NTAQ1 and PFDN5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NTAQ1	PFDN5
Description		N-terminal glutamine amidase 1	prefoldin subunit 5
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol Prefoldin Complex Protein-containing Complex Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Protein-N-terminal Asparagine Amidohydrolase Activity Hydrolase Activity Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Protein-N-terminal Glutamine Amidohydrolase Activity	Amyloid-beta Binding Transcription Corepressor Activity Protein Binding Unfolded Protein Binding
	Biological Process	Protein Modification Process	Regulation Of DNA-templated Transcription Protein Folding Negative Regulation Of DNA-templated Transcription Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Amyloid Fibril Formation RNA Polymerase I Assembly RNA Polymerase II Core Complex Assembly RNA Polymerase III Assembly
Pathways			Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS
Interacting Genes		379 interacting genes: - AARD ACD ACOT13 ACTB ACTG1 ACTN2 ACY1 ADAMTSL4 AGR2 AGR3 AIMP2 AKIRIN2 AMOT AMOTL2 AMPD2 ANKRD11 ANKRD36B AOC1 APIP ARID4B ARL6IP1 ASL ATP6V1G1 BANF2 BCL2L2-PABPN1 BEND5 BIRC7 BLMH BLOC1S6 BLZF1 BOLA2 BOLA2B BORCS6 BPIFB3 BTBD2 BTBD6 C1orf50 CAMK2A CAPN3 CARD9 CASP6 CAVIN4 CBFA2T2 CBS CBY2 CCDC102B CCDC152 CCDC184 CCDC197 CCHCR1 CCNB1IP1 CD22 CDA CDCA8 CDK2AP1 CDKN2AIPNL CDR2 CENPP CEP170B CEP55 CEP70 CEP85 CGGBP1 CHCHD3 CHMP4A CMTM5 COG6 COIL CRYAA CSNK2B CT45A1 CTAG1A CTAG1B CTBP1 CTH CUEDC1 CUTC CYSRT1 DAB1 DCTPP1 DEUP1 DHPS DNAL4 DNM2 DYNLT1 EDARADD EGLN3 EIF2B1 EIF4G1 EMILIN3 ENOX2 EP400 EPN3 ETV6 EXOSC8 FAM136A FAM72A FAM72D FKBP6 FTH1 FTL GADD45GIP1 GAS7 GCSAML GFAP GMCL1 GMDS GNG3 GNMT GNPDA2 GOLGA2 GOLGA6L9 GPX7 GRAMD4 GSTA4 GSTO2 GTF2H2C H2AP HAUS8 HBQ1 HBZ HEATR5A HGD HIGD1C HMG20A HOMER3 HOXB6 HPRT1 HSD17B14 HSF2BP HSPE1 HUS1 IKZF3 IL16 IL31 INCA1 ISCA2 ITGB3BP JAKMIP2 JUP KASH5 KATNBL1 KCNH1 KCTD1 KCTD10 KCTD13 KCTD15 KCTD21 KCTD4 KCTD6 KCTD7 KCTD9 KEAP1 KIF21B KLHL12 KLHL2 KLHL20 KRT27 KRT31 KRTAP10-5 KRTAP10-7 KRTAP19-2 KRTAP19-6 KRTAP3-1 KRTAP3-3 KRTAP4-2 KRTAP5-9 KRTAP6-1 KRTAP9-2 KRTAP9-4 KRTAP9-8 L3MBTL3 LCE1C LCE1D LCE1E LCE1F LCE2C LCE5A LDB2 LENG1 LGALS2 LGALS9B LIN7B LMNA LMO1 LMO2 LMO3 LNX2 LONRF1 LRIF1 LRRC73 LSM12 LSM14B LZTFL1 LZTS1 LZTS2 MAB21L3 MAD1L1 MAGEA11 MAGEA12 MAGEA2 MAGEA2B MALSU1 MARCHF10 MATN4 MDFI MED22 MIF MIF4GD MIOS MIPOL1 MIS18A MITD1 MOB2 MORN3 MPLKIP MRFAP1L1 MRPL12 MTHFD2L MTUS2 MVP MXRA8 MYD88 N4BP3 NAB2 NADSYN1 NAGK NCOA5 NDUFAB1 NECAB2 NME1 NPL NR5A1 NT5C1A NTAN1 NUDT14 NUDT16L1 NUDT21 OOEP PAK5 PCBD1 PFDN5 PGPEP1 PIH1D2 PLA2G10 PLCD1 PLEKHB2 PLEKHJ1 PNMA1 PNMA2 PNMA5 POLR2J POMC PPCDC PPM1K PPP1R27 PRKAR1B PRMT1 PRMT5 PRPS2 PRR20A PRR20B PRR20C PRR20D PRR20E PRR23B PRTFDC1 PSMB5 PSME3 PTS PYCR3 PYGM RAB42 RABAC1 RASAL3 RBBP8 RBM20 RBM45 RBM48 RBPMS RD3 REEP6 RHOQ RILPL1 RNF138 RNF4 ROPN1 RPIA RUSC1 S100A11 SAP18 SARS2 SAT1 SCARA5 SELENOV SEPTIN14 SEPTIN3 SFN SH3GLB2 SIAH1 SIKE1 SIVA1 SLAIN1 SLC15A2 SLPI SMAP1 SMN1 SNAP29 SNRPD3 SPANXB1 SPATA32 SPDYE4 SPINDOC SPRYD7 SSNA1 SSX2IP STH STMN2 STN1 STX11 SYCE1L SYNGAP1 TAX1BP1 TBX15 TCL1A TCP10L TEKT1 TEPSIN THAP1 THAP6 THAP7 THG1L TICAM2 TIFA TLE5 TMEM239 TNFAIP1 TNIP3 TNR TOLLIP TRAF1 TRAF3 TRAF5 TRIM23 TRIM27 TRIM32 TRIM5 TRIM54 TRIM69 TRIM73 TRIM9 TRIP13 TSC22D1 TSN TSNAX UBR1 UBR2 UFC1 UNKL VAC14 VCP VDR VMA22 VPS37C VXN XIAP ZBED1 ZBTB8A ZBTB8B ZC2HC1C ZCCHC17 ZNF165 ZNF341 ZNF436 ZNF511 ZNF618 ZSCAN16 ZSCAN32	113 interacting genes: ABI2 ANKRD55 ATOSB BCAS2 BCL6 BHLHE40 BRMS1 C10orf55 C10orf62 C22orf39 CALCOCO2 CCDC198 CEBPA CIMIP1 CSPP1 DMRT3 DOK4 DOK5 EEIG1 ELK3 ESPNL FAAP20 FAM110A FAM221A FAM222B FAM90A1 GLRX3 GLYCTK GPANK1 GSTO2 GUCD1 HAPLN2 HHEX HOXB9 HOXC8 IKBKG IKZF3 IL16 INCA1 IRX2 IRX6 ITSN1 KCTD9 KDM1A KLHL38 KLHL42 LARP4 LNX1 MAP2K5 METTL21A MISP MRPL45 MYC MYOT MYOZ1 NEUROG2 NOXA1 NTAQ1 PATZ1 PAX9 PFDN6 PHF1 PHF24 PILRA PITX1 PITX2 POGZ PRKAB2 PRPF18 PRR35 PSMB4 PSMB8 PSME3 RIBC1 RIPPLY1 RSRC2 RUSC1 SAXO1 SAXO4 SCNM1 SDCBP SHISA6 SLAIN1 SMAP1 SMG9 SNAI1 SNRNP25 SNRPB SOHLH1 SPAG8 SPG21 SPMIP2 SPMIP4 SYCE1L SYT17 TAF6L TBX3 TCF19 TFG TLE5 TP73 TRAPPC6A TRIM28 TUBA1B TUBA3C VAX2 VEZF1 VGLL1 WDR25 WHR1 YPEL5 ZC2HC1C ZNF148
Entrez ID		55093	5204
HPRD ID		07653	05359
Ensembl ID		ENSG00000156795	ENSG00000123349
Uniprot IDs		E5RHC2 Q96HA8	Q99471
PDB IDs		3C9Q 4W79 6KGJ 8JJF 8JJG 8JJH 8JJI 8JJU 8JJW 8JJX 8JJY 8JJZ 8JK0 8JK1 8JK2	6NR8 6NR9 6NRB 6NRC 6NRD 7WU7
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Cytosol Protein Homooligomerization Protein Complex Oligomerization Cytoplasm Intermediate Filament Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Protein Sumoylation Keratin Filament Sulfur Amino Acid Metabolic Process Regulation Of Protein Sumoylation Protein-containing Complex Assembly Keratinization Ubiquitin-protein Transferase Activity N-acetylneuraminate Catabolic Process Protein Tetramerization Purine Nucleoside Metabolic Process Amino Acid Metabolic Process Cul3-RING Ubiquitin Ligase Complex	Protein Binding Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Chromatin Negative Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of RNA Metabolic Process Pattern Specification Process MRF Binding Regionalization Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process E-box Binding Axonemal A Tubule Inner Sheath
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