolerance Induction
Positive Regulation Of Transcription By RNA Polymerase II
Amyloid-beta Complex
Regulation Of Phosphorus Metabolic Process
Growth Cone Lamellipodium
Positive Regulation Of Protein Metabolic Process
Regulation Of Response To Calcium Ion
Positive Regulation Of Excitatory Postsynaptic Potential
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Regulation Of Protein Localization To Nucleus
Positive Regulation Of Signal Transduction
Reproductive Behavior
Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity
Chenodeoxycholate 7-alpha-dehydrogenase (NAD+) Activity
3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity
Cholate 7-alpha-dehydrogenase (NAD+) Activity
Ursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity
Negative Regulation Of Synaptic Vesicle Clustering
Chondroitin Sulfate Proteoglycan Binding
Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Regulation Of TOR Signaling
Protein N-acetylglucosaminyltransferase Complex
Negative Regulation Of Non-canonical Inflammasome Complex Assembly
Positive Regulation Of Glucagon Secretion
Negative Regulation Of Defecation
Synapse
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Tagcloud (Intersection)
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