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VCP and WDYHV1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
VCP
WDYHV1
Gene Name
valosin containing protein
WDYHV motif containing 1
Image
Gene Ontology Annotations
Cellular Component
Proteasome Complex
Hrd1p Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Lipid Particle
Cytosol
Site Of Double-strand Break
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Nucleus
Cytosol
Molecular Function
Receptor Binding
Protein Binding
ATP Binding
Lipid Binding
ATPase Activity
Protein Phosphatase Binding
Protein Domain Specific Binding
Polyubiquitin Binding
Protein Complex Binding
Deubiquitinase Activator Activity
Identical Protein Binding
ADP Binding
Poly(A) RNA Binding
Ubiquitin-specific Protease Binding
Protein Binding
Protein-N-terminal Glutamine Amidohydrolase Activity
Biological Process
DNA Repair
Double-strand Break Repair
ER To Golgi Vesicle-mediated Transport
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cellular Response To DNA Damage Stimulus
Protein Ubiquitination
Protein N-linked Glycosylation Via Asparagine
Translesion Synthesis
ER-associated Ubiquitin-dependent Protein Catabolic Process
Endoplasmic Reticulum Unfolded Protein Response
Retrograde Protein Transport, ER To Cytosol
Positive Regulation Of Protein Complex Assembly
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Hexamerization
Cellular Response To Heat
Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Establishment Of Protein Localization
Positive Regulation Of Protein Catabolic Process
Protein Homooligomerization
Aggresome Assembly
Positive Regulation Of Protein K63-linked Deubiquitination
Positive Regulation Of Lys63-specific Deubiquitinase Activity
Cellular Protein Modification Process
Pathways
HSF1 activation
Hedgehog ligand biogenesis
Processing-defective Hh variants abrogate ligand secretion
Hh ligand biogenesis disease
Signaling by Hedgehog
Cellular response to heat stress
Drugs
Diseases
GWAS
Protein-Protein Interactions
72 interactors:
AMFR
AR
ASPSCR1
ATG5
ATXN1
ATXN3
ATXN7
BRCA1
BRSK2
CAV1
CEP19
CRMP1
DERL1
DGCR6
DTNB
FAM104A
GZMK
HDAC6
HERPUD1
HTT
INSIG1
INSIG2
JAK2
LNX1
MAPK8IP2
NDRG1
NF1
NFKBIA
NGLY1
NPLOC4
NSFL1C
NUB1
OTULIN
PLAA
PRKCD
PSMA1
PSMA7
PSMC1
PTPN3
RNF19A
RNF31
RNF8
RPL9
RPS6KA1
SH2D2A
SIK2
STUB1
STX5
SUMO4
SVIP
SYVN1
TOM1L1
TOMM34
UBE4A
UBE4B
UBOX5
UBQLN1
UBXN1
UBXN2A
UBXN2B
UBXN6
UFD1L
VCPIP1
VCPKMT
VIMP
WAC
WBSCR22
WDYHV1
WRN
YOD1
YWHAZ
ZFAND2B
88 interactors:
ACTB
ACTG1
AMOT
AMOTL2
APIP
ASL
BIRC2
BLMH
BLOC1S6
C1orf50
CAPN3
CBFA2T2
CCDC102B
CCDC184
CDA
CDR2
COIL
CRYAA
CTH
DAB1
DCTPP1
DHPS
EDARADD
EIF2B1
ETV6
FTH1
GAS7
GMDS
GNMT
GOLGA2
HPRT1
HSD17B14
JUP
KCNH1
KCTD1
KLHL12
KRT31
KRTAP10-5
KRTAP10-7
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-4
LONRF1
LZTFL1
LZTS2
MAGEA11
MARCH10
MDFI
MIF
MTUS2
NCOA5
NECAB2
NME1
NPL
NT5C1A
NUDT14
PCBD1
PNMA1
PNMA5
PPCDC
PRMT1
PRPS2
PTS
PYGM
RABAC1
RAD54L
RBBP8
RBPMS
RPIA
SEPT3
SFN
SIAH1
SMN1
STX11
THAP1
TMEM239
TNR
TOLLIP
TRIM27
TRIM54
TRIP13
TSC22D1
VAC14
VCP
XIAP
ZBTB8A
ZNF341
Entrez ID
7415
55093
HPRD ID
03013
07653
Ensembl ID
ENSG00000165280
ENSG00000156795
Uniprot IDs
P55072
Q96IF9
Q96HA8
PDB IDs
3EBB
3HU1
3HU2
3HU3
3QC8
3QQ7
3QQ8
3QWZ
3TIW
3C9Q
Enriched GO Terms of Interacting Partners
?
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Cellular Response To Stress
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Protein Metabolic Process
Proteolysis
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Response To Stress
Catabolic Process
Protein Metabolic Process
Protein Polyubiquitination
Cellular Metabolic Process
Regulation Of Protein Ubiquitination
Cellular Protein Modification Process
Cellular Response To Topologically Incorrect Protein
ER-nucleus Signaling Pathway
Golgi Organization
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Cell Communication
Regulation Of Protein Catabolic Process
Response To Endoplasmic Reticulum Stress
ER-associated Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Stimulus
Negative Regulation Of Apoptotic Process
Regulation Of Proteolysis
Negative Regulation Of Programmed Cell Death
Regulation Of Cell Death
Negative Regulation Of Cellular Protein Metabolic Process
Apoptotic Process
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Metabolic Process
Negative Regulation Of Cell Death
Positive Regulation Of Cellular Metabolic Process
Regulation Of Apoptotic Process
Cellular Response To Unfolded Protein
Programmed Cell Death
Negative Regulation Of Protein Metabolic Process
Cell Death
Death
Negative Regulation Of Signal Transduction
Response To Stimulus
Response To Unfolded Protein
Negative Regulation Of Signaling
Protein Oligomerization
Protein Complex Assembly
Protein Homooligomerization
Cellular Component Assembly
Protein Homotetramerization
Protein Tetramerization
Nucleobase-containing Small Molecule Metabolic Process
Nucleoside Metabolic Process
Catabolic Process
Cellular Nitrogen Compound Metabolic Process
Purine Nucleoside Metabolic Process
Anatomical Structure Development
Small Molecule Metabolic Process
Developmental Process
Biosynthetic Process
Cell Differentiation
Nitrogen Compound Metabolic Process
Regulation Of Cellular Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Apoptotic Process
Cellular Metabolic Process
Purine Nucleoside Monophosphate Catabolic Process
Regulation Of Cell Death
Tetrahydrobiopterin Biosynthetic Process
Cell Development
Nucleotide Metabolic Process
System Development
Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Ubiquitination
Sulfur Amino Acid Metabolic Process
Multicellular Organismal Development
Aromatic Compound Catabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Modification By Small Protein Conjugation
Cofactor Metabolic Process
Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Neuron Projection Development
Regulation Of Metabolic Process
Organophosphate Metabolic Process
Cellular Modified Amino Acid Metabolic Process
Regulation Of Cellular Localization
Membrane Organization
Response To Stimulus
Organophosphate Catabolic Process
Double-strand Break Repair
Cellular Process
S-adenosylmethionine Metabolic Process
Pyrimidine Nucleoside Metabolic Process
Tagcloud
?
17q11
3q28
9pter
ap2
ap50
aps
blots
clapb1
clapm1
clathrin
coated
denoted
designated
dnas
endocytosis
lattice
locations
mapped
maps
oligonucleotide
porcine
primers
probe
q12
q34
rodent
served
stoichiometric
triskelia
Tagcloud (Difference)
?
17q11
3q28
9pter
ap2
ap50
aps
blots
clapb1
clapm1
clathrin
coated
denoted
designated
dnas
endocytosis
lattice
locations
mapped
maps
oligonucleotide
porcine
primers
probe
q12
q34
rodent
served
stoichiometric
triskelia
Tagcloud (Intersection)
?